6-Pyruvoyltetrahydropterin Synthase (PTS)

PTPS
6-Pyruvoyltetrahydropterin Synthase (PTS)
The PTS gene encodes 6-pyruvoyl-tetrahydropterin synthase (EC 4.6.1.10), an enzyme involved in the biosynthesis of tetrahydrobiopterin (BH4), an essential cofactor for aromatic amino acid hydroxylases, such as hepatic phenylalanine hydroxylase (PAH), tyrosine hydroxylase (TH), and tryptophan hydroxylase (TPH1), as well as for all 3 forms of nitric oxide synthase. The deduced 145-residue protein has a molecular mass of 16.4 kD. The human amino acid sequence showed 82% identity with the rat liver sequence. Expression of the cDNA in E. coli yielded the active enzyme and showed immunoreactivity with antibodies against the rat liver PTS.PTS gene spans about 8 kb and contains 6 exons, as revealed by DNA sequence analysis.
Organism species: Homo sapiens (Human)
  • Protein RPH278Hu01Recombinant 6-Pyruvoyltetrahydropterin Synthase (PTS)Customize
  • AntibodyPAH278Hu01Polyclonal Antibody to 6-Pyruvoyltetrahydropterin Synthase (PTS)Customize
  • AntibodyMAH278Hu21Monoclonal Antibody to 6-Pyruvoyltetrahydropterin Synthase (PTS)Customize
  • Assay KitSEH278HuELISA Kit for 6-Pyruvoyltetrahydropterin Synthase (PTS)Customize
  • Assay KitSCH278HuCLIA Kit for 6-Pyruvoyltetrahydropterin Synthase (PTS)Customize
Organism species: Mus musculus (Mouse)
  • Protein RPH278Mu01Recombinant 6-Pyruvoyltetrahydropterin Synthase (PTS)Customize
  • AntibodyPAH278Mu01Polyclonal Antibody to 6-Pyruvoyltetrahydropterin Synthase (PTS)Customize
  • AntibodyMAH278Mu21Monoclonal Antibody to 6-Pyruvoyltetrahydropterin Synthase (PTS)Customize
  • Assay KitSEH278MuELISA Kit for 6-Pyruvoyltetrahydropterin Synthase (PTS)Customize
  • Assay KitSCH278MuCLIA Kit for 6-Pyruvoyltetrahydropterin Synthase (PTS)Customize
Organism species: Rattus norvegicus (Rat)
  • Protein RPH278Ra01Recombinant 6-Pyruvoyltetrahydropterin Synthase (PTS)Customize
  • AntibodyPAH278Ra01Polyclonal Antibody to 6-Pyruvoyltetrahydropterin Synthase (PTS)Customize
  • AntibodyMAH278Ra21Monoclonal Antibody to 6-Pyruvoyltetrahydropterin Synthase (PTS)Customize
  • Assay KitSEH278RaELISA Kit for 6-Pyruvoyltetrahydropterin Synthase (PTS)Customize
  • Assay KitSCH278RaCLIA Kit for 6-Pyruvoyltetrahydropterin Synthase (PTS)Customize
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