Recombinant Complement Factor I (CFI)

CF-I; C3b-INA; FI; IF; KAF; Factor I; Konglutinogen-Activating Factor; C3b-Inactivator; C3B/C4B inactivator

UOM
1. 10µg
2. 50µg
3. 200µg
4. 1mg
5. 5mg
FOB US$ 172.00 US$ 430.00 US$ 860.00 US$ 2,580.00 US$ 6,450.00
Quantity

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Overview

Properties

Product No.RPB978Hu01
Organism SpeciesHomo sapiens (Human) Same name, Different species.
- All
- Human
- Mouse
- Rat
- Cavia
- Rabbit
- Simian
- Canine
- Porcine
- Bovine
- Caprine
- Multi-species
- Pan-species
- Others
Applications Positive Control; Immunogen; SDS-PAGE; WB.
If bio-activity of the protein is needed, please check active protein.
Research use only
DownloadInstruction Manual
CategoryMetabolic pathway Immune molecule Hematology Autoimmunity

Source Prokaryotic expression, Host E.coli
Endotoxin Level<1.0EU per 1µg (determined by the LAL method)
Subcellular LocationSecreted, Extracellular matrix
Molecular Mass 28.8kDa, Accurate 30kDa(Analysis of differences refer to the manual)
Residues & TagsIle340~Val583 with N-terminal His Tag
Buffer Formulation20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300.
Traits Freeze-dried powder, Purity > 97%
Isoelectric Point6.4

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Packages (Simulation)
Packages (Simulation)

SDS-PAGE

ISO9001: 2008, ISO13485: 2003 Registered

Sequence

Usage

Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex.

Storage

Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.

Stability

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Giveaways

Polyacrylamide Gel Electrophoresis (PAGE) Experiment Service

Increment services

Citations

A case report of thrombotic microangiopathy without renal involvement carrying two novel mutations in complement-regulator genesPubMed: 26613809
Atypical hemolytic uremic syndrome: Korean pediatric seriesPubMed: 25443527
NOVEL ASSAYy2016:139118
Compliment factor i bioassayUS20170285024
A monoclonal antibody targeting amyloid β (Aβ) restores complement factor I bioactivity: Potential implications in age-related macular degeneration and …Pubmed:29782502
The importance of sialic acid, pH and ion concentration on the interaction of uromodulin and complement factor H33788378