Monoclonal Antibody to Insulin (INS) Homo sapiens (Human) Monoclonal antibody

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Overview
Properties
  • SourceMonoclonal antibody preparation, Host Mouse
  • Ig Isotype IgG1 Kappa, Clone Number C1
  • PurificationProtein A + Protein G affinity chromatography
  • LabelNone
  • Immunogen RPA448Hu02-Recombinant Insulin (INS)
  • Buffer Formulation0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
  • TraitsLiquid, Concentration 1mg/ml
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  • Monoclonal Antibody to Insulin (INS) Packages (Simulation)
  • Monoclonal Antibody to Insulin (INS) Packages (Simulation)
  • Monoclonal Antibody to Insulin (INS) IHC Images
  • MAA448Hu22.jpg Western Blot; Sample: Mouse Pancreas lysate Primary Ab: 5μg/ml Mouse Anti-Human INS Antibody Second Ab: 0.2µg/mL HRP-Linked Caprine Anti-Mouse IgG Polyclonal Antibody (Catalog: SAA544Mu19)
  • Monoclonal Antibody to Insulin (INS) Western Blot; Sample: Porcine Pancreas lysate
    Primary Ab: 2µg/ml Mouse Anti-Human INS Antibody
    Second Ab: 0.2µg/mL HRP-Linked Caprine Anti-Mouse IgG Polyclonal Antibody
    (Catalog: SAA544Mu19)
  • Certificate ISO9001: 2008, ISO13485: 2003 Registered

Specifity

The antibody is a mouse monoclonal antibody raised against INS. It has been selected for its ability to recognize INS in immunohistochemical staining and western blotting.

Usage

Western blotting: 0.01-5µg/mL;
Immunohistochemistry: 5-20µg/mL;
Immunocytochemistry: 5-20µg/mL;
Optimal working dilutions must be determined by end user.

Storage

Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

Stability

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Organism Species More: Sus scrofa; Porcine (Pig)

Giveaways

Citations

  • Impaired neural stem/progenitor cell proliferation in Streptozotocin-induced and spontaneous diabetic micePubMed: 20832431
  • Nicotinamide-functionalized multiwalled carbon nanotubes increase insulin production in pancreatic beta cells via MIF pathwayPubMed: PMC3770514
  • Metformin Inhibits Expression and Secretion of PEDF in Adipocyte and Hepatocyte via Promoting AMPK PhosphorylationPubmed: 24288442
  • Polo Like Kinase 1 (Plk1) Expression in Visceral Adipose Tissue of Morbidly Obese Non Diabetic WomenUsa-journals: Source
  • Effect of the “protein diet” and bone tissue.Pubmed: 24483972
  • Rosiglitazone Inhibits Expression and Secretion of PEDF in Adipose Tissue and Liver of Male SD Rats Via a PPAR-γ Independent MechanismEndocrine: Source
  • CORRELA??ES ENTRE METABóLITOS E HORM?NIOS NO PERíODO DE TRANSI??O DE VACAS DE CORTE DE DIFERENTES GENóTIPOS CRIADAS NO SUL DO BRASIL Cnptia:Source
  • CONCENTRA??ES SéRICAS DE INSULINA NO PóS-PARTO RECENTE DE VACAS DE CORTE DE DIFERENTES GENóTIPOS CRIADAS NO SUL DO BRASILAlice:Source
  • Tinospora crispa Ameliorates Insulin Resistance Induced by High Fat Diet in Wistar RatsPubmed:Pmc4363645
  • Zataria multiflora increases insulin sensitivity and PPARγ gene expression in high fructose fed insulin resistant ratsPubmed:Pmc4046234
  • Perinatal low-dose iron treatment influences susceptibility to diet-induced adipogenesis in early-aged male Wistar ratsPubmed:24519243
  • Effect of NUCKS-1 Overexpression on cytokine profiling in obese women with breast cancerPubmed:24568505
  • Antioxidative effects of Korean red ginseng in postmenopausal women: A double-blind randomized controlled trialPubmed:24814037
  • Effect of Sleeve Gastrectomy Plus Side-to-Side Jejunoileal Anastomosis for Type 2 Diabetes Control in an Obese Rat ModelPubMed: 26202420
  • Tinospora crispaPubMed: 25821506
  • Taraxacum officinaleIndex.Php: Ijbcs
