Adaptor Related Protein Complex 2 Alpha 2 (AP2a2)
ADTAB; CLAPA2; HIP9; HYPJ; Alpha-Adaptin C; Huntingtin Interacting Protein J; Clathrin-Associated/Assembly/Adaptor Protein,Large,Alpha 2; 100 kDa coated vesicle protein C
By randomly sequencing cDNA clones from size-fractionated human brain cDNA libraries, Nagase et al. (1998) identified AP2A2, which they designated KIAA0899. The deduced 929-amino acid protein shares more than 97% sequence identity with rat alpha-adaptin. By RT-PCR analysis followed by ELISA for quantitation, they detected ubiquitous, low-to-moderate expression of KIAA0899, with highest levels in spinal cord and fetal and adult brain and lowest levels in spleen.
Using the N terminus of huntingtin (HTT) in a yeast 2-hybrid screen of a testis cDNA library, Faber et al. (1998) identified AP2A2, which they designated huntingtin yeast partner J (HYPJ). The predicted protein shares significant sequence identity with mouse alpha-adaptin C.
Organism species: Homo sapiens (Human)
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Organism species: Mus musculus (Mouse)
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Organism species: Rattus norvegicus (Rat)
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- Customized Service n/a Polyclonal Antibody to Adaptor Related Protein Complex 2 Alpha 2 (AP2a2) Polyclonal Antibody Customized Service Offer
- Customized Service n/a CLIA Kit for Adaptor Related Protein Complex 2 Alpha 2 (AP2a2) CLIA Kit Customized Service Offer
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