ATP Binding Cassette Transporter C8 (ABCC8)

ABC-C8; PHHI; MRP8; ABC36; HHF1; HI; HRINS; SUR; SUR1; TNDM2; Sulfonylurea Receptor(Hyperinsulinemia)
ATP Binding Cassette Transporter C8 (ABCC8)
ABCC8 is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. This protein functions as a modulator of ATP-sensitive potassium channels and insulin release. Mutations and deficiencies in this protein have been observed in patients with hyperinsulinemic hypoglycemia of infancy, an autosomal recessive disorder of unregulated and high insulin secretion. Mutations have also been associated with non-insulin-dependent diabetes mellitus type II, an autosomal dominant disease of defective insulin secretion.
Organism species: Homo sapiens (Human)
Organism species: Mus musculus (Mouse)
  • Protein RPD628Mu01Recombinant ATP Binding Cassette Transporter C8 (ABCC8)Customize
  • AntibodyPAD628Mu01Polyclonal Antibody to ATP Binding Cassette Transporter C8 (ABCC8)Customize
  • AntibodyMAD628Mu21Monoclonal Antibody to ATP Binding Cassette Transporter C8 (ABCC8)Customize
  • Assay KitSED628MuELISA Kit for ATP Binding Cassette Transporter C8 (ABCC8)Customize
  • Assay KitSCD628MuCLIA Kit for ATP Binding Cassette Transporter C8 (ABCC8)Customize
Organism species: Rattus norvegicus (Rat)
  • Protein RPD628Ra01Recombinant ATP Binding Cassette Transporter C8 (ABCC8)Customize
  • AntibodyPAD628Ra01Polyclonal Antibody to ATP Binding Cassette Transporter C8 (ABCC8)Customize
  • AntibodyMAD628Ra21Monoclonal Antibody to ATP Binding Cassette Transporter C8 (ABCC8)Customize
  • Assay KitSED628RaELISA Kit for ATP Binding Cassette Transporter C8 (ABCC8)Customize
  • Assay KitSCD628RaCLIA Kit for ATP Binding Cassette Transporter C8 (ABCC8)Customize
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