  • IDENTIFICATION OF MODULATORS OF BINDING PROPERTIES OF ANTIBODIES REACTIVE WITH A MEMBER OF THE INSULIN RECEPTOR FAMILYY2015: 0301040.Html
  • Structural and functional abnormalities of hepatic tissues in male Wistar rats fed hyperwhey and super amino anabolic proteinPubmed:27158055
  • Subcutaneous administration of liraglutide ameliorates learning and memory impairment by modulating tau hyperphosphorylation via the glycogen synthase kinase-3尾 pathway in an amyloid 尾 protein induced alzheimer disease mouse modelPubmed:27131827
  • Improvement of oral contraceptive-induced glucose dysreCavia (Guinea pig )lation and dyslipidemia by valproic acid is independent of circulating corticosteronePubmed:26855320
  • Activation of cardiac renin–angiotensin system and plasminogen activator inhibitor-1 gene expressions in oral contraceptive-induced cardiometabolic disorderPubmed:26934364
  • The dynamic three-dimensional culture of islet-like clusters in decellularized liver scaffoldsPubmed:26796204
  • Trigonella foenum-graecum water extract improves insulin sensitivity and stimulates PPAR and γ gene expression in high fructose-fed insulin-resistant ratspmc:PMC4817393
  • Central injection of GALR1 agonist M617 attenuates diabetic rat skeletal muscle insulin resistance through the Akt/AS160/GLUT4 pathwayPubmed:27041232
  • Fat and Sucrose Intake Induces Obesity‐Related Bone Metabolism Disturbances: Kinetic and Reversibility Studies in Growing and Adult RatsPubmed:26175082
  • Molecular characterization of insulin resistance and glycolytic metabolism in the rat uteruspubmed:27461373
  • Low Circulating Vaspin Level is not associated with Insulinemic Status in Impaired Glucose Tolerant Subjectsprofile:Muhammad_Saiedullah
  • Metformin Reduces Oxidative Stress Status and Improves Plasma Insulin Level in Streptozotocin-Induced Diabetic Ratspms:index.php
  • Metformin Ameliorates Uterine Defects in a Rat Model of Polycystic Ovary Syndrome.pubmed:28336389
  • Circulating Betatrophin and Hepatocyte Growth Factor in Type 2 Diabetic Patients: Their Relationship With Disease Prognosis405
  • Subcutaneous liraglutide ameliorates methylglyoxal-induced Alzheimer-like tau pathology and cognitive impairment by modulating tau hyperphosphorylation and glycogen synthase kinase-3β.pubmed:28337257
  • Irisin improves perivascular adipose tissue dysfunction via regulation of the heme oxygenase-1/adiponectin axis in diet-induced obese micepubmed:27638193
  • The anti-hyperglycemic efficacy of a lipid-lowering drug Daming capsule and the underlyingsignaling mechanisms in a rat model of diabetes mellitus.pubmed:27721485
  • Adiponectin protects the rats liver against chronic intermittent hypoxia induced injury throughAMP-activated protein kinase pathway.pubmed:27678302
  • Vitamin D3 intake as regulator of insulin degrading enzyme and insulin receptor phosphorylationin diabetic rats.pubmed:27930980
  • Regulation of insulin receptor phosphorylation in the brains of prenatally stressed rats: New insight into the benefits of antidepressant drug treatment.pubmed:28063625
  • Baicalin against obesity and insulin resistance through activation of AKT/AS160/GLUT4 pathwaypubmed:28359800
  • Ginsenoside Rg5 attenuates hepatic glucagon response via suppression of succinate-associated HIF-1α induction in HFD-fed micepubmed:28280902
  • Modulation of gut microbiota contributes to curcumin-mediated attenuation of hepatic steatosis in ratspubmed:28341485
  • High plasma glucagon levels correlate with waist-to-hip ratio, supra-iliac skinfold thickness, deep subcutaneous abdominal and intra-peritoneal adipose tissue …2376016.pdf
  • Berberis integerrima ameliorates insulin resistance in high-fructose-fed insulin-resistant ratspubmed:29147484
