CLIA Kit for Interleukin 6 (IL6) Homo sapiens (Human) Sandwich CLIA

MGI2-A; MGI2A; HGF; BSF2; HSF; IFNB2; B-Cell Stimulatory Factor-2; Hybridoma/Plasmacytoma Growth Factor; Hepatocyte Stimulating Factor; Cytotoxic T-Cell Differentiation Factor

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  • CLIA Kit for Interleukin 6 (IL6) Packages (Simulation)
  • CLIA Kit for Interleukin 6 (IL6) Packages (Simulation)
  • CLIA Kit for Interleukin 6 (IL6) Results demonstration
  • SCA079Hu.jpg Typical Standard Curve
  • Certificate ISO9001: 2008, ISO13485: 2003 Registered

Recovery

Matrices listed below were spiked with certain level of recombinant Interleukin 6 (IL6) and the recovery rates were calculated by comparing the measured value to the expected amount of Interleukin 6 (IL6) in samples.

Matrix Recovery range (%) Average(%)
serum(n=5) 97-105 101
EDTA plasma(n=5) 79-88 79
heparin plasma(n=5) 96-104 101

Precision

Intra-assay Precision (Precision within an assay): 3 samples with low, middle and high level Interleukin 6 (IL6) were tested 20 times on one plate, respectively.
Inter-assay Precision (Precision between assays): 3 samples with low, middle and high level Interleukin 6 (IL6) were tested on 3 different plates, 8 replicates in each plate.
CV(%) = SD/meanX100
Intra-Assay: CV<10%
Inter-Assay: CV<12%

Linearity

The linearity of the kit was assayed by testing samples spiked with appropriate concentration of Interleukin 6 (IL6) and their serial dilutions. The results were demonstrated by the percentage of calculated concentration to the expected.

Sample 1:2 1:4 1:8 1:16
serum(n=5) 98-105% 96-104% 89-104% 99-105%
EDTA plasma(n=5) 94-101% 79-103% 98-105% 95-104%
heparin plasma(n=5) 79-95% 85-99% 78-95% 92-99%

Stability

The stability of kit is determined by the loss rate of activity. The loss rate of this kit is less than 5% within the expiration date under appropriate storage condition.
To minimize extra influence on the performance, operation procedures and lab conditions, especially room temperature, air humidity, incubator temperature should be strictly controlled. It is also strongly suggested that the whole assay is performed by the same operator from the beginning to the end.

Reagents and materials provided

Reagents Quantity Reagents Quantity
Pre-coated, ready to use 96-well strip plate 1 Plate sealer for 96 wells 4
Standard 2 Standard Diluent 1×20mL
Detection Reagent A 1×120µL Assay Diluent A 1×12mL
Detection Reagent B 1×120µL Assay Diluent B 1×12mL
Substrate A 1×10mL Substrate B 1×2mL
Wash Buffer (30 × concentrate) 1×20mL Instruction manual 1

Assay procedure summary

1. Prepare all reagents, samples and standards;
2. Add 100µL standard or sample to each well. Incubate 1 hours at 37°C;
3. Aspirate and add 100µL prepared Detection Reagent A. Incubate 1 hour at 37°C;
4. Aspirate and wash 3 times;
5. Add 100µL prepared Detection Reagent B. Incubate 30 minutes at 37°C;
6. Aspirate and wash 5 times;
7. Add 100µL Substrate Solution. Incubate 10 minutes at 37°C;
8. Read RLU value immediately.

CLIA Kit for Interleukin 6 (IL6)

Test principle

The microplate provided in this kit has been pre-coated with an antibody specific to Interleukin 6 (IL6). Standards or samples are then added to the appropriate microplate wells with a biotin-conjugated antibody specific to Interleukin 6 (IL6). Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. Then the mixture of substrate A and B is added to generate glow light emission kinetics. Upon plate development, the intensity of the emitted light is proportional to the Interleukin 6 (IL6) level in the sample or standard.;

