ADP Ribosylation Factor Interacting Protein 1 (ARFIP1)
Arfaptin-1
Sequence analysis predicted that the 341-amino acid arfaptin-1 protein, which is 60% identical to arfaptin-2, contains a leucine zipper motif, which is interrupted with a met at position 157, and several potential phosphorylation sites.
In vitro binding analysis showed that arfaptin-1 binds to nonmyristoylated GTP-bound ARF3, but not to GDP-bound ARF3, and also to ARF1, another class I ARF. It binds with lower affinity to ARF5, a class II ARF, and with very little affinity to ARF6 , a class III ARF. Immunoblot analysis indicated that arfaptin-1 is recruited from the cytosol to Golgi membranes by ARFs in a guanosine 5-prime-O-(3-thiotriphosphate)-dependent and brefeldin A-sensitive manner but is not a constituent of coatomer .
Organism species: Homo sapiens (Human)
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Organism species: Mus musculus (Mouse)
- Customized Service n/a Recombinant ADP Ribosylation Factor Interacting Protein 1 (ARFIP1) Recombinant Protein Customized Service Offer
- Customized Service n/a Monoclonal Antibody to ADP Ribosylation Factor Interacting Protein 1 (ARFIP1) Monoclonal Antibody Customized Service Offer
- Customized Service n/a Polyclonal Antibody to ADP Ribosylation Factor Interacting Protein 1 (ARFIP1) Polyclonal Antibody Customized Service Offer
- Customized Service n/a CLIA Kit for ADP Ribosylation Factor Interacting Protein 1 (ARFIP1) CLIA Kit Customized Service Offer
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Organism species: Rattus norvegicus (Rat)
- Customized Service n/a Recombinant ADP Ribosylation Factor Interacting Protein 1 (ARFIP1) Recombinant Protein Customized Service Offer
- Customized Service n/a Monoclonal Antibody to ADP Ribosylation Factor Interacting Protein 1 (ARFIP1) Monoclonal Antibody Customized Service Offer
- Customized Service n/a Polyclonal Antibody to ADP Ribosylation Factor Interacting Protein 1 (ARFIP1) Polyclonal Antibody Customized Service Offer
- Customized Service n/a CLIA Kit for ADP Ribosylation Factor Interacting Protein 1 (ARFIP1) CLIA Kit Customized Service Offer
- Customized Service n/a ELISA Kit for ADP Ribosylation Factor Interacting Protein 1 (ARFIP1) ELISA Kit Customized Service Offer