Actin Related Protein 10 (ACTR10)
ARP10; HARP11; ACTR11; Arp11
The dynein activator dynactin is a multiprotein complex with distinct microtubule- and cargo-binding domains. The cargo-binding domain contains a short, actin-like filament of the actin-related protein Arp1, a second actin-related protein, Arp11, and conventional actin. Arp11 is present in a protein complex localized at the pointed end of the Arp1 minifilament, whereas actin capping protein (CapZ) is present at the barbed end. Either might cooperate with conventional actin to cap Arp1. Like Arp1, cytosolic Arp11 is found only in dynactin, suggesting that Arp11 and free cytosolic actin do not interact significantly. Recombinant Arp11 and Arp1 were demonstrated to interact by coprecipitation. Arp11 significantly decreases the formation of these organized Arp1 assemblies. Finally, this assay was used to confirm the identity of a putative Arp11 homolog in Drosophila melanogaster.
Organism species: Homo sapiens (Human)
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Organism species: Mus musculus (Mouse)
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- Customized Service n/a Monoclonal Antibody to Actin Related Protein 10 (ACTR10) Monoclonal Antibody Customized Service Offer
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Organism species: Rattus norvegicus (Rat)
- Customized Service n/a Recombinant Actin Related Protein 10 (ACTR10) Recombinant Protein Customized Service Offer
- Customized Service n/a Monoclonal Antibody to Actin Related Protein 10 (ACTR10) Monoclonal Antibody Customized Service Offer
- Customized Service n/a Polyclonal Antibody to Actin Related Protein 10 (ACTR10) Polyclonal Antibody Customized Service Offer
- Customized Service n/a CLIA Kit for Actin Related Protein 10 (ACTR10) CLIA Kit Customized Service Offer
- Customized Service n/a ELISA Kit for Actin Related Protein 10 (ACTR10) ELISA Kit Customized Service Offer