Recombinant Corticosteroid Binding Globulin (CBG) Rattus norvegicus (Rat) Recombinant protein

SERPINA6; Transcortin; Serpin A6; Serpin Peptidase Inhibitor,Clade A,Member 6(Alpha-1 Antiproteinase; Antitrypsin)

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Overview
Properties
  • Source Prokaryotic expression, Host E.coli
  • Endotoxin Level<1.0EU per 1µg (determined by the LAL method)
  • Subcellular LocationSecreted
  • Molecular Mass 13.3kDa, Accurate 13kDa(Analysis of differences refer to the manual)
  • Residues & TagsAla35~Lys140 (Accession # P31211) with N-terminal His Tag
  • Buffer FormulationPBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
  • Traits Freeze-dried powder, Purity > 97%
  • Isoelectric Point6.1
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  • Recombinant Corticosteroid Binding Globulin (CBG) Packages (Simulation)
  • Recombinant Corticosteroid Binding Globulin (CBG) Packages (Simulation)
  • RPB226Ra01.jpg SDS-PAGE
  • Certificate ISO9001: 2008, ISO13485: 2003 Registered

Sequence

Usage

Reconstitute in 10mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Do not vortex.

Storage

Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.

Stability

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Citations

  • The Regulation of Rasd1 Expression by Glucocorticoids and Prolactin Controls Peripartum Maternal Insulin SecretionEndjournals: Source
  • Modulation in Wistar Rats of Blood Corticosterone Compartmentation by Sex and a Cafeteria DietPubMed: PMC3579843
  • Differences in colocalization of corticosteroid-binding globulin and glucocorticoid receptor immunoreactivity in the rat brainScienceDirect: S0940960212001628
  • Adrenocortical control in the neonatal rat: ACTH‐and cAMP‐independent corticosterone production during hypoxiaPubmed: 24303136
  • Adrenocorticotropic Hormone But Not High-Density Lipoprotein Cholesterol or Salivary Cortisol Was a Predictor of Adrenal Insufficiency in Patients With Septic Shock.Pubmed: 24667620
  • Greater glucocorticoid receptor activation in hippocampus of aged rats sensitizes microgliaPubmed:25559333
  • Novel p53 target genes secreted by the liver are involved in non-cell-autonomous reCavia (Guinea pig )lationPubmed:26358154
  • Impact of Season and Oral Contraceptive use on Cortisol Levelsin Physically Active Womenexercise-sports-orthopedics:exercise-sports-orthop
  • Impact of Season and Oral Contraceptive use on Cortisol Levels in Physically Active Womendiva2:1047030
  • Impaired glucocorticoid-mediated HPA axis negative feedback induced by juvenile social isolation in male ratsPubmed:29407214
  • The impact of early-life stress on corticosteroid carrier protein levels and 11β-hydroxysteroid dehydrogenase 1 expression in adolescent rats

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