Monoclonal Antibody to Myeloperoxidase (MPO) Rattus norvegicus (Rat) Monoclonal antibody

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Overview
Properties
  • SourceMonoclonal antibody preparation, Host Mouse
  • Ig Isotype IgG, Clone Number n/a
  • PurificationAntigen-specific affinity chromatography followed by Protein A affinity chromatography
  • LabelNone
  • Immunogen n/a
  • Buffer FormulationPBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
  • TraitsLiquid, Concentration 1mg/mL
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  • Monoclonal Antibody to Myeloperoxidase (MPO) Packages (Simulation)
  • Monoclonal Antibody to Myeloperoxidase (MPO) Packages (Simulation)
  • Certificate ISO9001: 2008, ISO13485: 2003 Registered

Specifity

The antibody is a mouse monoclonal antibody raised against MPO. It has been selected for its ability to recognize MPO in immunohistochemical staining and western blotting.

Usage

Western blotting: 0.2-2µg/mL;1:500-5000
Immunohistochemistry: 5-20µg/mL;1:50-200
Immunocytochemistry: 5-20µg/mL;1:50-200
Optimal working dilutions must be determined by end user.

Storage

Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

Stability

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Giveaways

Citations

  • Ozone Therapy and Hyperbaric Oxygen Treatment in Lung Injury in Septic RatsPubMed: 21234269
  • Protective Effect of Nicotine on Lipopolysaccharide-Induced Acute Lung Injury in MiceKarger: 000319151
  • Preventive Effects of Valnemulin on Lipopolysaccharide-Induced Acute Lung Injury in MiceSpringerLink: 741437t67767777x
  • A New Immunosensor for Serum Myeloperoxidase Based on Self-Assembly of Multi-Walled Carbon Nanotubes/Thionine/Gold Nanoparticles-ChitosanScientific:1207
  • T cells that target carcinoembryonic antigen eradicate orthotopic pancreatic carcinomas without inducing autoimmune colitis in micePubMed: 22750462
  • Rosuvastatin Reloading before Cardiac Surgery with Cardiopulmonary BypassPubMed: 23406839
  • Protective effects of Ankaferd blood stopper on aspirin-induced oxidative mucosal damage in a rat model of gastric injury.PubMed: 23114375
  • Protective effect of pravastatin on lipopolysaccharide-induced acute lung injury during neutropenia recovery in micePubmed: 23368428
  • Amentoflavone inhibits iNOS, COX-2 expression and modulates cytokine profile, NF-κB signal transduction pathways in rats with ulcerative colitisPubmed: 24126114
  • Neuroprotective effects of α-ketoglutarate and ethyl pyruvate against motor dysfunction and oxidative changes caused by repeated 1-methyl-4-phenyl-1,2,3,6 tetrahydropyridine exposure in micePubmed: 23821591
  • Protective effect of marine mangrove Rhizophora apiculata on acetic acid induced experimental colitis by regulating anti-oxidant enzymes, inflammatory mediators and nuclear factor-kappa B subunitsScienceDirect: S1567576913004153
  • Novel CoQ10 Antidiabetic Mechanisms Underlie Its Positive Effect: Modulation of Insulin and Adiponectine Receptors, Tyrosine Kinase, PI3K, Glucose Transporters, sRAGE and Visfatin in Insulin Resistant/Diabetic RatsPubmed:24586567
  • Heparin-binding protein (HBP/CAP37) - a link to endothelin-1 in endotoxemia-induced pulmonary oedema?Pubmed:24611481
  • Protective Effect of?Acacia ferruginea?against Ulcerative Colitis via Modulating Inflammatory Mediators, Cytokine Profile and NF-κB Signal Transduction PathwaysPubmed:24941292
  • Neuroprotective effects of rosuvastatin against traumatic spinal cord injury in ratsPubmed:25084223
  • Comparison of the Effects of Enoxaparin and Heparin on Inflammatory Biomarkers in Patients with ST-segment Elevated Myocardial Infarction: A prospective Open Label Pilot Clinical TrialPubmed:25237354
  • Gastroprotective effect of nymphayol isolated from Nymphaea stellata (Willd.) flowers: Contribution of antioxidant, anti-inflammatory and anti-apoptotic activitiesPubmed:25289771