  • Red paprika (Capsicum annuum L.) and its main carotenoid capsanthin ameliorate impaired lipid metabolism in the liver and adipose tissue of high-fat diet-induced obese mice 10.1016:j.jff.2017.01.044
  • High circulating plasma dipeptidyl peptidase- 4 levels in non-obese Asian Indians with type 2 diabetes correlate with fasting insulin and LDL-C levels, triceps skinfolds, total intra-abdominal adipose tissue volume and presence of diabetes: a case–control study10.1136:bmjdrc-2017-000393
  • Chronic high-protein diet induces oxidative stress and alters the salivary gland function in ratspubmed:28926744
  • C1q/TNF‐related protein 9 improves the anti‐contractile effects of perivascular adipose tissue via the AMPK‐eNOS pathway in diet‐induced obese micepubmed:28902432
  • Irisin Regulates Heme Oxygenase-1/ Adiponectin Axis in Perivascular Adipose Tissue and Improves Endothelial Dysfunction in Diet-Induced Obese Micepubmed:28595178
  • Activiated Galanin receptor 2 attenuates insulin resistance in skeletal muscle of obese micepubmed:29183756
  • High Plasma Glucagon Levels Correlate with Waist-to-Hip Ratio, Suprailiac Skinfold Thickness, and Deep Subcutaneous Abdominal and Intraperitoneal Adipose Tissue Depots in Nonobese Asian Indian Males with Type 2 Diabetes in North India10.1155/2017/2376016
  • Central injection of GALR1 agonist M617 attenuates diabetic rat skeletal muscle insulin resistance through the Akt/AS160/GLUT4 pathwaypubmed:27041232
  • Antihyperglycemic Effect of Rosa Damascena is Mediated by PPAR.γ Gene Expression in Animal Model of Insulin Resistancepubmed:29201096
  • Effects of Bariatric Surgery on Change of Brown Adipocyte Tissue and Energy Metabolism in Obese Micepubmed:28853013
  • Relationship between serum leptin concentration and insulin resistance syndrome in patients with type 2 diabetes mellitusissn/2357-0121
  • Nanoformulated natural therapeutics for management of streptozotocin-induced diabetes: potential use of curcumin nanoformulationpubmed:28635562
  • Synthesis and anti-diabetic activity of new N,N-dimethylphenylenediamine-derivatized nitrilotriacetic acid vanadyl complexes.pubmed:28709620
  • The Effects of Duodenojejunal Omega Switch in Combination with High-Fat Diet and Control Diet on Incretins, Body Weight, and Glucose Tolerance in Sprague-Dawley Rats.pubmed:28840471
  • Adipose tissue complement factor B promotes adipocyte maturation.pubmed:29137982
  • The Role of Insulin Therapy in Correcting Hepcidin Levels in Patients with Type 2 Diabetes Mellitus.pubmed:28584599
  • Insulin restores UCP3 activity and decreases energy surfeit to alleviate lipotoxicity in skeletal musclepubmed:29039450
  • Changes in pancreatic histology, insulin secretion and oxidative status in diabetic rats following treatment with Ficus deltoidea and vitexinpubmed:28576138
  • Nypa fruticans Wurmb. Vinegar's Aqueous Extract Stimulates Insulin Secretion and Exerts Hepatoprotective Effect on STZ-Induced Diabetic Ratspubmed:28832548
  • Beneficial effects of Heqi san on rat model of polycystic ovary syndrome through the PI3K/AKT pathwaypubmed:29020999
  • Improvement of spatial learning and memory, cortical gyrification patterns and brain oxidative stress markers in diabetic rats treated with Ficus deltoidea leaf extract and vitexin.pubmed:29322009
  • The potential role of sitagliptin as an oral treatment regimen for type I diabetes mellitus ISSN: 2321-3086
  • Peripheral insulin resistance in ILK-depleted mice by reduction of GLUT4 expression.pubmed:28490443
  • The deubiquitinating enzyme cylindromatosis mitigates nonalcoholic steatohepatitisPubmed:29291351
  • The Effect of Distal-ileal Exclusion After Roux-en-Y Gastric Bypass on Glucose Tolerance and GLP-1 Response in Type-2 Diabetes Sprague-Dawley Rat Model10.1016:j.soard.2018.07.009
