AF4/FMR2 Family, Member 3 (AFF3)
LAF4; MLLT2-Like; Lymphoid Nuclear Protein Related To AF4
AFF3 encodes a tissue-restricted nuclear transcriptional activator that is preferentially expressed in lymphoid tissue. Isolation of this protein initially defined a highly conserved LAF4/MLLT2 gene family of nuclear transcription factors that may function in lymphoid development and oncogenesis. In some ALL patients, this gene has been found fused to the gene for MLL. Multiple alternatively spliced transcript variants that encode different proteins have been found for this gene.The deduced 1,227-amino acid protein has a molecular mass of 135 kD in B-cell lines. The protein, which the authors designated LAF4 (lymphoid nuclear protein related to AF4), showed high sequence similarity, particularly in the N-terminal and C-terminal regions, with AF4 (MLTT2), the gene that is fused to the MLL gene in t(4;11)(q21;q23).
Organism species: Homo sapiens (Human)
- Customized Service n/a Recombinant AF4/FMR2 Family, Member 3 (AFF3) Recombinant Protein Customized Service Offer
- Customized Service n/a Monoclonal Antibody to AF4/FMR2 Family, Member 3 (AFF3) Monoclonal Antibody Customized Service Offer
- Customized Service n/a Polyclonal Antibody to AF4/FMR2 Family, Member 3 (AFF3) Polyclonal Antibody Customized Service Offer
- Customized Service n/a CLIA Kit for AF4/FMR2 Family, Member 3 (AFF3) CLIA Kit Customized Service Offer
- Customized Service n/a ELISA Kit for AF4/FMR2 Family, Member 3 (AFF3) ELISA Kit Customized Service Offer
Organism species: Mus musculus (Mouse)
- Customized Service n/a Recombinant AF4/FMR2 Family, Member 3 (AFF3) Recombinant Protein Customized Service Offer
- Customized Service n/a Monoclonal Antibody to AF4/FMR2 Family, Member 3 (AFF3) Monoclonal Antibody Customized Service Offer
- Customized Service n/a Polyclonal Antibody to AF4/FMR2 Family, Member 3 (AFF3) Polyclonal Antibody Customized Service Offer
- Customized Service n/a CLIA Kit for AF4/FMR2 Family, Member 3 (AFF3) CLIA Kit Customized Service Offer
- Customized Service n/a ELISA Kit for AF4/FMR2 Family, Member 3 (AFF3) ELISA Kit Customized Service Offer
Organism species: Rattus norvegicus (Rat)
- Customized Service n/a Recombinant AF4/FMR2 Family, Member 3 (AFF3) Recombinant Protein Customized Service Offer
- Customized Service n/a Monoclonal Antibody to AF4/FMR2 Family, Member 3 (AFF3) Monoclonal Antibody Customized Service Offer
- Customized Service n/a Polyclonal Antibody to AF4/FMR2 Family, Member 3 (AFF3) Polyclonal Antibody Customized Service Offer
- Customized Service n/a CLIA Kit for AF4/FMR2 Family, Member 3 (AFF3) CLIA Kit Customized Service Offer
- Customized Service n/a ELISA Kit for AF4/FMR2 Family, Member 3 (AFF3) ELISA Kit Customized Service Offer