17-Beta-Hydroxysteroid Dehydrogenase Type 8 (HSD17b8)
RING2; FABG; FABGL; H2-KE6; HKE6; KE6; SDR30C1; Estradiol 17-Beta-Dehydrogenase 8; Short Chain Dehydrogenase/Reductase Family 30C,Member 1
HKE6 possesses remarkable amino acid sequence conservation with several bacterial proteins having oxidoreductase activity. HKE6 also shows significant homology with the 2 unique functional domains containing the nucleotide cofactor-binding site and the consensus motif characteristic of the members of the superfamily of short-chain alcohol dehydrogenases such as human and rat steroid and prostaglandin dehydrogenases. mouse Ke6 is a 17-beta-hydroxysteroid dehydrogenase and can regulate the concentration of biologically active estrogens and androgens. The Ke6 enzyme is preferentially an oxidative enzyme and inactivates estradiol, testosterone, and dihydrotestosterone. However, the enzyme has some reductive activity and can synthesize estradiol from estrone.
Organism species: Homo sapiens (Human)
- Customized Service n/a Recombinant 17-Beta-Hydroxysteroid Dehydrogenase Type 8 (HSD17b8) Recombinant Protein Customized Service Offer
- Customized Service n/a Monoclonal Antibody to 17-Beta-Hydroxysteroid Dehydrogenase Type 8 (HSD17b8) Monoclonal Antibody Customized Service Offer
- Customized Service n/a Polyclonal Antibody to 17-Beta-Hydroxysteroid Dehydrogenase Type 8 (HSD17b8) Polyclonal Antibody Customized Service Offer
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Organism species: Mus musculus (Mouse)
- Customized Service n/a Recombinant 17-Beta-Hydroxysteroid Dehydrogenase Type 8 (HSD17b8) Recombinant Protein Customized Service Offer
- Customized Service n/a Monoclonal Antibody to 17-Beta-Hydroxysteroid Dehydrogenase Type 8 (HSD17b8) Monoclonal Antibody Customized Service Offer
- Customized Service n/a Polyclonal Antibody to 17-Beta-Hydroxysteroid Dehydrogenase Type 8 (HSD17b8) Polyclonal Antibody Customized Service Offer
- Customized Service n/a CLIA Kit for 17-Beta-Hydroxysteroid Dehydrogenase Type 8 (HSD17b8) CLIA Kit Customized Service Offer
- Customized Service n/a ELISA Kit for 17-Beta-Hydroxysteroid Dehydrogenase Type 8 (HSD17b8) ELISA Kit Customized Service Offer
Organism species: Rattus norvegicus (Rat)
- Customized Service n/a Recombinant 17-Beta-Hydroxysteroid Dehydrogenase Type 8 (HSD17b8) Recombinant Protein Customized Service Offer
- Customized Service n/a Monoclonal Antibody to 17-Beta-Hydroxysteroid Dehydrogenase Type 8 (HSD17b8) Monoclonal Antibody Customized Service Offer
- Customized Service n/a Polyclonal Antibody to 17-Beta-Hydroxysteroid Dehydrogenase Type 8 (HSD17b8) Polyclonal Antibody Customized Service Offer
- Customized Service n/a CLIA Kit for 17-Beta-Hydroxysteroid Dehydrogenase Type 8 (HSD17b8) CLIA Kit Customized Service Offer
- Customized Service n/a ELISA Kit for 17-Beta-Hydroxysteroid Dehydrogenase Type 8 (HSD17b8) ELISA Kit Customized Service Offer