Polyclonal Antibody to A Disintegrin And Metalloprotease 28 (ADAM28) Homo sapiens (Human) Polyclonal antibody

ADAM23; MDCL; eMDCII; Metalloproteinase-like, disintegrin-like, and cysteine-rich protein L; Epididymal metalloproteinase-like, disintegrin-like, and cysteine-rich protein II

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Overview
Properties
  • SourcePolyclonal antibody preparation, Host Rabbit
  • Ig Type IgG, Potency n/a
  • PurificationAntigen-specific affinity chromatography followed by Protein A affinity chromatography
  • LabelNone
  • Immunogen RPK202Hu01-Recombinant A Disintegrin And Metalloprotease 28 (ADAM28)
  • Buffer FormulationPBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
  • TraitsLiquid, Concentration 500µg/mL
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  • Polyclonal Antibody to A Disintegrin And Metalloprotease 28 (ADAM28) Packages (Simulation)
  • Polyclonal Antibody to A Disintegrin And Metalloprotease 28 (ADAM28) Packages (Simulation)
  • Polyclonal Antibody to A Disintegrin And Metalloprotease 28 (ADAM28) IHC Images
  • PAK202Hu01.jpg WB Image
  • Certificate ISO9001: 2008, ISO13485: 2003 Registered

Specifity

The antibody is a rabbit polyclonal antibody raised against ADAM28. It has been selected for its ability to recognize ADAM28 in immunohistochemical staining and western blotting.

Usage

Western blotting: 0.5-2µg/mL;
Immunohistochemistry: 5-20µg/mL;
Immunocytochemistry: 5-20µg/mL;
Optimal working dilutions must be determined by end user.

Storage

Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

Stability

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Giveaways

Citations

  • Urinary protein profiling by liquid chromatography/tandem mass spectrometry: ADAM28 is overexpressed in bladder transitional cell carcinomaPubmed: 21913264
  • Baseline and decline of serum ADAM28 during chemotherapy of advanced non-small cell lung cancer: a probable predictive and prognostic factorSpringerLink: kg628446760r60rl
  • ADAM28 is elevated in humans with the metabolic syndrome and is a novel sheddase of human tumour necrosis factor-α.PubMed: 23010875
  • ADAM28 overexpression regulated via the PI3K/Akt pathway is associated with relapse inPubMed: 26340916
  • Adamalysines as Biomarkers and a Potential Target of Therapy in Colorectal Cancer Patients: Preliminary ResultsPubmed: 31565100

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