  • Preserving Duodenal-Jejunal (Foregut) Transit Does Not Impair Glucose Tolerance and Diabetes Remission Following Gastric Bypass in Type 2 Diabetes Sprague …Pubmed:29098544
  • Ileal Transposition Surgery Decreases Fat Mass and Improves Glucose Metabolism in Diabetic GK Rats: Possible Involvement of FGF21Pubmed:29593555
  • Crocin mediated amelioration of oxidative burden and inflammatory cascade suppresses diabetic nephropathy progression in diabetic ratsPubmed:29409856
  • Effects of dietary leucine and phenylalanine on pancreas development, enzyme activity, and relative gene expression in milk-fed Holstein dairy calvesPubmed:29477524
  • Beneficial effect of baicalin on insulin sensitivity in adipocytes of diet-induced obese micePubmed:29526684
  • Anti-obesity properties of the strain subsp. CECT 8145 in Zücker fatty ratsPubmed:29695181
  • Vildagliptin/pioglitazone combination improved the overall glycemic control in type I diabetic ratsPubmed:29510081
  • Effects of biotin and nicotinamide supplementation on glucose and lipid metabolism and milk production of transition dairy cows10.1016:j.anifeedsci.2018.01.012
  • Diet enriched with fresh coconut decreases blood glucose levels and body weight in normal adultsPubmed:29461972
  • Liraglutide exerts a bone‑protective effect in ovariectomized rats with streptozotocin‑induced diabetes by inhibiting osteoclastogenesisPubmed:29805533
  • Effects of Intrauterine Growth Retardation on Growth, Meat Quality and Muscle Fiber Composition of Pigs.:
  • Hyperandrogenism and insulin resistance contribute to hepatic steatosis and inflammation in female rat liverPubmed:29719598
  • The protective effect of Azadirachta excelsa leaves extract and quercetin treatment on the learning and memory impairments in relation with insulin and amylin …10.1016:j.jksus.2018.05.017
  • 组织蛋白酶G 在1 型糖尿病小鼠CD+ 4T 淋巴细胞活化过程中的作用.Ebscohost:Source
  • Effects of Acute Cold Stress on Liver O-GlcNAcylation and Glycometabolism in MicePubmed: 30231545
  • Transcriptomic analysis reveals effects of fucoxanthin on intestinal glucose transportDoi: 10.1016/j.jff.2018.08.018
  • Targeted folate-conjugated pluronic P85/poly(lactide--glycolide) polymersome for the oral delivery of insulinDoi: 10.2217/nnm-2017-0372
  • Effect of Baicalein on GLUT4 Translocation in Adipocytes of Diet-Induced Obese MicePubmed: 30308480
  • The decline of whole-body glucose metabolism in ovariectomized ratsPubmed: 30292771
  • Intermedin in Paraventricular Nucleus Attenuates Sympathoexcitation and Decreases TLR4-Mediated Sympathetic Activation Adrenomedullin Receptors in Rats …Pubmed: 30276527
  • Alterations in lipid peroxidation, lipid profile, insulin sensitivity, and hepatic histopathological changes in diabetic rats following the treatment withPubmed: 30270568
  • Effects of feeding frequency during lactation in primiparous sows on reproduction performance and diurnal rhythm of endocrine profiles at the weaning-to-ovulation …
  • The Changes of Serum Metabolites in Diabetic GK Rats after Ileal Transposition SurgeryPubmed: 30397878
  • Silencing of LncRNA Steroid Receptor RNA Activator attenuates polycystic ovary syndrome in MicePubmed: 30391287
  • Geniposide and Gentiopicroside Suppress Hepatic Gluconeogenesis via Regulation of AKT-FOXO1 PathwayPubmed: 30409503
  • Effects of lycopene on metabolism of glycolipid in type 2 diabetic ratsPubmed: 30551463
  • Uterine progesterone signaling is a target for metformin therapy in polycystic ovary syndromePubmed: 29535146
  • Plasma Cellular Hypoxia, Mitochondrial Dysfunction, Disease Risk and Prognostic Factors in Type 2 Diabetic Patients in Saudi Arabia.