  • Melatonin attenuates intestinal ischemia–reperfusion-induced lung injury in rats by upregulating N-myc downstream-regulated gene 2Pubmed:25491174
  • Sulfiredoxin-1 protects primary cultured astrocytes from ischemia-induced damagePubmed:25620665
  • Modulating effect of Biophytum sensitivum extract on rats with acetic acid-induced ulcerative colitisPubmed:5243883
  • The Syk Inhibitor Fostamatinib Decreases the Severity of Colonic Mucosal Damage in a Rodent Model of ColitisPubMed: 26116555
  • Preparation of Monoclonal Antibodies and a Simple Myeloperoxidase-Immunosorbent Assay for Detecting Human MyeloperoxidasePubmed:26978734
  • The efficacy of tyrosine kinase inhibitor dasatinib on colonic mucosal damage in murine model of colitisPubmed:26823039
  • THE ANTI-HYPERCHOLESTEROLEMIC EFFECT OF ULVAN POLYSACCHARIDE EXTRACTED FROM THE GREEN ALGA ULVAFASCIATA ON AGED HYPERCHOLESTEROLEMIC RATSjournals:10835
  • Toll-like receptor 5 signaling restrains T-cell/natural killer T-cell activation and protects against concanavalin A-induced hepatic injury.pubmed:28273362
  • Exploring the Potential of cfDNA Measurements After an Exhaustive Cycle Ergometer Test as a Marker for Performance Related Parameterspubmed:27617485
  • Ellagic Acid Protects Against LPS-Induced Acute Lung Injury Through Inhibition of Nuclear Factor Kappa B, Proinflammatory Cytokines and Enhancement of Interleukin-10c30adb97b06eb4f27063208df7acb7311368.pdf
  • Transplantation of a bacterial consortium ameliorates trinitrobenzenesulfonic acid-induced colitisand intestinal dysbiosis in rats.pubmed:27415182
  • Sevoflurane Attenuates Ischemia-Reperfusion Injury in a Rat Lung Transplantation Model.pubmed:28190546
  • Fluctuation in the number, type and activity of blood neutrophils in cows exhibiting successful and unsuccessful completion of gestation cycle09291016.2017.1311984
  • Effect of Indole-3-carbinol and/or Metformin on Female Patients with Ulcerative Colitis (Premalignant Condition): Role of Oxidative Stress, Apoptosis and Proinflammatory Cytokinesjcrt:5
  • Identification of Tengfu Jiangya Tablet Target Biomarkersjournals:ecam
  • Hyperoxidized albumin modulates neutrophils to induce oxidative stress and inflammation in severe alcoholic hepatitis.pubmed:27775820
  • Enzyme catalysis-electrophoresis titration for multiplex enzymatic assay via moving reactionboundary chip.pubmed:27464600
  • Effect of Poly-herbal mixture and butyric acid feeding on immune parameters of postpartum Murrah buffaloespublication:299575009
  • Frequency of Cholesterol Crystals in Culprit Coronary Artery Aspirate During Acute Myocardial Infarction and Their Relation to Inflammation and Myocardial Injurypubmed:28867129
  • Identification of Tengfu Jiangya Tablet Target Biomarkers with Quantitative Proteomic Techniquepubmed:28408942
  • Effect of photobiomodulation therapy on reducingthe chemo-induced oral mucositis severity and on salivary levels of CXCL8/interleuki8, nitrite, and myeloperoxidase in patients undergoing hematopoietic stem cell transplantation: a randomized clinical trialarticle:10.1007
  • Plasma proteins as potential targets of abnormal Savda syndrome in asthma patients treated with unique Uighur prescriptionpubmed:28672924
  • Upregulation of Intestinal Barrier Function in Mice with DSS-Induced Colitis by a Defined Bacterial Consortium Is Associated with Expansion of IL-17A Producing Gamma Delta T Cells10.3389:fimmu.2017.00824
  • Does penile tourniquet application alter bacterial adhesion to rat urethral cells: an in vitro studypubmed:28693848
  • Ellagic acid protects against LPS-induced acute lung injury through inhibition of nuclear factor kappa B, proinflammatory cytokines and enhancement of interleukin-10 10.1080/09540105.2017.1339670
