Axis Inhibition Protein (AXIN)
AXIN1
Axin-1 encodes a cytoplasmic protein which contains a regulation of G-protein signaling (RGS) domain and a dishevelled and axin (DIX) domain. The encoded protein interacts with adenomatosis polyposis coli, catenin (cadherin-associated protein), beta 1, 88kDa, glycogen synthase kinase 3 beta, protein phosphate 2, and itself. This protein functions as a negative regulator of the wingless-type MMTV integration site family, member 1 (WNT) signaling pathway and can induce apoptosis. The crystal structure of a portion of this protein, alone and in a complex with other proteins, has been resolved. Mutations in this gene have been associated with hepatocellular carcinoma, hepatoblastomas, ovarian endometriod adenocarcinomas, and medullablastomas.
Organism species: Homo sapiens (Human)
- Recombinant protein RPC191Hu01 Recombinant Axis Inhibition Protein (AXIN) In Stock
- Polyclonal antibody PAC191Hu01 Polyclonal Antibody to Axis Inhibition Protein (AXIN) In Stock
- Sandwich ELISA SEC191Hu ELISA Kit for Axis Inhibition Protein (AXIN) In Stock
Organism species: Mus musculus (Mouse)
- Recombinant protein RPC191Mu01 Recombinant Axis Inhibition Protein (AXIN) In Stock
- Recombinant protein RPC191Mu02 Recombinant Axis Inhibition Protein (AXIN) In Stock
- Polyclonal antibody PAC191Mu01 Polyclonal Antibody to Axis Inhibition Protein (AXIN) In Stock
- Polyclonal antibody PAC191Mu02 Polyclonal Antibody to Axis Inhibition Protein (AXIN) In Stock
- Customized Service n/a CLIA Kit for Axis Inhibition Protein (AXIN) CLIA Kit Customized Service Offer
- Customized Service n/a ELISA Kit for Axis Inhibition Protein (AXIN) ELISA Kit Customized Service Offer
Organism species: Rattus norvegicus (Rat)
- Recombinant protein RPC191Ra01 Recombinant Axis Inhibition Protein (AXIN) In Stock
- Polyclonal antibody PAC191Ra01 Polyclonal Antibody to Axis Inhibition Protein (AXIN) In Stock
- Customized Service n/a CLIA Kit for Axis Inhibition Protein (AXIN) CLIA Kit Customized Service Offer
- Customized Service n/a ELISA Kit for Axis Inhibition Protein (AXIN) ELISA Kit Customized Service Offer