Amyloid Beta Precursor Protein Binding Protein A1 (APBA1)
APB-A1; MINT1; X11; X11A; X11ALPHA; Adapter protein X11alpha; Neuron-specific X11 protein; Neuronal Munc18-1-interacting protein 1
APBA1 is a member of the X11 protein family. It is a neuronal adaptor protein that interacts with the Alzheimer's disease amyloid precursor protein (APP). It stabilises APP and inhibits production of proteolytic APP fragments including the A beta peptide that is deposited in the brains of Alzheimer's disease patients. This gene product is believed to be involved in signal transduction processes. It is also regarded as a putative vesicular trafficking protein in the brain that can form a complex with the potential to couple synaptic vesicle exocytosis to neuronal cell adhesion. The deduced 837-amino acid MINT1 protein contains an N-terminal domain that binds to Munc18-1, a middle phosphotyrosine-binding (PTB) domain that binds to phosphatidylinositol phosphates, and 2 C-terminal PDZ domains.
Organism species: Homo sapiens (Human)
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Organism species: Mus musculus (Mouse)
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Organism species: Rattus norvegicus (Rat)
- Customized Service n/a Recombinant Amyloid Beta Precursor Protein Binding Protein A1 (APBA1) Recombinant Protein Customized Service Offer
- Customized Service n/a Monoclonal Antibody to Amyloid Beta Precursor Protein Binding Protein A1 (APBA1) Monoclonal Antibody Customized Service Offer
- Customized Service n/a Polyclonal Antibody to Amyloid Beta Precursor Protein Binding Protein A1 (APBA1) Polyclonal Antibody Customized Service Offer
- Customized Service n/a CLIA Kit for Amyloid Beta Precursor Protein Binding Protein A1 (APBA1) CLIA Kit Customized Service Offer
- Customized Service n/a ELISA Kit for Amyloid Beta Precursor Protein Binding Protein A1 (APBA1) ELISA Kit Customized Service Offer