ATP Binding Cassette Transporter B11 (ABCB11)
ABC-B11; BSEP; PFIC2; ABC16; SPGP; PGY4; Progressive Familial Intrahepatic Cholestasis 2; Bile salt export pump
ABCB11 is an ABC transporter named BSEP (Bile Salt Export Pump), or sPgp (sister of P-glycoprotein). This membrane-associated protein is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White).This protein is a member of the MDR/TAP subfamily. Some members of the MDR/TAP subfamily are involved in multidrug resistance. This particular protein is responsible for the transport of taurocholate and other cholate conjugates from hepatocytes (liver cells) to the bile. In humans, the activity of this transporter is the major determinant of bile formation and bile flow.
Organism species: Homo sapiens (Human)
- Recombinant protein RPD641Hu01 Recombinant ATP Binding Cassette Transporter B11 (ABCB11) In Stock
- Polyclonal antibody PAD641Hu01 Polyclonal Antibody to ATP Binding Cassette Transporter B11 (ABCB11) In Stock
- Customized Service n/a CLIA Kit for ATP Binding Cassette Transporter B11 (ABCB11) CLIA Kit Customized Service Offer
- Customized Service n/a ELISA Kit for ATP Binding Cassette Transporter B11 (ABCB11) ELISA Kit Customized Service Offer
Organism species: Mus musculus (Mouse)
- Recombinant protein RPD641Mu01 Recombinant ATP Binding Cassette Transporter B11 (ABCB11) In Stock
- Polyclonal antibody PAD641Mu01 Polyclonal Antibody to ATP Binding Cassette Transporter B11 (ABCB11) In Stock
- Customized Service n/a CLIA Kit for ATP Binding Cassette Transporter B11 (ABCB11) CLIA Kit Customized Service Offer
- Customized Service n/a ELISA Kit for ATP Binding Cassette Transporter B11 (ABCB11) ELISA Kit Customized Service Offer
Organism species: Rattus norvegicus (Rat)
- Customized Service n/a Recombinant ATP Binding Cassette Transporter B11 (ABCB11) Recombinant Protein Customized Service Offer
- Customized Service n/a Monoclonal Antibody to ATP Binding Cassette Transporter B11 (ABCB11) Monoclonal Antibody Customized Service Offer
- Customized Service n/a Polyclonal Antibody to ATP Binding Cassette Transporter B11 (ABCB11) Polyclonal Antibody Customized Service Offer
- Customized Service n/a CLIA Kit for ATP Binding Cassette Transporter B11 (ABCB11) CLIA Kit Customized Service Offer
- Customized Service n/a ELISA Kit for ATP Binding Cassette Transporter B11 (ABCB11) ELISA Kit Customized Service Offer