Eukaryotic Interleukin 2 (IL2) Mus musculus (Mouse) Eukaryotic protein

TCGF; Lymphokine; T-Cell Growth Factor; Aldesleukin

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Overview
Properties
  • Source Eukaryotic expression, Host 293F cell
  • Endotoxin Level<1.0EU per 1µg (determined by the LAL method)
  • Subcellular LocationSecreted
  • Molecular Mass 18.9kDa, Accurate 25kDa(Analysis of differences refer to the manual)
  • Residues & TagsAla21~Gln169 with N-terminal His Tag
  • Buffer Formulation20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 5% Trehalose and Proclin300.
  • Traits Freeze-dried powder, Purity > 97%
  • Isoelectric Point4.9
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  • Eukaryotic Interleukin 2 (IL2) Packages (Simulation)
  • Eukaryotic Interleukin 2 (IL2) Packages (Simulation)
  • Eukaryotic Interleukin 2 (IL2) Gene sequencing
  • EPA073Mu61.jpg SDS-PAGE
  • Certificate ISO9001: 2008, ISO13485: 2003 Registered

Sequence

Usage

Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0
mg/mL. Do not vortex

Storage

Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.

Stability

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Citations

  • Evaluation of water plantain (Alisma canaliculatum A. Br. et Bouche) and mistletoe (Viscum album L.) effects on broiler growth performance, meat composition and serum biochemical parametersAcadeMic: source
  • Synthesis and inflammatory response of a novel silk fibroin scaffold containing BMP7 adenovirus for bone regenerationPubMed: 22796416
  • Efficient intracellular delivery of siRNA with a safe multitargeted lipid-based nanoplatformPubMed: 23394132
  • Identification and functional characterization of a novel fungal immunomodulatory protein from Postia placentaPubmed:25662032
  • Molecular Mechanisms of the Modulatory Effect of Vitamin E on Tacrolimus (FK506)-Induced Renal Injury in RatsOpenview: 6Ba34F298130121B36Fc3E227Ed416F4
  • Efficacy of Albendazole-Chitosan Microsphere-based Treatment for Alveolar Echinococcosis in MicePubMed: 26352932
  • Berberine alleviates preeclampsia possibly by regulating the expression of interleukin-2/interleukin-10 and Bcl-2/BaxPubMed: 26629148
  • Can apical periodontitis affect serum levels of CRP, IL-2, and IL-6 as well as induce pathological changes in remote organs?PubMed: 26556576
  • Evaluation of proliferation and cytokines production by mitogen-stimulated bovine peripheral blood mononuclear cellsArticle_14936_6.Html:
  • Molecular mechanisms of the protective role of wheat germ oil against cyclosporin A-induced hepatotoxicity in ratsPubMed: 25858514
  • Mesenchymal stromal cell-dependent reprogramming of Kupffer cells is mediated by TNF-α and PGE10 and is crucial for liver transplant tolerancePubMed: 25982596
  • The immunomodulating effect of seminal plasma on T cellsPubMed: 25799173
  • ЦитокCgi-Bin: Irbis_Nbuv
  • Clinical significance of IL-2 and IL-10 gene polymorphisms and serum levels in patients with basal-cell carcinomaPubMed: 26609634
  • Ameliorative effect of flaxseed oil against thiacloprid-induced toxicity in rats: hematological, biochemical, and histopathological studyPubmed:26957428
  • Antiinflammatory Effect of N-Acetylcysteine Combined with Exogenous Surfactant in Meconium-Induced Lung InjuryPubmed:27283193
  • Effects of feed supplementation with glycine chelate and iron sulfate on selected parameters of cell-mediated immune response in broiler chickensPubmed:27473977
