Ankyrin Repeat And SOCS Box Containing Protein 6 (ASB6)
ASB6 belongs to a family of ankyrin repeat proteins that, along with four other protein families, contain a C-terminal SOCS box motif. Growing evidence suggests that the SOCS box, similar to the F-box, acts as a bridge between specific substrate-binding domains and the more generic proteins that comprise a large family of E3 ubiquitin protein ligases.
The SOCS box domain mediates the interaction with the Elongin BC complex, an adapter module in different E3 ubiquitin-protein ligase complexes. Probable substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.
Organism species: Homo sapiens (Human)
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Organism species: Mus musculus (Mouse)
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Organism species: Rattus norvegicus (Rat)
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- Customized Service n/a Polyclonal Antibody to Ankyrin Repeat And SOCS Box Containing Protein 6 (ASB6) Polyclonal Antibody Customized Service Offer
- Customized Service n/a CLIA Kit for Ankyrin Repeat And SOCS Box Containing Protein 6 (ASB6) CLIA Kit Customized Service Offer
- Customized Service n/a ELISA Kit for Ankyrin Repeat And SOCS Box Containing Protein 6 (ASB6) ELISA Kit Customized Service Offer