• KO-Validated
Polyclonal Antibody to Glutathione Reductase (GR) Homo sapiens (Human) Polyclonal antibody

GSR; GLUR; GRD1; Glutathione reductase, mitochondrial

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Overview
Properties
  • SourcePolyclonal antibody preparation, Host Rabbit
  • Ig Type IgG, Potency n/a
  • PurificationAntigen-specific affinity chromatography followed by Protein A affinity chromatography
  • LabelNone
  • Immunogen RPB314Hu01-Recombinant Glutathione Reductase (GR)
  • Buffer Formulation0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
  • TraitsLiquid, Concentration 0.5mg/ml
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  • Polyclonal Antibody to Glutathione Reductase (GR) Packages (Simulation)
  • Polyclonal Antibody to Glutathione Reductase (GR) Packages (Simulation)
  • Polyclonal Antibody to Glutathione Reductase (GR) DAB staining on IHC-P; Samples: Human Liver Tissue; Primary Ab: 20µg/ml Rabbit Anti-Human GR Antibody Second Ab: 2µg/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody (Catalog: SAA544Rb19)
  • Polyclonal Antibody to Glutathione Reductase (GR) DAB staining on IHC-P;
    Samples: Human Prostate Tissue;
    Primary Ab: 20µg/ml Rabbit Anti-Human GR Antibody
    Second Ab: 2µg/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody
    (Catalog: SAA544Rb19)
  • Polyclonal Antibody to Glutathione Reductase (GR) DAB staining on IHC-P;
    Samples: Human Kidney Tissue;
    Primary Ab: 20µg/ml Rabbit Anti-Human GR Antibody
    Second Ab: 2µg/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody
    (Catalog: SAA544Rb19)
  • Polyclonal Antibody to Glutathione Reductase (GR) DAB staining on IHC-P;
    Samples: Human Pancreas Tissue;
    Primary Ab: 20µg/ml Rabbit Anti-Human GR Antibody
    Second Ab: 2µg/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody
    (Catalog: SAA544Rb19)
  • Polyclonal Antibody to Glutathione Reductase (GR) DAB staining on IHC-P;
    Samples: Human Breast cancer Tissue;
    Primary Ab: 20µg/ml Rabbit Anti-Human GR Antibody
    Second Ab: 2µg/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody
    (Catalog: SAA544Rb19)
  • Polyclonal Antibody to Glutathione Reductase (GR) DAB staining on IHC-P;
    Samples: Human Prostate cancer Tissue;
    Primary Ab: 20µg/ml Rabbit Anti-Human GR Antibody
    Second Ab: 2µg/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody
    (Catalog: SAA544Rb19)
  • PAB314Hu01.jpg Figure. Western Blot; Sample: Recombinant GR, Human.
  • Polyclonal Antibody to Glutathione Reductase (GR) Western Blot; Sample: Lane1: Human Liver lysate; Lane2: Human Lung lysate; Lane3: Hela cell lysate
    Primary Ab: 3ug/ml Rabbit Anti-Human GR Antibody
    Second Ab: 0.2µg/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody
    (Catalog: SAA544Rb19)
  • Polyclonal Antibody to Glutathione Reductase (GR) Knockout Varification:
    Lane 1: Wild-type Hela cell lysate;
    Lane 2: GR knockout Hela cell lysate;
    Predicted MW: 56kd
    Observed MW: 56kd
    Primary Ab: 3µg/ml Rabbit Anti-Human GR Antibody
    Second Ab: 0.2µg/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody
    (Catalog: SAA544Rb19)
  • Certificate ISO9001: 2008, ISO13485: 2003 Registered

Specifity

The antibody is a rabbit polyclonal antibody raised against GR. It has been selected for its ability to recognize GR in immunohistochemical staining and western blotting.

Usage

Western blotting: 0.01-3µg/mL;
Immunohistochemistry: 5-20µg/mL;
Optimal working dilutions must be determined by end user.

Storage

Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

Stability

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Giveaways

Citations

  • Doxorubicin Toxicity can be Ameliorated during Antioxidant L-Carnitine SupplementationPubMed: PMC3154045
  • P2×7?Receptor in the Kidneys of Diabetic Rats Submitted to Aerobic Training or to N-Acetylcysteine SupplementationPlos:Source
  • Reduced peripheral blood mtDNA content is associated with impaired glucose‐stimulated islet β cell function in a Chinese population with different degrees of …doi:10.1002
  • Influence of diet on leukocyte telomere length, markers of inflammation and oxidative stress in individuals with varied glucose tolerance: a Chinese population studyPubmed:27071648
  • The Role of PON-1, GR, IL-18, and oxLDL in Depression With and Without Posttraumatic Stress Disorderscience:article
  • The role of PON-1, GR, IL-18, and OxLDL in depression with and without posttraumatic stress disorder.pubmed:28623707
  • Ambroxol attenuates cisplatin-induced hepato and nephrotoxicity via inhibition of p-JNK/p-ERKPubmed: 30383980
  • Negative association between antioxidant vitamin intake and non-alcoholic fatty liver disease in Chinese non-diabetic adults: mediation models involving superoxide …Pubmed: 32985285
  • Triglyceride is independently correlated with insulin resistance and islet beta cell function: a study in population with different glucose and lipid metabolism …Pubmed: 32487177
  • Potential Protective Effect of Dietary Intake of Non-α-Tocopherols on Cellular Aging Markers Mediated by Tumor Necrosis Factor-α in Prediabetes: A Cross …Pubmed: 32509152
  • TNFα Mediates the Interaction of Telomeres and Mitochondria Induced by Hyperglycemia: A Rural Community-Based Cross-Sectional StudyPubmed: 32454945
  • Relationship between Decreased Serum Superoxide Dismutase Activity and Metabolic Syndrome: Synergistic Mediating Role of Insulin Resistance and β …Pubmed: 32617139
  • High Hemoglobin glycation index is associated with telomere attrition independent of HbA1c, mediating by TNFα34562085

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