Citations

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  • Panax notoginseng saponins promote wound repair of anterior cruciate ligament through phosphorylation of PI3K, AKT and ERKPubmed:25755732
  • Inflammatory cytokines and acute-phase proteins concentrations in the peripheral blood and uterus of cows that developed endometritis during early postpartum.Pubmed:25765299
  • Pivotal role of mast cell carboxypeptidase A in mediating protection against small intestinal ischemia–reperfusion injury in rats after ischemic preconditioningSciencedirect:S0022480414004909
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  • Neuroprotective effect of allicin in a rat model of acute spinal cord injuryPubMed: 26546416
  • Hypoxia-induced secretion of IL-18 from adipose-derived mesenchymal stem cell promotes growth and cancer stem cell properties of Burkitt lymphomaPubMed: 26695151
  • Ultrasensitive photoelectrochemical immunoassay for CA19-9 detection based on CdSe@ZnS quantum dots sensitized TiO2NWs/Au hybrid structure amplified by quenching effect of Ab2@V2+PubMed: 26433066
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  • The immunomodulating effect of seminal plasma on T cellsPubMed: 25799173
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  • Inflammatory cytokines and acute-phase proteins concentrations in the peripheral blood and uterus of cows that developed endometritis during early postpartumPubMed: 25765299
  • Inflammatory cytokine and acute phase protein concentrations in the peripheral blood and uterine washings of cows with subclinical endometritis in the late postpartum periodPubMed: 25846950
  • Effects of prebiotic supplementation on the expression of proteins regulating iron absorption in anaemic growing ratsPubMed: 25745840
  • ЦитокCgi-Bin: Irbis_Nbuv
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  • Oxymatrine attenuates CCl 4-induced hepatic fibrosis via modulation of TLR4-dependent inflammatory and TGF-β1 signaling pathwaysPubmed:27179304
  • Hyperoxia disrupts the intestinal barrier in newborn ratsPubmed:27266842
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  • S-Propargyl-Cysteine, a Novel Hydrogen Sulfide Donor, Inhibits Inflammatory Hepcidin and Relieves Anemia of Inflammation by Inhibiting IL-6/STAT3 Pathway.pubmed:27649298
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  • Effects of budesonide on the lung functions, inflammation and apoptosis in a saline-lavagemodel of acute lung injury.pubmed:28195073
  • Dihydromyricetin Protects against Diabetic Cardiomyopathy in Streptozotocin-Induced DiabeticMice.pubmed:28421194
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  • Salusin-β contributes to oxidative stress and inflammation in diabetic cardiomyopathypubmed:28333148
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  • Transplantation of Autologous Bone Marrow Mononuclear Cells Regulates Inflammation in aRabbit Model of Carotid Artery Atherosclerosis.pubmed:27788500
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  • The long non-coding RNA Neat1 is an important mediator of the therapeutic effect of bexarotene on traumatic brain injury in micepubmed:28483659
  • Hydrogen-Rich Saline Attenuates Brain Injury Induced by Cardiopulmonary Bypass and Inhibits Microvascular Endothelial Cell Apoptosis Via the PI3K/Akt/GSK3β …pubmed:29040978
  • Sea cucumber saponins liposomes ameliorate obesity-induced inflammation and insulin resistance in high-fat diet-fed micepubmed:29292463
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  • Identification of a panel of serum protein markers in early stage of sepsis and its validation in a cohort of patientspubmed:28655573
  • A Systems Pharmacology Approach to Determine Active Compounds and Action Mechanisms of Xipayi KuiJie’an enema for Treatment of Ulcerative colitisdoi:10.1038/s41598-017-01335-w
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  • Expression and Role of the Calcium-Sensing Receptor in Rat Peripheral Blood Polymorphonuclear Neutrophilspubmed:29081886
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  • Tanshinone II is a potent candidate for treatment of lipopolysaccharide-induced acute lung injury in rat model10.3892/ol.2017.7581
