Anxiety and Depression Behavioral Experiment Service

Instruction manual

FOR IN VITRO AND RESEARCH USE ONLY
NOT FOR USE IN CLINICAL DIAGNOSTIC PROCEDURES

First Edition (Revised on April, 2016)

Experimental methods	Experimental apparatus	Brief introduction	Application
Elevated plus-maze test	Elevated plus maze	Elevated plus maze is to evaluate the anxiety state of animals, this test is based on animal's characteristics that animal will form a conflict beacause its exploration in new environment and the fear of high open arms.	Elevated plus maze is widely used in scientific research on new drug development, pharmacology, toxicology, preventive medicine, neurobiology, animal psychology.
Tail suspension test	Tail suspension test system	Tail suspension test system is suitable for rat, mouse or other laboratory animals, by fixing the animal tail to make its head hanging down, then record a series of parameters about animals in this environment of a desperate state.	Widely used in primary screening for antidepressants.
the light-dark transition test	the light-dark transition test system	Rodents are inherently uncomfortable with bright lighting areas and have the tendency to explore new environments spontaneously, which making black and white boxes an easy-to-use test instrument without the need for pre-training of animals.	it is widely used in study on learning and memory, Alzheimer's disease, intelligence and aging, new drug development / screening / evaluation, pharmacology, toxicology, preventive medicine, neurobiology, animal psychology and behavioral biology and other disciplines of scientific research.