  • Investigation of the anti-glioma activity of Oviductus ranae protein hydrolysatePubmed:27261592
  • International Journal of Pharma and Bio Sciences ISSNcms:4987
  • INFLUENCE OF ZINCOVIT DROP (NUTRITIONAL FOOD SUPPLEMENT) ON IMMUNE SYSTEM IN NORMAL AND CYCLOPHOSPHAMIDE INTOXICATED WISTAR RATSjournals:3790
  • HERPES VIRUS VACCINES AND TREATMENTSy2016:0067330.html
  • Lymphocytic, cytokine and transcriptomic profiles in peripheral blood of dogs with atopic dermatitispubmed:27553600
  • Efficacy of an autophagy-targeted DNA vaccine against avian leukosis virus subgroup J.pubmed:28049588
  • Influences of Hyriopsis cumingii polysaccharides on mice immunosignaling molecules and T lymphocyte differentiation09540105.2017.1306494
  • Lung inflammatory and oxidative alterations after exogenous surfactant therapy fortified with budesonide in rabbit model of meconium aspiration syndrome.pubmed:28006947
  • Characterization of Simian Immunodeficiency Virus Variants Anatomically Compartmentalized inPlasma and Milk in Chronically Infected African Green Monkeys.pubmed:
  • The effect of feed supplementation with zinc chelate and zinc sulphate on selected humoral and cell-mediated immune parameters and cytokine concentration in …S0034528816303162
  • Commercial gold nanocolloid inhibits synthesis of IL-2 and proliferation of porcine T lymphocytesscience:article
  • Imbalance of intestinal immune function in piglets infected by porcine circovirus type 2 during the fetal period.pubmed:28244338
  • ВПЛИВ КРОВОВТРАТИ НА ДИНАМІКУ ВМІСТУ ЦИТОКІНІВ СИРОВАТКИ КРОВІ В ПЕРІОД ГОСТРОЇ РЕАКЦІЇ НА КРАНІОСКЕЛЕТНУ ТРАВМУ83646
  • Effect of boron on thymic cytokine expression, hormone secretion, antioxidant functions, cell proliferation, and apoptosis potential via the ERK1/2 signaling pathwaypubmed:29032684
  • The effect of feed supplementation with effective microorganisms(EM) on pro- and anti-inflammatory cytokine concentrations in pigspubmed:28549299
  • The effect of feed supplementation with Zakarpacki zeolite (clinoptilolite) on percentages of T and B lymphocytes and cytokine concentrations in poultrypubmed:28339915
  • The effect of feed supplementation with a copper-glycine chelate and copper sulphate on selected humoral and cell-mediated immune parameters, plasma superoxide dismutase activity, ceruloplasmin and cytokine concentration in broiler chickensdoi:10.1111
  • Interleukin-17 antagonist attenuates lung inflammation through inhibition of the ERK1/2 and NF-κB pathway in LPS-induced acute lung injury10.3892/mmr.2017.6837
  • A bacterial ghost improves the immunological efficacy of a Newcastle disease virus inactivated vaccinepubmed:28619143
  • EGCG Maintains Th1/Th2 Balance and Mitigates Ulcerative Colitis Induced by Dextran Sulfate Sodium through TLR4/MyD88/NF-ݜ傠Signaling Pathway in Rats10.1155/2017/3057268
  • Integrated effect of seasons and lactation stages on the plasma inflammatory cytokines, function and receptor expression of milk neutrophils in Sahiwal (Bos indicus) cows.pubmed:28895861
  • A study of altered cytokine rhythms associated with successful implantation in cows10.1080/09291016.2017.1361159
  • Sex differences in complex regional pain syndrome type I (CRPS-I) in micepubmed:28831269
  • EGCG Maintains Th1/Th2 Balance and Mitigates Ulcerative Colitis Induced by Dextran Sulfate Sodium through TLR4/MyD88/NF-κB Signaling Pathway in Rats10.1155/2017/3057268
  • In Vivo Study on the Hindrance Activity of Cinnamon Extract Against Aspergillus niger in MiceISSN: 0974-4290
