5',3'-Nucleotidase, Cytosolic (NT5C)
DNT; DNT1; P5N2; PN-I; PN-II; UMPH2; cdN; 5'Nucleotidase,Deoxy(Pyrimidine)Cytosolic Type C; Uridine 5-Prime Monophosphate Hydrolase 2; 5'(3')-deoxyribonucleotidase, cytosolic
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Pyrimidine 5-prime nucleotidase (P5N; EC 3.1.3.5), also called uridine 5-prime monophosphate hydrolase (UMPH), catalyzes the dephosphorylation of the pyrimidine 5-prime monophosphates UMP and CMP to the corresponding nucleosides. There are 2 isozymes of pyrimidine 5-prime nucleotidase in red blood cells, referred to as type I (UMPH1) and type II (UMPH2). Detected in skeletal muscle, heart and pancreas.
Dephosphorylates the 5' and 2'(3')-phosphates of deoxyribonucleotides, with a preference for dUMP and dTMP, intermediate activity towards dGMP, and low activity towards dCMP and dAMP
Organism species: Homo sapiens (Human)
- Recombinant protein RPD938Hu01 Recombinant 5',3'-Nucleotidase, Cytosolic (NT5C) In Stock
- Polyclonal antibody PAD938Hu01 Polyclonal Antibody to 5',3'-Nucleotidase, Cytosolic (NT5C) In Stock
- Sandwich ELISA SED938Hu ELISA Kit for 5',3'-Nucleotidase, Cytosolic (NT5C) In Stock
Organism species: Mus musculus (Mouse)
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- Polyclonal antibody PAD938Mu01 Polyclonal Antibody to 5',3'-Nucleotidase, Cytosolic (NT5C) In Stock
- Sandwich ELISA SED938Mu ELISA Kit for 5',3'-Nucleotidase, Cytosolic (NT5C) In Stock
Organism species: Rattus norvegicus (Rat)
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- Sandwich ELISA SED938Ra ELISA Kit for 5',3'-Nucleotidase, Cytosolic (NT5C) In Stock