Anterior Pharynx Defective 1B (APH1B)
PSFL; APH-1B; Gamma-secretase subunit APH-1B; Presenilin-stabilization factor-like
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APH1 is a multipass transmembrane protein that interacts with presenilin and nicastrin (APH2) as a functional component of the gamma-secretase complex. The gamma-secretase complex is required for the intramembrane proteolysis of a number of membrane proteins, including the amyloid-beta precursor protein and Notch.
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APH1B encodes a multi-pass transmembrane protein that is a functional component of the gamma-secretase complex, which also contains presenilin and nicastrin. This protein represents a stabilizing cofactor for the presenilin holoprotein in the complex. The gamma-secretase complex catalyzes the cleavage of integral proteins such as notch receptors and beta-amyloid precursor protein.
Organism species: Homo sapiens (Human)
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Organism species: Mus musculus (Mouse)
- Customized Service n/a Recombinant Anterior Pharynx Defective 1B (APH1B) Recombinant Protein Customized Service Offer
- Customized Service n/a Monoclonal Antibody to Anterior Pharynx Defective 1B (APH1B) Monoclonal Antibody Customized Service Offer
- Customized Service n/a Polyclonal Antibody to Anterior Pharynx Defective 1B (APH1B) Polyclonal Antibody Customized Service Offer
- Customized Service n/a CLIA Kit for Anterior Pharynx Defective 1B (APH1B) CLIA Kit Customized Service Offer
- Customized Service n/a ELISA Kit for Anterior Pharynx Defective 1B (APH1B) ELISA Kit Customized Service Offer
Organism species: Rattus norvegicus (Rat)
- Customized Service n/a Recombinant Anterior Pharynx Defective 1B (APH1B) Recombinant Protein Customized Service Offer
- Customized Service n/a Monoclonal Antibody to Anterior Pharynx Defective 1B (APH1B) Monoclonal Antibody Customized Service Offer
- Customized Service n/a Polyclonal Antibody to Anterior Pharynx Defective 1B (APH1B) Polyclonal Antibody Customized Service Offer
- Customized Service n/a CLIA Kit for Anterior Pharynx Defective 1B (APH1B) CLIA Kit Customized Service Offer
- Customized Service n/a ELISA Kit for Anterior Pharynx Defective 1B (APH1B) ELISA Kit Customized Service Offer