  • Ginsenoside Rg1 inhibits inflammatory responses via modulation of the nuclear factor‑κB pathway and inhibition of inflammasome activation in alcoholic hepatitispubmed:29207044
  • Dexmedetomidine Alleviates HyperoxiaInduced Acute Lung Injury via Inhibiting NLRP3 Inflammasome Activationpubmed:28873369
  • Serum complement factor 5a levels are associated with nonalcoholic fatty liver disease in obese childrenDOI: 10.1111/apa.14106
  • Interleukin-17 antagonist attenuates lung inflammation through inhibition of the ERK1/2 and NF-κB pathway in LPS-induced acute lung injury10.3892/mmr.2017.6837
  • Bone marrow-derived mesenchymal stem cells alleviates renal injury in severe acute pancreatitis via RhoA/Rho kinaseISSN:1936-2625
  • Protective effect of salvianolic acid B against intestinal ischemia reperfusion-induced injury in a rat model10.4314/tjpr.v16i10.17
  • Esculentoside A ameliorates cecal ligation and puncture-induced acute kidney injury in rats pubmed:28637971
  • Coenzyme Q10 and niacin mitigate streptozotocin-induced diabetic encephalopathy in a rat modelpubmed:28560538
  • Alteration in some pro and anti-inflammatory cytokines associated with complete and incomplete gestation cycle of cows10.1080/09291016.2017.1319636
  • The effect of DL-, L-isomers and DL-hydroxy analog administered at 2 levels as dietary sources of methionine on the metabolic and antioxidant parameters and growth performance of turkeys10.3382/ps/pex099
  • The immune impact of mimic endoscopic retrograde appendicitis therapy and appendectomy on rabbits of acute appendicitis.pubmed:29029533
  • Pantoprazole blocks the JAK2/STAT3 pathway to alleviate skeletal muscle wasting in cancer cachexia by inhibiting inflammatory response.pubmed:28489606
  • Anemia and Iron Deficiency Related to Inflammation, Helicobacter pylori Infection and Adiposity in Reproductive-age Cuban Women10.1590/MEDICC.2017.1902030004 
  • Global gene expression profile of cerebral ischemia-reperfusion injury in rat MCAO modelpubmed:29088811
  • Neuroprotection of Botch in experimental intracerebral hemorrhage in rats.pubmed:29221132
  • Wpływ pola magnetycznego niskiej częstotliwości stosowanego w magnetoterapii na zawartość interleukiny 6 (il-6) w sercu i mózgu szczura 10.13075/mp.5893.00354
  • An ALOX12-12-HETE-GPR31 signaling axis is a key mediator of hepatic ischemia-reperfusion injury.pubmed:29227475
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  • Blocking the Feedback Loop between Neuroendocrine Differentiation and Macrophages Improves the Therapeutic Effects of Enzalutamide (MDV3100) on Prostate Cancer.pubmed:29191973
  • Altered gastrointestinal motility in an animal model of Lesch-Nyhan disease.pubmed:29305058
  • A study of altered cytokine rhythms associated with successful implantation in cows10.1080/09291016.2017.1361159
  • Calcitriol Ameliorates AngiotensinII-Induced Renal Injury Partly via Upregulating A20.pubmed:28744711
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  • Increased synovial lipodystrophy induced by high fat diet aggravates synovitis in experimental osteoarthritis.pubmed:29191221
  • Attenuation of acute systemic inflammatory response after valve surgeryISSN: 1556-4002
  • Cis-stilbene glucoside in Polygonum multiflorum induces immunological idiosyncratic hepatotoxicity in LPS-treated rats by suppressing PPAR-γ.pubmed:28649126
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  • Mild hypothermia pretreatment protects against liver ischemia reperfusion injury via the PI3K/AKT/FOXO3a pathwaypubmed:28944825
  • Secondary Haemophilus parasuis infection enhances highly pathogenic porcine reproductive and respiratory syndrome virus (HP-PRRSV) infection-mediated inflammatory responses.pubmed:28532803
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  • Inflammatory biomarkers and radiologic measurements in never-smokers with COPD: A cross-sectional study from the CODA cohort.pubmed:29117798
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  • Reciprocal network between cancer stem-like cells and macrophages facilitates the progression and androgen deprivation therapy resistance of prostate cancerPubmed:29691294
