Monoclonal Antibody to A Disintegrin And Metalloprotease 17 (ADAM17)

CD156b; TACE; CSVP; Tumor Necrosis Factor,Alpha,Converting Enzyme; Disintegrin and metalloproteinase domain-containing protein 17; Snake venom-like protease

UOM
1. 20µl
2. 100µl
3. 200µl
4. 1ml
5. 10ml
FOB US$ 87.00 US$ 203.00 US$ 290.00 US$ 725.00 US$ 2,900.00
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Overview

Properties

Product No.MAB555Hu22
Organism SpeciesHomo sapiens (Human) Same name, Different species.
- All
- Human
- Mouse
- Rat
- Cavia
- Rabbit
- Simian
- Canine
- Porcine
- Bovine
- Caprine
- Multi-species
- Pan-species
- Others
ApplicationsWB; IHC
If the antibody is used in flow cytometry, please check FCM antibodies.
Research use only
DownloadInstruction Manual
CategoryEnzyme & Kinase Tumor immunity

SourceMonoclonal antibody preparation, Host Mouse
Ig Isotype IgG2b Kappa, Clone Number C7
PurificationProtein A + Protein G affinity chromatography
LabelNone
Immunogen RPB555Hu01-Recombinant A Disintegrin And Metalloprotease 17 (ADAM17)
Buffer FormulationPBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
TraitsLiquid, Concentration 1mg/ml

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Packages (Simulation)
Packages (Simulation)

DAB staining on IHC-P; Samples: Human Prostate cancer Tissue; Primary Ab: 30µg/ml Mouse Anti-Human ADAM17 Antibody Second Ab: 2µg/mL HRP-Linked Caprine Anti-Mouse IgG Polyclonal Antibody (Catalog: SAA544Mu19)
DAB staining on IHC-P;
Samples: Human Skin cancer Tissue;
Primary Ab: 30µg/ml Mouse Anti-Human ADAM17 Antibody
Second Ab: 2µg/mL HRP-Linked Caprine Anti-Mouse IgG Polyclonal Antibody
(Catalog: SAA544Mu19)
DAB staining on IHC-P;
Samples: Human Cerebrum Tissue;
Primary Ab: 30µg/ml Mouse Anti-Human ADAM17 Antibody
Second Ab: 2µg/mL HRP-Linked Caprine Anti-Mouse IgG Polyclonal Antibody
(Catalog: SAA544Mu19)
DAB staining on IHC-P;
Samples: Human Liver cancer Tissue;
Primary Ab: 30µg/ml Mouse Anti-Human ADAM17 Antibody
Second Ab: 2µg/mL HRP-Linked Caprine Anti-Mouse IgG Polyclonal Antibody
(Catalog: SAA544Mu19)
DAB staining on IHC-P;
Samples: Human Liver Tissue;
Primary Ab: 30µg/ml Mouse Anti-Human ADAM17 Antibody
Second Ab: 2µg/mL HRP-Linked Caprine Anti-Mouse IgG Polyclonal Antibody
(Catalog: SAA544Mu19)
DAB staining on IHC-P;
Samples: Human Stomach cancer Tissue;
Primary Ab: 30µg/ml Mouse Anti-Human ADAM17 Antibody
Second Ab: 2µg/mL HRP-Linked Caprine Anti-Mouse IgG Polyclonal Antibody
(Catalog: SAA544Mu19)

Figure. Western Blot; Sample: Recombinant ADAM17, Human.

ISO9001: 2008, ISO13485: 2003 Registered

Specifity

The antibody is a mouse monoclonal antibody raised against ADAM17. It has been selected for its ability to recognize ADAM17 in immunohistochemical staining and western blotting.

Usage

Western blotting: 0.01-3µg/mL;
Immunohistochemistry: 5-30µg/mL;
Optimal working dilutions must be determined by end user.

Storage

Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

Stability

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Organism Species More: Mus musculus (Mouse), Rattus norvegicus (Rat)

Giveaways

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Citations

From varices to venous ulceration: the story of chronic venous disease described by metalloproteinases.Pubmed:26991748
From varices to venous ulceration: the story of chronic venous disease described by metalloproteinasespubmed:26991748
ADAM17 regulates TNF-α expression upon lipopolysaccharide stimulation in oral keratinocytes.pubmed:28637950
L‐Selectin Expression Is Influenced by Phosphatase Activity in Chronic Lymphocytic LeukemiaPubmed: 30729673
Adamalysines as Biomarkers and a Potential Target of Therapy in Colorectal Cancer Patients: Preliminary ResultsPubmed: 31565100
PEG-SOD attenuates the mitogenic ERK1/2 signaling cascade induced by cyclosporin A in the liver and kidney of albino micePubmed: 32866465
High Levels of TNF-¦Á and TIM-3 as a Biomarker of Immune Reconstitution Inflammatory Syndrome in People with HIV Infection