  • Enhanced oral absorption of insulin using colon-specific nanoparticles co-modified with amphiphilic chitosan derivatives and cell-penetrating peptidesPubmed: 30672923
  • Treatment with celastrol protects against obesity through suppression of galanin-induced fat intake and activation of PGC-1α/GLUT4 axis-mediated glucose …Pubmed: 30742994
  • The Effect of Gastric Bypass with a Distal Gastric Pouch on Glucose Tolerance and Diabetes Remission in Type 2 Diabetes Sprague-Dawley Rat ModelPubmed: 30778846
  • Curcumin Ameliorates the Impaired Insulin Signaling Involved in the Pathogenesis of Alzheimer's Disease in Rats
  • Regulating glycolysis, the TLR4 signal pathway and expression of RBM3 in mouse liver in response to acute cold exposurePubmed: 30821572
  • Interrelation of liver vascularity to non-alcoholic fatty liver through a comparative study of the vasodilator effect of carvedilol or nicorandil in ratsPubmed: 30826497
  • Regulation of insulin resistance by targeting insulin‐like growth factor 1 receptor (IGF‐1R) with microRNA‐122‐5p in hepatic cellsPubmed: 30958584
  • Effects of Cold-inducible RNA-binding Protein (CIRP) on Liver Glycolysis during Acute Cold Exposure in C57BL/6 MicePubmed: 30909542
  • Dobesity: relationship between vitamin d deficiency, obesity and sclerostin as a novel biomarker of bone metabolism
  • Huperzine A ameliorates obesity-related cognitive performance impairments involving neuronal insulin signaling pathway in micePubmed: 31213670
  • Protective Effect of Peroxiredoxin 6 Against Toxic Effects of Glucose and Cytokines in Pancreatic RIN-m5F β-Cells
  • Tempol alleviates chronic intermittent hypoxia-induced pancreatic injury through repressing inflammation and apoptosis.Pubmed: 31301730
  • Glycerol Monolaurate‐Mediated Attenuation of Metabolic Syndrome is Associated with the Modulation of Gut Microbiota in High Fat diet‐fed MicePubmed: 31318165
  • Associations of apelin, leptin, irisin, ghrelin, insulin, glucose levels, and lipid parameters with physical activity during eight weeks of regular exercise trainingPubmed: 31290696
  • Efeito do consumo crônico de óleo de coco sobre parâmetros bioquímicos e do status redox em ratas saudáveis.
  • Liraglutide Combined with Human Umbilical Cord Mesenchymal Stem Cell Transplantation inhibits beta‐cells apoptosis via mediating the ASK1/JNK/BAX pathway in Pubmed: 31411368
  • Baicalin ameliorates hepatic insulin resistance and gluconeogenic activity through inhibition of p38 MAPK/PGC-1α pathway
  • Coptisine ameliorates renal injury in diabetic rats through the activation of Nrf2 signaling pathwayPubmed: 31420722
  • High-dose Glycerol Monolaurate Up-Regulated Beneficial Indigenous Microbiota without Inducing Metabolic Dysfunction and Systemic Inflammation: New Insights …
  • MicroRNA-99a is a Potential Target for Regulating Hypothalamic Synaptic Plasticity in the Peri/Postmenopausal Depression ModelPubmed: 31540304
  • Metformin alleviates oxidative stress and enhances autophagy in diabetic kidney disease via AMPK/SIRT1-FoxO1 pathwayPubmed: 31647955
  • Duodenal-Jejunal Bypass Ameliorates Type 2 Diabetes Mellitus by Activating Insulin Signaling and Improving Glucose Utilization in the BrainPubmed: 31605365
  • Distal gastric mucosa ablation induces significant weight loss and improved glycemic control in type 2 diabetes Sprague–Dawley rat modelPubmed: 31630290
  • Propolis modulates the gut microbiota and improves the intestinal mucosal barrier function in diabetic ratsPubmed: 31545258
  • miR-29a Negatively Affects Glucose-Stimulated Insulin Secretion and MIN6 Cell Proliferation via Cdc42/β-Catenin SignalingPubmed: 31662747