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  • Vasculotide, an angiopoietin-1 mimetic, restores microcirculatory perfusion and microvascular leakage and decreases fluid resuscitation requirements in …Pubmed:28968277
  • Activated Α7nachr Improves Postoperative Cognitive Dysfunction and Intestinal Injury Induced by Cardiopulmonary Bypass in Rats: Inhibition of the Proinflammatory …Pubmed:29672286
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  • Phytic acid improves intestinal mucosal barrier damage and reduces serum levels of proinflammatory cytokines in a 1, 2-dimethylhydrazine-induced rat colorectal …Pubmed:29947321
  • Ursolic Acid Ameliorates Inflammation in Cerebral Ischemia and Reperfusion Injury Possibly via High Mobility Group Box 1/Toll-Like Receptor 4/NFκB …Pubmed:29867706
  • Hepatoprotective effect of flavonoid-enriched fraction from Cyclocarya paliurus leaves on LPS/D-GalN-induced acute liver failure10.1016:j.jff.2018.07.031
  • Resolvin D2 protects against cerebral ischemia/reperfusion injury in ratsPubmed:29439730
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  • Lipoxin A4 may attenuate the progression of obesity-related glomerulopathy by inhibiting NF-κB and ERK/p38 MAPK-dependent inflammationPubmed:29499280
  • Dexmedetomidine attenuates renal fibrosis via α2-adrenergic receptor-dependent inhibition of cellular senescence after renal ischemia/reperfusionPubmed:29729264
  • Modified porcine surfactant enriched by recombinant human superoxide dismutase for experimental meconium aspiration syndromePubmed:29684443
  • Intra-arterial human urinary kallidinogenase alleviates brain injury in rats with permanent middle cerebral artery occlusion through PI3K/AKT/FoxO1 signaling pathwayPubmed:29510144
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  • Lycium barbarum polysaccharide protects against LPS-induced ARDS by inhibiting apoptosis, oxidative stress, and inflammation in pulmonary endothelial cellsPubmed:29502482
  • Silencing of Girdin suppresses the malignant behavior of colorectal carcinoma cellsPubmed:29989653
  • Decreased miR-128 expression alleviated the progression of Rheumatoid arthritis by up-regulating the expression of TNFAIP3Pubmed:29853534
  • Aspirin modulates the inflammatory response in a thrombus‑stimulated LMVEC modelPubmed:29568915
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  • Chitosan oligosaccharide ameliorates acute lung injury induced by blast injury through the DDAH1/ADMA pathwayPubmed:29415054
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  • PPARγ alleviated hepatocyte steatosis through reducing SOCS3 by inhibiting JAK2/STAT3 pathwayPubmed:29550470
  • Chronic cold exposure results in subcutaneous adipose tissue browning and altered global metabolism in Qinghai-Tibetan plateau pika (Ochotona curzoniae)Pubmed:29626477
  • Tn (-acetyl-d-galactosamine--serine/threonine) immunization protects against hyperoxia-induced lung injury in adult mice through inhibition of the nuclear factor …Pubmed:29669308
  • Shock waves increase pulmonary vascular leakage, inflammation, oxidative stress, and apoptosis in a mouse modelPubmed:29984607
  • Effect of Multi-Microbial Probiotic Formulation Bokashi on Pro-and Anti-Inflammatory Cytokines Profile in the Serum, Colostrum and Milk of Sows, and in a …Pubmed:29305686
  • Uncoupling Protein 2 and Peroxisome Proliferator-Activated Receptor γ Gene Polymorphisms in Association with Diabetes Susceptibility in Chinese Han Population …Pubmed:29849618
  • Pathogen-dependent modulation of milk neutrophils competence, plasma inflammatory cytokines and milk quality during intramammary infection of Sahiwal (Bos …Pubmed:29787791
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  • Rho Kinase Type 1 (ROCK1) Promotes Lipopolysaccharide-induced Inflammation in Corneal Epithelial Cells by Activating Toll-Like Receptor 4 (TLR4) …Pubmed:29804125
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  • Protective effects of sulforaphane on diabetic retinopathy: activation of the Nrf2 pathway and inhibition of NLRP3 inflammasome formationPubmed: 30606939
  • Rebuilding post-infarcted cardiac functions by injecting TIIA@ PDA NPs-crosslinked ROS sensitive hydrogelsPubmed: 30592403
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  • Chandrasekaran Chinampudur Velusami, Edwin Jothie Richard &