  • Sonodynamic therapy‐assisted immunotherapy: A novel modality for cancer treatmentPubmed:29575297
  • Cyclosporine a drug-delivery system for high-risk penetrating keratoplasty: Stabilizing the intraocular immune microenvironmentPubmed:29734357
  • Effect of Multi-Microbial Probiotic Formulation Bokashi on Pro-and Anti-Inflammatory Cytokines Profile in the Serum, Colostrum and Milk of Sows, and in a …Pubmed:29305686
  • Pathogen-dependent modulation of milk neutrophils competence, plasma inflammatory cytokines and milk quality during intramammary infection of Sahiwal (Bos …Pubmed:29787791
  • Effect of tropical thermal stress on peri-implantation immune responses in cowsPubmed:29625402
  • Immunomodulatory activity of Lactobacillus plantarum KLDS1. 0318 in cyclophosphamide-treated micePubmed:30026678
  • The effect of feed supplementation with a copper‐glycine chelate and copper sulphate on selected humoral and cell‐mediated immune parameters, plasma …Pubmed:28603872
  • Changes in Th1/Th2-producing cytokines during acute exacerbation chronic obstructive pulmonary diseasePubmed:29950127
  • Effectiveness of steamed and cooked broccoli to attenuate bone marrow injury and suppressed haemopoiesis in male rats exposed to petrol vapours10.1080:00207233.2018.1502956
  • Evaluation of T regulatory lymphocytes and serum concentration of selected cytokines in dogs with perianal tumors
  • Vitamin E inhibits cyclosporin A-induced CTGF and TIMP-1 expression by repressing ROS-mediated activation of TGF-β/Smad signaling pathway in rat liverPubmed: 30391882
  • Early cytokine response after vaccination with Coxiella burnetii phase I in an infected herd of dairy cattle
  • Amlexanox attenuates experimental autoimmune encephalomyelitis by inhibiting dendritic cell maturation and reprogramming effector and regulatory T cell …Pubmed: 30823934
  • CD56 natural killer cells exhibit abnormal phenotype and function in severe aplastic anemia
  • Ginsenoside Rg3 improves cyclophosphamide-induced immunocompetence in Balb/c micePubmed: 30974284
  • TRAF-6 调控TGF-β1-Smad2/Smad3 信号通路在Graves 病免疫发病机制中的作用
  • Anti-Inflammatory State in Arabian Horses Introduced to the Endurance TrainingPubmed: 31462005
  • Polysaccharide from the Seeds of Plantago asiatica L. Protect Against Lipopolysaccharide-Induced Liver InjuryPubmed: 31560611
  • The therapeutic effect of dendritic cells expressing indoleamine 2, 3-dioxygenase (IDO) on an IgA nephropathy mouse modelPubmed: 31894556
  • Pathogenicity of porcine reproductive and respiratory syndrome virus (ORF5 RFLP 1–7–4 viruses) in ChinaPubmed: 32187856
  • The toxicity of alumina nanoparticles to immune system in micePubmed: 32162999
  • Cordycepin exhibits a suppressive effect on T cells through inhibiting TCR signaling cascade in CFA-induced inflammation mice modelPubmed: 32105161
  • Suppressor of ras val-2 promotes inflammation-mediated oxidative stress and cell apoptosis in cardiomyocytes through activating Mst1-mROS signaling pathwayPubmed: 32065019
  • Effects of Early Intervention with Antibiotics and Maternal Fecal Microbiota on Transcriptomic Profiling Ileal Mucusa in Neonatal PigsPubmed: 31963653
  • Effects of tetrahedral framework nucleic acid/wogonin complexes on osteoarthritisPubmed: 32047705
  • Active metronomic vinorelbine schedules decrease plasma interleukin-2 levels in mice with Lewis lung carcinomaPubmed: 32930084
  • Porcine soluble CD83 alleviates LPS-induced abortion in mice by promoting Th2 cytokine production, Treg cell generation and trophoblast invasionPubmed: 32810792
