Adaptor Related Protein Complex 4 Epsilon 1 (AP4e1)
Epsilon-adaptin; AP-4 adaptor complex subunit epsilon
The heterotetrameric adaptor protein (AP) complexes sort integral membrane proteins at various stages of the endocytic and secretory pathways.
AP4E1 shows an apparent molecular mass of about 140 kD and is part of a 280-kD complex containing AP4B1, AP4S1, and AP4M1. By immunoprecipitation and reprecipitation of HeLa cell lysates, they confirmed interaction between AP4B1 and AP4E1. Immunolocalization of the AP4B1 subunit in HeLa cells revealed that the AP4 complex associates with the trans-Golgi network or an adjacent structure. The association was sensitive to brefeldin-A treatment, indicating that the membrane localization of AP4 is dependent upon the small GTP-binding protein ARF1.
Organism species: Homo sapiens (Human)
- Customized Service n/a Recombinant Adaptor Related Protein Complex 4 Epsilon 1 (AP4e1) Recombinant Protein Customized Service Offer
- Customized Service n/a Monoclonal Antibody to Adaptor Related Protein Complex 4 Epsilon 1 (AP4e1) Monoclonal Antibody Customized Service Offer
- Customized Service n/a Polyclonal Antibody to Adaptor Related Protein Complex 4 Epsilon 1 (AP4e1) Polyclonal Antibody Customized Service Offer
- Customized Service n/a CLIA Kit for Adaptor Related Protein Complex 4 Epsilon 1 (AP4e1) CLIA Kit Customized Service Offer
- Customized Service n/a ELISA Kit for Adaptor Related Protein Complex 4 Epsilon 1 (AP4e1) ELISA Kit Customized Service Offer
Organism species: Mus musculus (Mouse)
- Customized Service n/a Recombinant Adaptor Related Protein Complex 4 Epsilon 1 (AP4e1) Recombinant Protein Customized Service Offer
- Customized Service n/a Monoclonal Antibody to Adaptor Related Protein Complex 4 Epsilon 1 (AP4e1) Monoclonal Antibody Customized Service Offer
- Customized Service n/a Polyclonal Antibody to Adaptor Related Protein Complex 4 Epsilon 1 (AP4e1) Polyclonal Antibody Customized Service Offer
- Customized Service n/a CLIA Kit for Adaptor Related Protein Complex 4 Epsilon 1 (AP4e1) CLIA Kit Customized Service Offer
- Customized Service n/a ELISA Kit for Adaptor Related Protein Complex 4 Epsilon 1 (AP4e1) ELISA Kit Customized Service Offer
Organism species: Rattus norvegicus (Rat)
- Customized Service n/a Recombinant Adaptor Related Protein Complex 4 Epsilon 1 (AP4e1) Recombinant Protein Customized Service Offer
- Customized Service n/a Monoclonal Antibody to Adaptor Related Protein Complex 4 Epsilon 1 (AP4e1) Monoclonal Antibody Customized Service Offer
- Customized Service n/a Polyclonal Antibody to Adaptor Related Protein Complex 4 Epsilon 1 (AP4e1) Polyclonal Antibody Customized Service Offer
- Customized Service n/a CLIA Kit for Adaptor Related Protein Complex 4 Epsilon 1 (AP4e1) CLIA Kit Customized Service Offer
- Customized Service n/a ELISA Kit for Adaptor Related Protein Complex 4 Epsilon 1 (AP4e1) ELISA Kit Customized Service Offer