  • Long non-coding RNA mitigates atherosclerosis by regulating the actin-binding protein NEXNPubmed: 30589415
  • Honokiol Attenuates Sepsis-Associated Acute Kidney Injury the Inhibition of Oxidative Stress and InflammationPubmed: 30680694
  • Bradykinin contributes to immune liver injury via B2R receptor-mediated pathways in trichloroethylene sensitized mice: a role in Kupffer cell activationPubmed: 30685357
  • Adiponectin attenuates lipopolysaccharide-induced cell injury of H9c2 cells by regulating AMPK pathwayPubmed: 30668810
  • Anti-inflammatory and cognitive effects of interferon-β1a (IFNβ1a) in a rat model of Alzheimer's diseasePubmed: 30777084
  • Transcriptome profiling reveals the anti-diabetic molecular mechanism of Cyclocarya paliurus polysaccharides: Anti-diabetic molecular mechanism of Cyclocarya?…Doi: 10.1016/j.jff.2018.12.039
  • Unfractionated Heparin Alleviates Sepsis-Induced Acute Lung Injury by Protecting Tight JunctionsPubmed: 30771687
  • Synergistic enhancement and hepatoprotective effect of combination of total phenolic extracts of L. and methotrexate for treatment of rheumatoid?…Pubmed: 30729592
  • Rosmarinic acid attenuates inflammatory responses through inhibiting HMGB1/TLR4/NF-κB signaling pathway in a mouse model of Parkinson's disease
  • Astragaloside IV regulates the PI3K/Akt/HO-1 signaling pathway and inhibits H9c2 cardiomyocyte injury induced by hypoxia-reoxygenationPubmed: 30867343
  • Three types of gut bacteria collaborating to improve Kui Jie'an enema treat DSS-induced colitis in micePubmed: 30870717
  • Effect of voluntary running on expression of myokines in brains of rats with depressionPubmed: 30834799
  • Metabolomics analysis of baicalin on ovalbumin-sensitized allergic rhinitis rats
  • Improving the anti-keloid outcomes through liposomes loading paclitaxel–cholesterol complexesPubmed: 30863067
  • Grape seed proanthocyanidin extract alleviates arsenic-induced lung damage through NF-κB signalingPubmed: 30869553
  • Effective Treatment of Bovine Mastitis with Intramammary Infusion of Angelica dahurica and Rheum officinale Extracts
  • Chlorogenic Acid Attenuates Dextran Sodium Sulfate-Induced Ulcerative Colitis in Mice through MAPK/ERK/JNK Pathway
  • Role of melatonin in sleep deprivation‐induced intestinal barrier dysfunction in micePubmed: 30929267
  • Roles of citric acid in conjunction with saline nebulization in experimental tracheostomy in guinea pigsPubmed: 30973274
  • Co-culture of osteochondral explants and synovial membrane as in vitro model for osteoarthritisPubmed: 30939166
  • The wound healing potential of a pro-angiogenic peptide purified from Indian Russell's viper (Daboia russelii) venomPubmed: 31054289
  • Knockdown of periostin attenuates 5/6 nephrectomy‐induced intrarenal renin–angiotensin system activation, fibrosis, and inflammation in rats
  • The role of amniotic fluid exosome, hypoxia inducible fator-1α, and inflammatory cytokine in cervical insufficiency
  • Seluang Fish (Rasbora Spp.) Oil Decreases Inflammatory Cytokines Via Increasing Vitamin D Level in Systemic Lupus Erythematosus
  • miR-21 promotes proliferation and inhibits apoptosis of hepatic stellate cells through targeting PTEN/PI3K/AKT pathwayPubmed: 31038023
  • Intraperitoneal administration of activin A promotes development of endometriotic lesions in a mouse model of endometriosisPubmed: 31064924
  • Total flavonoids from sea buckthorn ameliorates lipopolysaccharide/cigarette smoke‐induced airway inflammationPubmed: 31209984
  • Inflammatory anemia-associated parameters are related to 28-day mortality in patients with sepsis admitted to the ICU: a preliminary observational studyPubmed: 31183575
  • Synergistic effect of sea cucumber saponin and EPA-enriched phospholipids on insulin resistance in high-fat diet-induced obese micePubmed: 31199413
  • Eicosapentaenoic acid in the form of phospholipid exerts superior anti-atherosclerosis effects than its triglyceride form in ApoE-/-mice
  • Expression and Purification of Hybrid LL-37Tα1 Peptide in Pichia pastoris and evaluation of their Immunomodulatory and anti-inflammatory activities by LPS …
  • Network pharmacology oriented study reveals inflammatory state-dependent dietary supplement hepatotoxicity responses in normal and diseased ratsPubmed: 31140472