  • Depolymerized RG-I enriched pectin from citrus segment membrane modulates gut microbiota, increases SCFAs production, promotes the growth of Bifidobacterium …Pubmed: 31778135
  • P-Coumaric acid alleviates experimental diabetic nephropathy through modulation of toll like receptor-4 in ratsPubmed: 31629762
  • Baicalin ameliorates polycystic ovary syndrome through AMP-activated protein kinasePubmed: 31722718
  • Dietary supplementation of Morus nigra L. leaves decrease fat mass partially through elevating leptin-stimulated lipolysis in pig modelPubmed: 31756448
  • Isoflurane aggravates peripheral and central insulin resistance in high-fat diet/streptozocin-induced type 2 diabetic micePubmed: 31672472
  • San-Huang-Tang protects obesity/diabetes induced NAFLD by upregulating PGC-1α/PEPCK signaling in obese and galr1 knockout mice modelsPubmed: 31843573
  • Triphenyl phosphate causes a sexually dimorphic metabolism dysfunction associated with disordered adiponectin receptors in pubertal micePubmed: 31796355
  • SerpinB1 promotes the proliferation of porcine pancreatic stem cells through the STAT3 signaling pathwayPubmed: 31785377
  • Liraglutide improved inflammation via mediating IL-23/Th-17 pathway in obese diabetic mice with psoriasiform skinPubmed: 31868553
  • Rotundic Acid Protects against Metabolic Disturbance and Improves Gut Microbiota in Type 2 Diabetes RatsPubmed: 31887996
  • Decreased amylolytic microbes of the hindgut and increased blood glucose implied improved starch utilization in the small intestine by using rumen-protected leucine …Pubmed: 32113753
  • Composite probiotics alleviate type 2 diabetes by regulating intestinal microbiota and inducing GLP-1 secretion in db/db micePubmed: 32035395
  • Hyperbaric oxygen ameliorates insulin sensitivity by increasing GLUT4 expression in skeletal muscle and stimulating UCP1 in brown adipose tissue in T2DM …Pubmed: 32082261
  • Integrin Linked Kinase (ILK) Downregulation as an Early Event During the Development of Metabolic Alterations in a Short-Term High Fat Diet Mice Model.Pubmed: 31972071
  • Beneficial effects of Aronia melanocarpa berry extract on hepatic insulin resistance in type 2 diabetes mellitus ratsPubmed: 32249934
  • Roux-en-Y Gastric Bypass in Obese Diabetic Rats Promotes Autophagy to Improve Lipid Metabolism through mTOR/p70S6K Signaling PathwayPubmed: 32309446
  • Electroacupuncture improves cognitive deficits and insulin resistance in an OLETF rat model of Al/D-gal induced aging model via the PI3K/Akt signaling pathwayPubmed: 32304687
  • Mice with nucleus tractus solitarius injury induced by chronic restraint stress present impaired ability to raise blood glucose and glucagon levels when blood glucose …Pubmed: 32249244
  • RFRP-3, the Mammalian Ortholog of GnIH, Is a Novel Modulator Involved in Food Intake and Glucose HomeostasisPubmed: 32328034
  • Effects of Allicin on Pathophysiological Mechanisms during the Progression of Nephropathy Associated to DiabetesPubmed: 33203103
  • AdipoR1/AdipoR2 dual agonist recovers nonalcoholic steatohepatitis and related fibrosis via endoplasmic reticulum-mitochondria axisPubmed: 33199780
  • Evaluation of the hypoglycemic effect of exendin-4's new oral self-nanoemulsifying system in ratsPubmed: 33197556
  • Novel mechanisms underlying anti-polycystic ovary like syndrome effects of electroacupuncture in rats: suppressing SREBP1 to mitigate insulin resistance …Pubmed: 33109277
  • Irradiation of carotid baroreceptor with low‐intensity pulsed ultrasound exerts different metabolic protection in perirenal, epididymal white adipose tissue and …Pubmed: 32954574
  • Palmatine ameliorates high fat diet induced impaired glucose tolerancePubmed: 32928312
  • Thioredoxin-interacting protein: a critical link between autophagy disorders and pancreatic β-cell dysfunctionPubmed: 32892310
