Recombinant Interferon Gamma Induced Protein 10kDa (IP10) Mus musculus (Mouse) Recombinant protein

CXCL10; C7; IFI10; INP10; SCYB10; Crg2; GIP10; Mob1; Chemokine C-X-C Motif Ligand 10; Small Inducible Cytokine Subfamily B(Cys-X-Cys)Member 10

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Overview
Properties
  • Source Prokaryotic expression, Host E.coli
  • Endotoxin Level<1.0EU per 1µg (determined by the LAL method)
  • Subcellular LocationSecreted
  • Molecular Mass 12.5kDa, Accurate 15kDa(Analysis of differences refer to the manual)
  • Residues & TagsIle22~Pro98 with N-terminal His Tag
  • Buffer Formulation20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300.
  • Traits Freeze-dried powder, Purity > 95%
  • Isoelectric Point10.2
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  • Recombinant Interferon Gamma Induced Protein 10kDa (IP10) Packages (Simulation)
  • Recombinant Interferon Gamma Induced Protein 10kDa (IP10) Packages (Simulation)
  • RPA371Mu01.jpg SDS-PAGE
  • Certificate ISO9001: 2008, ISO13485: 2003 Registered

Sequence

Usage

Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex.

Storage

Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.

Stability

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Citations

  • Melatonin inhibits type 1 interferon signaling of toll-like receptor 4 via heme oxygenase-1 induction in hepatic ischemia/reperfusion.PubMed: 22288937
  • Maternal circulating leukocytes display early chemotactic responsiveness during late gestationPubMed: PMC3561147
  • Serum levels of selected chemokines in systemic lupus erythematosus patientsPubmed: 22461186
  • The Immunosuppressant Protosappanin A Diminished Recipient T Cell Migration into Allograft via Inhibition of IP-10 in Rat Heart TransplantPubmed:24798458
  • The G-Protein-Coupled Bile Acid Receptor Gpbar1 (TGR5) Inhibits Gastric Inflammation Through Antagonizing NF-κB Signaling PathwayPubMed: 26696888
  • Hypoxia/ischemia promotes CXCL10 expression in cardiac microvascular endothelial cells by NFkB activationPubmed:26891076
  • LPS alters the immuno-phenotype of glioma and glioma stem-like cells and induces in vivo antitumor immunity via TLR4.pubmed:28641579
  • Serum biomarkers for predicting overall survival and early mortality in older patients with metastatic solid tumorsPubmed: 30952517
  • Integrated Omics Reveals Tollip as an Aggravator and Therapeutic Target for Hepatic Ischemia‐Reperfusion Injury in MicePubmed: 31077413
  • IL‑17A promotes CXCR2‑dependent angiogenesis in a mouse model of liver cancerPubmed: 31173199
  • Inflammatory Responses of Astrocytes Are Independent from Lipocalin 2Pubmed: 32959226

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