Ankyrin Repeat And SOCS Box Containing Protein 14 (ASB14)
ASB14 is a member of the ankyrin repeat and SOCS box-containing (ASB) family of proteins. They contain ankyrin repeat sequence and a SOCS box domain. The SOCS box serves to couple suppressor of cytokine signalling (SOCS) proteins and their binding partners with the elongin B and C complex, possibly targeting them for degradation. Alternative splicing results in multiple transcript variants encoding different isoforms.
Growing evidence suggests that the SOCS box, similar to the F-box, acts as a bridge between specific substrate-binding domains and the more generic proteins that comprise a large family of E3 ubiquitin protein ligases. In this way, SOCS proteins regulate protein turnover by targeting proteins for polyubiquitination and, therefore, for proteasome-mediated degradation.
Organism species: Homo sapiens (Human)
- Customized Service n/a Recombinant Ankyrin Repeat And SOCS Box Containing Protein 14 (ASB14) Recombinant Protein Customized Service Offer
- Customized Service n/a Monoclonal Antibody to Ankyrin Repeat And SOCS Box Containing Protein 14 (ASB14) Monoclonal Antibody Customized Service Offer
- Customized Service n/a Polyclonal Antibody to Ankyrin Repeat And SOCS Box Containing Protein 14 (ASB14) Polyclonal Antibody Customized Service Offer
- Customized Service n/a CLIA Kit for Ankyrin Repeat And SOCS Box Containing Protein 14 (ASB14) CLIA Kit Customized Service Offer
- Customized Service n/a ELISA Kit for Ankyrin Repeat And SOCS Box Containing Protein 14 (ASB14) ELISA Kit Customized Service Offer
Organism species: Mus musculus (Mouse)
- Customized Service n/a Recombinant Ankyrin Repeat And SOCS Box Containing Protein 14 (ASB14) Recombinant Protein Customized Service Offer
- Customized Service n/a Monoclonal Antibody to Ankyrin Repeat And SOCS Box Containing Protein 14 (ASB14) Monoclonal Antibody Customized Service Offer
- Customized Service n/a Polyclonal Antibody to Ankyrin Repeat And SOCS Box Containing Protein 14 (ASB14) Polyclonal Antibody Customized Service Offer
- Customized Service n/a CLIA Kit for Ankyrin Repeat And SOCS Box Containing Protein 14 (ASB14) CLIA Kit Customized Service Offer
- Customized Service n/a ELISA Kit for Ankyrin Repeat And SOCS Box Containing Protein 14 (ASB14) ELISA Kit Customized Service Offer
Organism species: Rattus norvegicus (Rat)
- Customized Service n/a Recombinant Ankyrin Repeat And SOCS Box Containing Protein 14 (ASB14) Recombinant Protein Customized Service Offer
- Customized Service n/a Monoclonal Antibody to Ankyrin Repeat And SOCS Box Containing Protein 14 (ASB14) Monoclonal Antibody Customized Service Offer
- Customized Service n/a Polyclonal Antibody to Ankyrin Repeat And SOCS Box Containing Protein 14 (ASB14) Polyclonal Antibody Customized Service Offer
- Customized Service n/a CLIA Kit for Ankyrin Repeat And SOCS Box Containing Protein 14 (ASB14) CLIA Kit Customized Service Offer
- Customized Service n/a ELISA Kit for Ankyrin Repeat And SOCS Box Containing Protein 14 (ASB14) ELISA Kit Customized Service Offer