  • Expression and Role of the Calcium-Sensing Receptor in Rat Peripheral Blood Polymorphonuclear Neutrophilspubmed:29081886
  • Serum Myeloperoxidase in Stable Coronary Artery Disease10.1166/asl.2017.8512
  • Hepatoprotective effect of taurine and coenzyme Q10 and their combination against acrylamide-induced oxidative stress in rats10.4314/tjpr.v16i8.14
  • Role of NOD2 and S100A8/S100A9 in the pathogenesis of Coxsackievirus B3-induced myocarditis10.14279/depositonce-5934
  • Effects of Sulphasalazine in Cerebral Ischemia Reperfusion Injury in Rat.pubmed:28923326
  • The Plasma Kallikrein–Kininogen Pathway is critical in the Pathogenesis of colitis in MicePubmed:29467753
  • Traditional Herbal Medicine-Derived Sulforaphene LFS-01 Reverses Colitis in Mice by Selectively Altering the Gut Microbiota and Promoting Intestinal …Pubmed:29375374
  • Evaluation of the anti-hypertensive effect of Tengfu Jiangya tablet by combination of UPLC-Q-exactive-MS-based metabolomics and iTRAQ-based proteomics …Pubmed:29453042
  • Resolvin D1 promotes corneal epithelial wound healing and restoration of mechanical sensation in diabetic micePubmed:29643724
  • Effect of tropical thermal stress on peri-implantation immune responses in cowsPubmed:29625402
  • Hydrogen‑rich solution against myocardial injury and aquaporin expression via the PI3K/Akt signaling pathway during cardiopulmonary bypass in ratsPubmed:29956781
  • Hydrogen‑rich solution attenuates myocardial injury caused by cardiopulmonary bypass in rats via the Janus‑activated kinase 2/signal transducer and activator of …Pubmed:29928398
  • Associations of periparturient plasma biochemical parameters, endometrial leukocyte esterase and myeloperoxidase, and bacterial detection with clinical and …Pubmed:29332864
  • Sitagliptin attenuates intestinal ischemia/reperfusion injury via cAMP/PKA, PI3K/Akt pathway in a glucagon-like peptide 1 receptor-dependent mannerPubmed: 30195035
  • Effect of β-glucan on acetic acid-induced colitis in rats
  • Chlorogenic Acid Attenuates Dextran Sodium Sulfate-Induced Ulcerative Colitis in Mice through MAPK/ERK/JNK Pathway
  • Bacillus licheniformis Zhengchangsheng® attenuates DSS-induced colitis and modulates the gut microbiota in mice
  • Do Late Phase Hyperbaric and Normobaric Oxygen Therapies have Effect on Liver Damage?: An Experimental Sepsis Model
  • Posttreatment With LYRM03 Protects Rats From Acute Lung Inflammation Induced by Lipopolysaccharide via Suppressing the NF-κB/MyD88/TLR4 AxisPubmed: 31255931
  • Efficacy assessment of co-treated alpha-ketoglutarate and N-acetyl cysteine against the subchronic toxicity of cyanide in ratsPubmed: 31244408
  • The effects of hydrogen-rich saline solution on intestinal anastomosis performed after intestinal ischemia reperfusion injury
  • Annexin A1 mimetic peptide Ac2-26 attenuates mechanical injury induced corneal scarring and inflammationPubmed: 31519322
  • SHP2 deficiency promotes Staphylococcus aureus pneumonia following influenza infectionPubmed: 31782850
  • Effects of ozone preconditioning on recovery of rat colon anastomosis after preoperative radiotherapyPubmed: 31895975
  • Effects of a high concentration of hydrogen on neurological function after traumatic brain injury in diabetic ratsPubmed: 31926128
  • Native myeloperoxidase is required to make the experimental vasculitis modelPubmed: 31864385
  • Rational Modulation of the Luminescence of Upconversion Nanomaterials with Phycocyanin for the Sensing and Imaging of Myeloperoxidase during an Inflammatory …Pubmed: 32126753
  • Peripartum changes in the activity and expression of neutrophils may predispose to the postpartum occurrence of metritis in dairy cowsPubmed: 33229058
  • The HDL from septic-ARDS patients with composition changes exacerbates pulmonary endothelial dysfunction and acute lung injury induced by cecal ligation …Pubmed: 33148285
