Recombinant Chemerin (CHEM) Rattus norvegicus (Rat) Recombinant protein

TIG2; RARRES2; Tazarotene-Induced Gene 2; Retinoic Acid Receptor Responder 2,Tazarotene Induced; RAR-responsive protein TIG2

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Overview
Properties
  • Source Prokaryotic expression, Host E.coli
  • Endotoxin Level<1.0EU per 1µg (determined by the LAL method)
  • Subcellular LocationSecreted
  • Molecular Mass 16.1kDa, Accurate 17kDa(Analysis of differences refer to the manual)
  • Residues & TagsSer25~Gly152 with N-terminal His Tag
  • Buffer Formulation20mM Tris, 150mM NaCl, pH8.0, containing 0.01% SKL, 5% Trehalose.
  • Traits Freeze-dried powder, Purity > 90%
  • Isoelectric Point9.0
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  • Recombinant Chemerin (CHEM) Packages (Simulation)
  • Recombinant Chemerin (CHEM) Packages (Simulation)
  • Recombinant Chemerin (CHEM) Figure . Gene Sequencing (extract)
  • RPA945Ra01.jpg SDS-PAGE
  • Certificate ISO9001: 2008, ISO13485: 2003 Registered

Sequence

Usage

Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex.

Storage

Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.

Stability

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Citations

  • Serum chemerin and vaspin in non-alcoholic fatty liver diseasePubMed: 20095887
  • Chemerin, vaspin and insulin resistance in chronic hepatitis CWiley: source
  • Expression and regulation of chemerin during rat pregnancyScienceDirect: S0143400412000902
  • Chronic ethanol consumption increases the levels of chemerin in the serum and adipose tissue of humans and ratsNature: 201211
  • Ankilozan spondilitli hastalarda adipositokin düzeyleri ve insülin direnciRaeddergisi: Source
  • Association of chemerin with oxidative stress, inflammation and classical adipokines in non-diabetic obese patientsPubmed: 24702860
  • Strong correlations between circulating chemerin levels and lipoprotein subfractions in nondiabetic obese and nonobese subjectsPubmed: 24303851
  • Impact of OSA on Biological Markers in Morbid Obesity and Metabolic SyndromePubmed:24106991
  • Chemerin plays a protective role by regulating human umbilical vein endothelial cell-induced nitric oxide signaling in preeclampsiaPubmed:24840719
  • Relationship between plasma chemerin levels and disease severity in COPD patientsPubmed:24865134
  • Elevated serum chemerin in Chinese women with hyperandrogenic PCOSPubmed:24927079
  • Protective effect of liraglutide against ER stress in the liver of high-fat diet-induced insulin-resistant rats.Pubmed:25471281
  • Long-term Effect of Ileal Transposition on Adipokine Serum Level in Zucker (Orl)-Lepr fa Fatty RatsPubmed:25697126
  • Chemerin and calprotectin levels correlate with disease activity and inflammation markers in psoriasis vulgarisSciencedirect:S1027811714000470
  • Serum Chemerin Levels in relation to Osteoporosis and Bone Mineral Density: A Case-Control StudyPubMed: 26170530
  • Association of Serum Chemerin Levels with Acute Ischemic Stroke and Carotid Artery Atherosclerosis in a Chinese PopulationPubMed: 26471865
  • Protective effect of liraglutide against ER stress in the liver of high-fat diet-induced insulin-resistant ratsPubMed: 25471281
  • Effects of alpha-lipoic acid on chemerin secretion in 3T3-L1 and human adipocytesPubmed:26721419
  • Association of chemerin levels and bone mineral density in Chinese obese postmenopausalwomen.pubmed:27583869
  • Changes of Plasma FABP4, CRP, Leptin, and Chemerin Levels in relation to Different Dietary Patterns and Duodenal-Jejunal Omega Switch Surgery in Sprague …Pubmed:29849871
  • Chemerin is associated with diabetic retinopathy in type 2 diabetesPubmed:25848840
  • Expression of chemerin in the synovial fluid of patients with temporomandibular joint disordersPubmed:29331039
  • Epigenetic regulation of Amphiregulin and Epiregulin in colorectal cancerPubmed: 30252132
  • The decline of whole-body glucose metabolism in ovariectomized ratsPubmed: 30292771
  • Chemerin alleviates acute pancreatitis in the rat thorough modulation of NF-κB signalDoi: 10.1016/j.pan.2019.02.005
  • Protective effect of vitamin D supplementation in a rat modal of preeclampsia: a possible implication of chemerinPubmed: 30922121
  • Chemerin alleviates acute pancreatitis in the rat thorough modulation of NF-kB signalPubmed: 30833212
  • Association between High Levels of Circulating Chemerin and Colorectal Adenoma in MenPubmed: 31269491
  • Vitamin D Supplementation Reduces Serum Chemerin Level in Gestational Diabetes Mellitus Rat Model
  • Plasma levels of adiponectin and chemerin are associated with early stage of atherosclerosis in older adults with type 2 diabetes mellitus
  • The dietary inflammatory index is associated with anti-and pro-inflammatory adipokines in Brazilian schoolchildren33575861
  • Pro-and anti-inflammatory adipokines are associated with cardiometabolic risk markers in Brazilian schoolchildren33834274
  • Altered Serum Marker of Adipokines Profile in Breast Cancer Women
  • Association of High Serum Chemerin with Bone Mineral Density Loss and Osteoporotic Fracture in Elderly Chinese WomenPubmed:35140527

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