  • A comparative study on various immunological parameters influencing embryo survivability in crossbred dairy cowsPubmed: 32810791
  • Impact of diminazene aceturate on renin-angiotensin system, infectious myocarditis and skeletal myositis in mice: An in vitro and in vivo studyPubmed: 32652140
  • Association Between Serum Selenium Level and Subclinical Mastitis in Dairy CattlePubmed: 32583225
  • IMMUNOSTIMULATORY EFFECT OF MORINGA OLEIFERA LEAVES EXTRACT ON CYCLOPHOSPHAMIDE-INDUCED IMMUNOSUPPRESSION IN MICE
  • Tissue-Engineered Decellularized Allografts for Anterior Cruciate Ligament Reconstruction
  • Immunomodulatory effects of sCD83 via induction of TGF-β1 and IDO: an in vitro and rat orthotopic liver transplantation study
  • Hormonal and Cytokine Blood Profile of Dairy Cows in the Early Gestation Period
  • THE CHANGE OF INDICATORS OF PROTEIN, LIPID AND CARBOHYDRATE METABOLISM IN DAIRY COWS AFTER CALVING DURING THE FORMATION OF …
  • Effect of alfalfa hay and starter feed supplementation on caecal microbiota and fermentation, growth, and health of yak calves33610512
  • Salivary Irisin: potential inflammatory biomarker in recurrent apthous stomatitis patients33755963
  • Orexin A Suppresses the Expression of Exosomal PD-L1 in Colon Cancer and Promotes T Cell Activity by Inhibiting JAK2/STAT3 Signaling Pathway34097168
  • How Does the Th1/Th2 Polarization in Milk Change According to the Types of Bacteria that Cause Subclinical Mastitis in Cows?
  • Experimental autoimmune encephalomyelitis inhibited by Huangqi Guizhi Wuwu Decoction via Th2 cytokine enhancement
  • Immunostimulatory Effect of Moringa oleifera Extracts on Cyclophosphamide-induced Immunosuppressed Mice
  • Combined treatment with epigenetic agents enhances anti-tumor activity of T cells by upregulating the ACRBP expression in hepatocellular carcinoma34377237
  • Inhibition of NF-κB/IL-33/ST2 Axis Ameliorates Acute Bronchiolitis Induced by Respiratory Syncytial Virus34395633
  • Autonomic regulation of imbalance‑induced myocardial fibrosis and its mechanism in rats with cirrhosis34373726
  • Interleukin-10-Mediated Lymphopenia Caused by Acute Infection with Foot-and-Mouth Disease Virus in Mice34960627
  • Optimizing the growth and immune system of dairy calves by subdividing the pre-weaning period and providing different milk volumes for each stage34786502
  • Anti‐PD‐L1/TGF‐βR fusion protein (SHR‐1701) overcomes disrupted lymphocyte recovery‐induced resistance to PD‐1/PD‐L1 inhibitors in lung cancerPubmed:34981670
  • NLRP3 Inflammasome Activation Controls Vascular Smooth Muscle Cells Phenotypic Switch in AtherosclerosisPubmed:35008765
  • A randomized controlled trial evaluating the effect of two low-level laser irradiation protocols on the rate of canine retractionPubmed:35710926
  • Construction of a rabbit model with vinorelbine administration via peripherally inserted central catheter and dynamic monitoring of changes in phlebitis and thrombosisPubmed:35126715
  • Alleviation of chemotherapy-induced acute lung injury via NLRP3/ASC/Caspase-1 signaling pathwayPubmed:35782645
  • Age-Dependent Dynamics of Maternally Derived Antibodies (MDAs) and Understanding MDA-Mediated Immune Tolerance in Foot-and-Mouth Disease-Vaccinated …Pubmed:35632433
  • Th1/Th2 cytokine polarization in milk according to different pathogens causing subclinical mastitis in cows

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