  • Lead exposure induces cell autophagy via blocking the Akt/mTOR signaling in rat astrocytesPubmed: 32879255
  • A comparative study on various immunological parameters influencing embryo survivability in crossbred dairy cowsPubmed: 32810791
  • Sensitive and rapid lateral-flow assay for early detection of subclinical mammary infection in dairy cowsPubmed: 32636462
  • Gambogic acid alleviates inflammation and apoptosis and protects the blood-milk barrier in mastitis induced by LPSPubmed: 32585608
  • Protective Effects of SIRT6 Overexpression against DSS-Induced Colitis in MicePubmed: 32580272
  • DNA microarray analysis of hypothermia-exposed murine lungs for identification of forensic biomarkersPubmed: 33161360
  • Juglanin administration protects skin against UVB‑induced injury by reducing Nrf2‑dependent ROS generationPubmed: 32377697
  • The adverse alterations of HDL in quality promote septic ARDS via exacerbated pulmonary endothelial dysfunction
  • Ameliorating Effects of ¦Â-glucan on Epigastric Artery Island Flap Ischemia-Reperfusion Injury33477077
  • Dental pulp stem cells overexpressing hepatocyte growth factor facilitate the repair of DSS-induced ulcerative colitis33413675
  • Inhibition of nitric oxide synthase aggravates brain injury in diabetic rats with traumatic brain injury33433486
  • Strictosamide alleviates the inflammation in an acute ulcerative colitis (UC) model33595775
  • Protective effects of hydrogen rich saline solution on ventral penile Mathieu type flap with penile tourniquet application in rats33608226
  • JAK3 and PI3K mediates the suppressive effects of interferon tau on neutrophil extracellular traps formation during peri-implantation period33862433
  • Macrophage Extracellular Traps Aggravate Iron Overload©\Related Liver Ischemia/Reperfusion Injury33959955
  • Characterization of a Rat Model of Myeloperoxidase-Anti-Neutrophil Cytoplasmic Antibody-Associated Crescentic Glomerulonephritis33910203
  • Topical calcitriol application promotes diabetic corneal wound healing and reinnervation through inhibiting NLRP3 inflammasome activation34144035
  • Daphnetin ameliorates acute lung injury in mice with severe acute pancreatitis by inhibiting the JAK2¨CSTAT3 pathway34075160
  • ¦Ê?opioid receptor agonist U50488H attenuates postoperative cognitive dysfunction of cardiopulmonary bypass rats through the PI3K/AKT/Nrf2/HO?1 pathway33649775
  • Novel 1, 3, 4-Oxadiazole Derivatives of Pyrrolo [3, 4-d] Pyridazinone Exert Anti-Inflammatory Activity without Acute Gastrotoxicity in the Carrageenan-Induced …34754217
  • Calycosin attenuates severe acute pancreatitis-associated acute lung injury by curtailing high mobility group box 1-induced inflammation34908806
  • Blocking tumor necrosis factor-α delays progression of chronic obstructive pulmonary disease in rats through inhibiting MAPK signaling pathway and activating …34630665
  • Hyperactive neutrophils infiltrate vital organs of tumor bearing host and contribute to gradual systemic deterioration with tumor progression34890699
  • Saccharomyces cerevisiae fermentation products reduce bacterial endotoxin concentrations and inflammation during grain-based subacute ruminal acidosis …Pubmed:34998547
  • Plasma Concentrations of New Biochemical Markers of Atherosclerosis in Patients with Dyslipidemia—A Pilot StudyPubmed:35743980
  • Serum Myeloperoxidase as A Biomarker of Asthma Severity Among Adults: A Case Control StudyPubmed:35765520
  • Bovine lactoferricin ameliorates intestinal inflammation and mucosal barrier lesions in colitis through NF-κB/NLRP3 signaling pathways
  • A Novel Role of Tinospora Cordifolia in Amelioration of Cancer-Induced Systemic Deterioration By Taming Neutrophil Infiltration and Hyperactivation

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