  • Adiponectin treatment improves insulin resistance in mice by regulating the expression of the mitochondrial-derived peptide MOTS-c and its response to exercise via …Pubmed: 32880686
  • Insulin promotes corneal nerve repair and wound healing in type 1 diabetic mice by enhancing Wnt/β-catenin signalingPubmed: 32858016
  • Aplysin Retards Pancreatic Necrosis and Inflammatory Responses in NOD Mice by Stabilizing Intestinal Barriers and Regulating Gut Microbial CompositionPubmed: 32801992
  • Gut microbiota modulation as a promising therapy with metformin in rats with non-alcoholic steatohepatitis: Role of LPS/TLR4 and autophagy pathwaysPubmed: 32758573
  • MiRNAs expression profiling of rat ovaries displaying PCOS with insulin resistancePubmed: 32757043
  • Modulatory role of imatinib mesylate on pancreatic β-cells' secretory functions in an STZ rat model of diabetes mellitusPubmed: 32710900
  • Electroacupuncture alleviates polycystic ovary syndrome-like symptoms through improving insulin resistance, mitochondrial dysfunction, and endoplasmic …Pubmed: 32698821
  • Highly Branched RG-I Domain Enrichment are Indispensable for Pectin Mitigating Against High-Fat Diet-Induced ObesityPubmed: 32633953
  • Integrated metabolomics and gut microbiome to the effects and mechanisms of naoxintong capsule on type 2 diabetes in ratsPubmed: 32616735
  • Activation of central galanin receptor 2 mitigated insulin resistance in adipocytes of diabetic ratsPubmed: 32588381
  • The neuroprotective effect of simvastatin on the cerebellum of experimentally-induced diabetic rats through klotho upregulation: An immunohistochemical studyPubmed: 32479899
  • Regulation and Mechanism of miR-518d through the PPARα-Mediated NF-κB Pathway in the Development of Gestational Diabetes MellitusPubmed: 33123597
  • Cooperative effects of galanin and leptin on alleviation of insulin resistance in adipose tissue of diabetic ratsPubmed: 32395890
  • Pathophysiological Changes in Female Rats with Estrous Cycle Disorder Induced by Long-Term Heat StressPubmed: 32685488
  • MiR-185-5p Protects Against Angiogenesis in Polycystic Ovary Syndrome by Targeting VEGFAPubmed: 32760272
  • Therapeutic effects of organic zinc on reproductive hormones, insulin resistance and mTOR expression as a novel component in a rat model of PCOS
  • Fucoidan prevent murine autoimmune diabetes via suppression TLR4-signaling pathways, regulation DC/Treg induced immune tolerance and improving gut …
  • Different source of commercial vegetable oils may regulate metabolic, inflammatory and redox status in healthy rats
  • Comparative transcriptomic and metabolomic analysis reveals pectoralis highland adaptation across altitudinal songbirds
  • The effects of different intensity endurance and resistance exercise on diabetic-related blood profiles in impaired glucose tolerance mice
  • Phosphorylation of eIF2¦Á signaling pathway attenuates obesity-induced non-alcoholic fatty liver disease in an ER stress and autophagy-dependent manner33318479
  • Empagliflozin improves chronic hypercortisolism-induced abnormal myocardial structure and cardiac function in mice33294147
  • Time-restricted feeding attenuates gluconeogenic activity through inhibition of PGC-1¦Á expression and activity33412190
  • Physiological and genetic convergence supports hypoxia resistance in high-altitude songbirds33370292
  • N1?methylnicotinamide ameliorates insulin resistance in skeletal muscle of type 2 diabetic mice by activating the SIRT1/PGC?1¦Á signaling pathway33576435
  • Inverse association of plasma hydrogen sulfide levels with visceral fat area among Chinese young men: a cross-sectional study33740335
