Polyclonal Antibody to Heparanase (HPSE) Mus musculus (Mouse) Polyclonal antibody

HPA; HPR1; HPSE1; HSE1; Endo-glucoronidase;

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Overview
Properties
  • SourcePolyclonal antibody preparation, Host Rabbit
  • Ig Type IgG, Potency n/a
  • PurificationAntigen-specific affinity chromatography followed by Protein A affinity chromatography
  • LabelNone
  • Immunogen RPA711Mu04-Recombinant Heparanase (HPSE)
  • Buffer FormulationPBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
  • TraitsLiquid, Concentration 0.5mg/ml
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  • Polyclonal Antibody to Heparanase (HPSE) Packages (Simulation)
  • Polyclonal Antibody to Heparanase (HPSE) Packages (Simulation)
  • Polyclonal Antibody to Heparanase (HPSE) DAB staining on IHC-P; Samples: Mouse Ovary Tissue; Primary Ab: 10µg/ml Rabbit Anti-Mouse HPA Antibody Second Ab: 2µg/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody (Catalog: SAA544Rb19)
  • Polyclonal Antibody to Heparanase (HPSE) DAB staining on IHC-P;
    Samples: Mouse Small intestine Tissue;
    Primary Ab: 10µg/ml Rabbit Anti-Mouse HPA Antibody
    Second Ab: 2µg/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody
    (Catalog: SAA544Rb19)
  • Polyclonal Antibody to Heparanase (HPSE) DAB staining on IHC-P;
    Samples: Mouse Colon Tissue;
    Primary Ab: 10µg/ml Rabbit Anti-Mouse HPA Antibody
    Second Ab: 2µg/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody
    (Catalog: SAA544Rb19)
  • Polyclonal Antibody to Heparanase (HPSE) DAB staining on IHC-P;
    Samples: Mouse Cerebrum Tissue;
    Primary Ab: 10µg/ml Rabbit Anti-Mouse HPA Antibody
    Second Ab: 2µg/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody
    (Catalog: SAA544Rb19)
  • Polyclonal Antibody to Heparanase (HPSE) DAB staining on IHC-P;
    Samples: Mouse Heart Tissue;
    Primary Ab: 10µg/ml Rabbit Anti-Mouse HPA Antibody
    Second Ab: 2µg/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody
    (Catalog: SAA544Rb19)
  • Polyclonal Antibody to Heparanase (HPSE) DAB staining on IHC-P;
    Samples: Mouse Testis Tissue;
    Primary Ab: 10µg/ml Rabbit Anti-Mouse HPA Antibody
    Second Ab: 2µg/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody
    (Catalog: SAA544Rb19)
  • PAA711Mu04.jpg Figure. Western Blot; Sample: Recombinant HPA, Mouse.
  • Polyclonal Antibody to Heparanase (HPSE) Western Blot; Sample: Mouse Skin lysate;
    Primary Ab: 2µg/ml Rabbit Anti-Mouse HPA Antibody
    Second Ab: 0.2µg/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody
    (Catalog: SAA544Rb19)
  • Certificate ISO9001: 2008, ISO13485: 2003 Registered

Specifity

The antibody is a rabbit polyclonal antibody raised against HPSE. It has been selected for its ability to recognize HPSE in immunohistochemical staining and western blotting.

Usage

Western blotting: 0.01-2µg/mL
Immunohistochemistry: 5-20µg/mL
Immunocytochemistry: 5-20µg/mL
Optimal working dilutions must be determined by end user.

Storage

Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

Stability

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Organism Species More: Rattus norvegicus (Rat)

Giveaways

Citations

  • PG545, a Heparan Sulfate Mimetic, Reduces Heparanase Expression In Vivo, Blocks Spontaneous Metastases and Enhances Overall Survival in the 4T1 Breast Carcinoma ModelPlosone: Source
  • Assessment of heparanase and heparin-binding growth and angiogenesis factors in the uterine cavity ? uid in women with impaired reproductionNowinylekarskie:Source
  • Unfractionated heparin attenuates intestinal injury in mouse model of sepsis by inhibiting heparanasePubMed: 26191183
  • PI-88 inhibits postoperative recurrence of hepatocellular carcinoma via disrupting the surge of heparanase after liver resectionPubMed: 26415733
  • Assessment of heparanase and heparin-binding growth and angiogenesis factors in the uterine cavity fluid in women with impaired reproductionarticle:84
  • Plasma heparanase is associated with blood glucose levels but not urinary microalbumin excretion in type 2 diabetic nephropathy at the early stage pubmed:28994624

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