Home  |   About us
ITEM PROTEIN ANTIBODY ASSAY KIT CELL
Hypoxanthine Phosphoribosyltransferase 1 (HPRT1)
HGPRT; HPRT; Lesch-Nyhan Syndrome
HPRT1 has a central role in the generation of purine nucleotides through the purine salvage pathway. HPRT1 catalyzes conversion of hypoxanthine to inosine monophosphate and guanine to guanosine monophosphate via transfer of the 5-phosphoribosyl group from 5-phosphoribosyl 1-pyrophosphate. The Lesch-Nyhan syndrome is particularly favorable for this purpose because no affected males reproduce, the diagnosis is unequivocal and cases come readily to attention, and particularly because heterozygosity can be demonstrated in females by the existence of 2 populations of cultured fibroblasts. There were few new mutations, contrary to the expected one-third. On the other hand, about one-half of heterozygous females were new mutations, as is predicted by theory.
Organism species: Homo sapiens (Human)
CATALOG NO. PRODUCT NAME
Proteins RPA717Hu01 Recombinant Hypoxanthine Phosphoribosyltransferase 1 (HPRT1) In Stock
Antibodies MAA717Hu22 Monoclonal Antibody to Hypoxanthine Phosphoribosyltransferase 1 (HPRT1) Customize
PAA717Hu01 Polyclonal Antibody to Hypoxanthine Phosphoribosyltransferase 1 (HPRT1) In Stock
Assay Kits SEA717Hu ELISA Kit for Hypoxanthine Phosphoribosyltransferase 1 (HPRT1) In Stock
SCA717Hu CLIA Kit for Hypoxanthine Phosphoribosyltransferase 1 (HPRT1) Customize
Organism species: Mus musculus (Mouse)
CATALOG NO. PRODUCT NAME
Proteins RPA717Mu01 Recombinant Hypoxanthine Phosphoribosyltransferase 1 (HPRT1) Customize
RPA717Mu02 Recombinant Hypoxanthine Phosphoribosyltransferase 1 (HPRT1) Customize
Antibodies PAA717Mu01 Polyclonal Antibody to Hypoxanthine Phosphoribosyltransferase 1 (HPRT1) Customize
PAA717Mu02 Polyclonal Antibody to Hypoxanthine Phosphoribosyltransferase 1 (HPRT1) Customize
MAA717Mu21 Monoclonal Antibody to Hypoxanthine Phosphoribosyltransferase 1 (HPRT1) Customize
Assay Kits SEA717Mu ELISA Kit for Hypoxanthine Phosphoribosyltransferase 1 (HPRT1) In Stock
SCA717Mu CLIA Kit for Hypoxanthine Phosphoribosyltransferase 1 (HPRT1) Customize
Organism species: Rattus norvegicus (Rat)
CATALOG NO. PRODUCT NAME
Proteins RPA717Ra01 Recombinant Hypoxanthine Phosphoribosyltransferase 1 (HPRT1) Customize
Antibodies PAA717Ra01 Polyclonal Antibody to Hypoxanthine Phosphoribosyltransferase 1 (HPRT1) Customize
MAA717Ra21 Monoclonal Antibody to Hypoxanthine Phosphoribosyltransferase 1 (HPRT1) Customize
Assay Kits SEA717Ra ELISA Kit for Hypoxanthine Phosphoribosyltransferase 1 (HPRT1) Customize
SCA717Ra CLIA Kit for Hypoxanthine Phosphoribosyltransferase 1 (HPRT1) Customize