5-Methyltetrahydrofolate Homocysteine Methyltransferase (MTR)

CblG; MS; MeSe; MetH Methionine Synthase; Vitamin-B12 dependent methionine synthase
5-Methyltetrahydrofolate Homocysteine Methyltransferase (MTR)
The remethylation of homocysteine to form methionine is catalyzed by the cytoplasmic enzyme 5-methyltetrahydrofolate-homocysteine S-methyltransferase (EC 2.1.1.13), which is also called methionine synthase. This enzyme requires methylcobalamin (MeCbl), a derivative of cobalamin, or vitamin B12, for activity.The patient was a 6-month-old girl with mental retardation, megaloblastic anemia, and high folate activity in the serum and red cells.
For this reason and also because rodent and human forms of the enzyme were electrophoretically distinguishable, these workers could use binding to identify the presence of human methyltransferase (MTR) in rodent-human somatic cell hybrids. By this approach, they assigned the methyltransferase gene to chromosome 1.
Organism species: Homo sapiens (Human)
Organism species: Mus musculus (Mouse)
  • Protein RPG462Mu01Recombinant 5-Methyltetrahydrofolate Homocysteine Methyltransferase (MTR)Customize
  • AntibodyPAG462Mu01Polyclonal Antibody to 5-Methyltetrahydrofolate Homocysteine Methyltransferase (MTR)Customize
  • AntibodyMAG462Mu21Monoclonal Antibody to 5-Methyltetrahydrofolate Homocysteine Methyltransferase (MTR)Customize
  • Assay KitSEG462MuELISA Kit for 5-Methyltetrahydrofolate Homocysteine Methyltransferase (MTR)Customize
  • Assay KitSCG462MuCLIA Kit for 5-Methyltetrahydrofolate Homocysteine Methyltransferase (MTR)Customize
Organism species: Rattus norvegicus (Rat)
  • Protein RPG462Ra01Recombinant 5-Methyltetrahydrofolate Homocysteine Methyltransferase (MTR)Customize
  • AntibodyPAG462Ra01Polyclonal Antibody to 5-Methyltetrahydrofolate Homocysteine Methyltransferase (MTR)Customize
  • AntibodyMAG462Ra21Monoclonal Antibody to 5-Methyltetrahydrofolate Homocysteine Methyltransferase (MTR)Customize
  • Assay KitSEG462RaELISA Kit for 5-Methyltetrahydrofolate Homocysteine Methyltransferase (MTR)Customize
  • Assay KitSCG462RaCLIA Kit for 5-Methyltetrahydrofolate Homocysteine Methyltransferase (MTR)Customize
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