ATP Binding Cassette Transporter B11 (ABCB11)

ABC-B11; BSEP; PFIC2; ABC16; SPGP; PGY4; Progressive Familial Intrahepatic Cholestasis 2; Bile salt export pump
ATP Binding Cassette Transporter B11 (ABCB11)
ABCB11 is an ABC transporter named BSEP (Bile Salt Export Pump), or sPgp (sister of P-glycoprotein). This membrane-associated protein is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White).This protein is a member of the MDR/TAP subfamily. Some members of the MDR/TAP subfamily are involved in multidrug resistance. This particular protein is responsible for the transport of taurocholate and other cholate conjugates from hepatocytes (liver cells) to the bile. In humans, the activity of this transporter is the major determinant of bile formation and bile flow.
Organism species: Homo sapiens (Human)
  • Protein RPD641Hu01Recombinant ATP Binding Cassette Transporter B11 (ABCB11)Customize
  • AntibodyPAD641Hu01Polyclonal Antibody to ATP Binding Cassette Transporter B11 (ABCB11)Customize
  • AntibodyMAD641Hu21Monoclonal Antibody to ATP Binding Cassette Transporter B11 (ABCB11)Customize
  • Assay KitSED641HuELISA Kit for ATP Binding Cassette Transporter B11 (ABCB11)Customize
  • Assay KitSCD641HuCLIA Kit for ATP Binding Cassette Transporter B11 (ABCB11)Customize
Organism species: Mus musculus (Mouse)
Organism species: Rattus norvegicus (Rat)
  • Protein RPD641Ra01Recombinant ATP Binding Cassette Transporter B11 (ABCB11)Customize
  • AntibodyPAD641Ra01Polyclonal Antibody to ATP Binding Cassette Transporter B11 (ABCB11)Customize
  • AntibodyMAD641Ra21Monoclonal Antibody to ATP Binding Cassette Transporter B11 (ABCB11)Customize
  • Assay KitSED641RaELISA Kit for ATP Binding Cassette Transporter B11 (ABCB11)Customize
  • Assay KitSCD641RaCLIA Kit for ATP Binding Cassette Transporter B11 (ABCB11)Customize
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