Adenylosuccinate Lyase (ADSL)

AMPS; ASase; Adenylosuccinase
Adenylosuccinate Lyase (ADSL)
Adenylsuccinate lyase is involved in both de novo synthesis of purines and formation of adenosine monophosphate from inosine monophosphate. It catalyzes two reactions in AMP biosynthesis: the removal of a fumarate from succinylaminoimidazole carboxamide (SAICA) ribotide to give aminoimidazole carboxamide ribotide (AICA) and removal of fumarate from adenylosuccinate to give AMP.
Adenylosuccinase deficiency results in succinylpurinemic autism, psychomotor retardation, and , in some cases, growth retardation associated with muscle wasting and epilepsy. Two transcript variants encoding different isoforms have been found for this gene. Ubiquitously expressed. Both isoforms are produced by all tissues.
 
Organism species: Homo sapiens (Human)
  • Protein RPG452Hu01Recombinant Adenylosuccinate Lyase (ADSL)Customize
  • AntibodyPAG452Hu01Polyclonal Antibody to Adenylosuccinate Lyase (ADSL)Customize
  • AntibodyMAG452Hu21Monoclonal Antibody to Adenylosuccinate Lyase (ADSL)Customize
  • Assay KitSEG452HuELISA Kit for Adenylosuccinate Lyase (ADSL)Customize
  • Assay KitSCG452HuCLIA Kit for Adenylosuccinate Lyase (ADSL)Customize
Organism species: Mus musculus (Mouse)
  • Protein RPG452Mu01Recombinant Adenylosuccinate Lyase (ADSL)Customize
  • AntibodyPAG452Mu01Polyclonal Antibody to Adenylosuccinate Lyase (ADSL)Customize
  • AntibodyMAG452Mu21Monoclonal Antibody to Adenylosuccinate Lyase (ADSL)Customize
  • Assay KitSEG452MuELISA Kit for Adenylosuccinate Lyase (ADSL)Customize
  • Assay KitSCG452MuCLIA Kit for Adenylosuccinate Lyase (ADSL)Customize
Organism species: Rattus norvegicus (Rat)
  • Protein RPG452Ra01Recombinant Adenylosuccinate Lyase (ADSL)Customize
  • AntibodyPAG452Ra01Polyclonal Antibody to Adenylosuccinate Lyase (ADSL)Customize
  • AntibodyMAG452Ra21Monoclonal Antibody to Adenylosuccinate Lyase (ADSL)Customize
  • Assay KitSEG452RaELISA Kit for Adenylosuccinate Lyase (ADSL)Customize
  • Assay KitSCG452RaCLIA Kit for Adenylosuccinate Lyase (ADSL)Customize
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