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ITEM PROTEIN ANTIBODY ASSAY KIT CELL
Cytochrome P450 1A1 (CYP1A1)
CYP1; AHH; AHRR; CP11; CYP1; P1-450; P450-C; P450DX; Cytochrome P450,Subfamily I(Aromatic Compound-Inducible),Polypeptide 1
CYP1A1 is involved in phase I xenobiotic and drug metabolism (one substrate of it is theophylline). It is inhibited by fluoroquinolones and macrolides and induced by aromatic hydrocarbons.
CYP1A1 is also known as AHH (aryl hydrocarbon hydroxylase). It is involved in the metabolic activation of aromatic hydrocarbons (polycyclic aromatic hydrocarbons, PAH), for example, benzopyrene (BP), by transforming it to an epoxide. In this reaction, the oxidation of benzo[a]pyrene is catalysed by CYP1A1 to form BP-7,8-epoxide, which can be further oxidized by epoxide hydrolase (EH) to form BP-7,8-dihydrodiol. Finally CYP1A1 catalyses this intermediate to form BP-7,8-dihydrodiol-9,10-epoxide, which is the ultimate carcinogen.
Organism species: Homo sapiens (Human)
CATALOG NO. PRODUCT NAME
Proteins RPD295Hu01 Recombinant Cytochrome P450 1A1 (CYP1A1) In Stock
Antibodies MAD295Hu21 Monoclonal Antibody to Cytochrome P450 1A1 (CYP1A1) Customize
PAD295Hu01 Polyclonal Antibody to Cytochrome P450 1A1 (CYP1A1) In Stock
Assay Kits SED295Hu ELISA Kit for Cytochrome P450 1A1 (CYP1A1) In Stock
SCD295Hu CLIA Kit for Cytochrome P450 1A1 (CYP1A1) Customize
Organism species: Mus musculus (Mouse)
CATALOG NO. PRODUCT NAME
Proteins RPD295Mu01 Recombinant Cytochrome P450 1A1 (CYP1A1) In Stock
Antibodies PAD295Mu01 Polyclonal Antibody to Cytochrome P450 1A1 (CYP1A1) In Stock
MAD295Mu21 Monoclonal Antibody to Cytochrome P450 1A1 (CYP1A1) Customize
Assay Kits SED295Mu ELISA Kit for Cytochrome P450 1A1 (CYP1A1) Customize
SCD295Mu CLIA Kit for Cytochrome P450 1A1 (CYP1A1) Customize
Organism species: Rattus norvegicus (Rat)
CATALOG NO. PRODUCT NAME
Proteins RPD295Ra01 Recombinant Cytochrome P450 1A1 (CYP1A1) Customize
Antibodies MAD295Ra21 Monoclonal Antibody to Cytochrome P450 1A1 (CYP1A1) Customize
PAD295Ra01 Polyclonal Antibody to Cytochrome P450 1A1 (CYP1A1) Customize
Assay Kits SED295Ra ELISA Kit for Cytochrome P450 1A1 (CYP1A1) In Stock
SCD295Ra CLIA Kit for Cytochrome P450 1A1 (CYP1A1) Customize