  • CD28 deficiency attenuates primary blast-induced renal injury in mice via the PI3K/Akt signalling pathwayPubmed: 31129646
  • Lanthanum chloride induces neuron damage by activating the nuclear factor-kappa B signaling pathway in activated microgliaPubmed: 31187842
  • Pinealektomize Edilmiş Septik Sıçanlarda TNF-α, IL-6, IL-10 ve IL-1β'nin Kan Düzeyleri ile Karaciğer ve Böbrekte Gen Ekspresyonu Seviyelerindeki …Doi: 10.5505/vtd.2019.32815
  • Magnetic-responsive and targeted cancer nanotheranostics by PA/MR bimodal imaging-guided photothermally triggered immunotherapy
  • Crosstalk between Cdk5/p35 and ERK1/2 signalling mediates spinal astrocyte activity via the PPARγ pathway in a rat model of chronic constriction injuryPubmed: 31314915
  • STAT3 polymorphisms and IL-6 polymorphism are associated with the risk of basal cell carcinoma in patients from northern PolandPubmed: 31342143
  • Madecassoside ameliorates lipopolysaccharide-induced neurotoxicity in rats by activating the Nrf2-HO-1 pathwayPubmed: 31330225
  • Evaluation of infrared thermography compared to rectal temperature to identify illness in early postpartum dairy cows
  • PD123319, angiotensin II type II receptor antagonist, inhibits oxidative stress and inflammation in 2, 4-dinitrobenzene sulfonic acid-induced colitis in rat and …Pubmed: 31321575
  • Antiallergical Effect of New Combined Nazal Aerodisperse System in the Conditions of Experimental Allergic Rhinitis
  • MODULATION OF LIPOPOLYSACCHARIDE-INDUCED CYTOKINES RESPONSE IN MICE BY GRAVIOLA LEAF POWDER
  • Vitamin D protects against oxidative stress, inflammation and hepatorenal damage induced by acute paracetamol toxicity in ratPubmed: 31255668
  • KLF4 upregulation is involved in alternative macrophage activation during secondary Echinococcus granulosus infectionPubmed: 31407814
  • The effects of hydrogen-rich saline solution on intestinal anastomosis performed after intestinal ischemia reperfusion injury
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  • Metallothionein-1 is associated with osteoarthritis disease activity and suppresses proinflammatory cytokines production in synovial cellsPubmed: 31465913
  • Anti-Inflammatory State in Arabian Horses Introduced to the Endurance TrainingPubmed: 31462005
  • Naoxintong Capsule Inhibits the Development of Cardiovascular Pathological Changes in Bama Minipig Through Improving Gut MicrobiotaPubmed: 31632272
  • Anti-inflammatory and antioxidant effects of muscarinic acetylcholine receptor (mAChR) activation in the rat hippocampusPubmed: 31578381
  • The effects of L-NAME on DU145 human prostate cancer cell line: a cytotoxicity-based studyPubmed: 31610702
  • Polysaccharide from the Seeds of Plantago asiatica L. Protect Against Lipopolysaccharide-Induced Liver InjuryPubmed: 31560611
  • The N-Acetyl Phenylalanine Glucosamine Derivative Attenuates the Inflammatory/Catabolic Environment in a Chondrocyte-Synoviocyte Co-Culture SystemPubmed: 31537813
  • Kappa opioid receptor agonists improve postoperative cognitive dysfunction in rats via the JAK2/STAT3 signaling pathwayPubmed: 31545485
  • Research Article Potential Protective Role of Rutin and Alpha-lipoic Acid Against Cisplatin-induced Nephrotoxicity in RatsPubmed: 31930824
  • INCREASED INTRA-ARTICULAR GRANZYME M TRIGGERS LOCAL PROINFLAMMATORY CYTOKINE RELEASE IN RHEUMATOID ARTHRITISPubmed: 31172927
  • Collaborative Effects of Chlorogenic Acid and Caffeine on Lipid Metabolism via AMPKα-LXRα/SREBP-1c Pathway in High-Fat Diet-Induced Obese MicePubmed: 31670366
  • The immune response of young turkeys to haemorrhagic enteritis virus infection at different levels and sources of methionine in the dietPubmed: 31675966
  • Qingkailing injection ameliorates cerebral ischemia-reperfusion injury and modulates the AMPK/NLRP3 Inflammasome Signalling pathwayPubmed: 31747940
  • Salidroside mitigates skeletal muscle atrophy in rats with cigarette smoke-induced COPD by up-regulating myogenin and down-regulating myostatin expressionPubmed: 31702007
  • Melatonin alleviates oxidative stress in sleep deprived mice: Involvement of small intestinal mucosa injuryPubmed: 31835081
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