  • Ileal transposition helps to regulate plasma hepatokine levels in obese Zucker (Crl: ZUC (ORL)-Lepr fa) rats33833309
  • miR-155-5p upregulation ameliorates myocardial insulin resistance via mTOR signaling in chronic alcohol drinking rats33868799
  • Identification of curcumin as a potential ¦Á©\glucosidase and dipeptidyl©\peptidase 4 inhibitor: Molecular docking study, in vitro and in vivo biological evaluation33817806
  • Consumption of soybean or olive oil at recommended concentrations increased the intestinal microbiota diversity and insulin sensitivity and prevented fatty liver?¡­33915261
  • TMBIM1 is an inhibitor of adipogenesis and its depletion promotes adipocyte hyperplasia and improves obesity-related metabolic disease34107313
  • Dapagliflozin: a Sodium-glucose Cotransporter 2 Inhibitor, Attenuates Angiotensin II-induced Cardiac Fibrotic Remodeling by Regulating TGF¦Â1/Smad ¡­34116674
  • Different Ratios of Corn and Coconut Oil Blends in High©\Fat Diets Influence Fat Deposition without Altering Metabolic Biomarkers in Male Rats
  • DAla2-GIP-GLU-PAL Protects Against Cognitive Deficits and Pathology in APP/PS1 Mice by Inhibiting Neuroinflammation and Up-regulating cAMP/PKA/CREB?¡­
  • Investigation of extracellular matrix genes associated with Alzheimer's disease in the hippocampus of experimental diabetic model rats
  • Ficus deltoidea ameliorates biochemical, hormonal, and histomorphometric changes in letrozole-induced polycystic ovarian syndrome rats
  • Intermittent Fasting Attenuates High Fat Diet-Induced Cerebellar Changes in Rats: Involvement of TNFα, autophagy and oxidative stress34551416
  • Bee venom ameliorates cardiac dysfunction in diabetic hyperlipidemic rats34550826
  • Baicalin protects against insulin resistance and metabolic dysfunction through activation of GALR2/GLUT4 signaling34923235
  • Lactobacillus acidophilus ameliorates obesity in mice through modulation of gut microbiota dysbiosis and intestinal permeability34896249
  • Time-restricted feeding prevents metabolic diseases through the regulation of galanin/GALR1 expression in the hypothalamus of mice34370270
  • Combined treatment of sinapic acid and ellagic acid attenuates hyperglycemia in streptozotocin-induced diabetic rats34329744
  • Spexin ameliorates skeletal muscle insulin resistance through activation of GAL2 receptorPubmed:34973950
  • The effect of bariatric surgery on the expression of Growth Differentiation Factor-15/Macrophage-Inhibitory Cytokine-1 (GDF-15/MIC-1) in ratPubmed:35029766
  • ATP6V1H deficiency impairs glucose tolerance by augmenting endoplasmic reticulum stress in high fat diet fed micePubmed:34990584
  • Environmental exposure to low-dose perfluorohexanesulfonate promotes obesity and non-alcoholic fatty liver disease in mice fed a high-fat dietPubmed:35217953
  • Intragastric safflower yellow and its main component HSYA improve leptin sensitivity before body weight change in diet-induced obese micePubmed:35201390
  • A cross-sectional comparative study on the effects of body mass index and exercise/sedentary on serum asprosin in male college studentsPubmed:35381008
  • Hepatic deficiency of selenoprotein S exacerbates hepatic steatosis and insulin resistancePubmed:35347118
  • A novel anti-obesity mechanism for liraglutide by improving adipose tissue leptin resistance in high-fat diet-fed obese micePubmed:35705299
  • Antioxidant Effect of Tyr-Ala Extracted from Zein on INS-1 Cells and Type 2 Diabetes High-Fat-Diet-Induced MicePubmed:35740008
  • Treatment with spexin mitigates diet-induced hepatic steatosis in vivo and in vitro through activation of galanin receptor 2Pubmed:35654225
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