ADP Ribosylation Like Factor 6 Interacting Protein 5 (ARL6IP5)
DERP11; GTRAP3-18; HSPC127; JWA; PRAF3; Addicsin; hp22; Jmx; Cytoskeleton-related vitamin A-responsive protein; Dermal papilla-derived protein 11; Prenylated Rab acceptor 2
ARL6IP5 may be associated with the cytoskeleton. A similar protein in rats may play a role in the regulation of cell differentiation. The rat protein binds and inhibits the cell membrane glutamate transporter EAAC1. The expression of the rat gene is upregulated by retinoic acid, which results in a specific reduction in EAAC1-mediated glutamate transport.Like EAAC1, GTRAP3-18 is expressed in numerous tissues. It localizes to the cell membrane and cytoplasm, and specifically interacts with the carboxy-terminal intracellular domain of EAAC1. Increasing the expression of GTRAP3-18 in cells reduces EAAC1-mediated glutamate transport by lowering substrate affinity. The expression of GTRAP3-18 can be upregulated by retinoic acid, which results in a specific reduction of EAAC1-mediated glutamate transport.
Organism species: Homo sapiens (Human)
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Organism species: Mus musculus (Mouse)
- Customized Service n/a Recombinant ADP Ribosylation Like Factor 6 Interacting Protein 5 (ARL6IP5) Recombinant Protein Customized Service Offer
- Customized Service n/a Monoclonal Antibody to ADP Ribosylation Like Factor 6 Interacting Protein 5 (ARL6IP5) Monoclonal Antibody Customized Service Offer
- Customized Service n/a Polyclonal Antibody to ADP Ribosylation Like Factor 6 Interacting Protein 5 (ARL6IP5) Polyclonal Antibody Customized Service Offer
- Customized Service n/a CLIA Kit for ADP Ribosylation Like Factor 6 Interacting Protein 5 (ARL6IP5) CLIA Kit Customized Service Offer
- Customized Service n/a ELISA Kit for ADP Ribosylation Like Factor 6 Interacting Protein 5 (ARL6IP5) ELISA Kit Customized Service Offer
Organism species: Rattus norvegicus (Rat)
- Customized Service n/a Recombinant ADP Ribosylation Like Factor 6 Interacting Protein 5 (ARL6IP5) Recombinant Protein Customized Service Offer
- Customized Service n/a Monoclonal Antibody to ADP Ribosylation Like Factor 6 Interacting Protein 5 (ARL6IP5) Monoclonal Antibody Customized Service Offer
- Customized Service n/a Polyclonal Antibody to ADP Ribosylation Like Factor 6 Interacting Protein 5 (ARL6IP5) Polyclonal Antibody Customized Service Offer
- Customized Service n/a CLIA Kit for ADP Ribosylation Like Factor 6 Interacting Protein 5 (ARL6IP5) CLIA Kit Customized Service Offer
- Customized Service n/a ELISA Kit for ADP Ribosylation Like Factor 6 Interacting Protein 5 (ARL6IP5) ELISA Kit Customized Service Offer