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ITEM PROTEIN ANTIBODY ASSAY KIT CELL
Ataxin 3 (ATXN3)
AT3; ATX3; JOS; MJD; MJD1; SCA3; Machado-Joseph disease; Spinocerebellar Ataxia 3;Olivopontocerebellar Ataxia 3; Autosomal dominant,Ataxin 3
Machado-Joseph disease, also known as spinocerebellar ataxia-3, is an autosomal dominant neurologic disorder. The protein encoded by the ATXN3 gene contains (CAG)n repeats in the coding region, and the expansion of these repeats from the normal 13-36 to 68-79 is the cause of Machado-Joseph disease. There is an inverse correlation between the age of onset and CAG repeat numbers. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
ATXN3 has deubiquitinase activity and appears to be a component of the ubiquitin proteasome system. It may also have roles in transcriptional regulation and neuroprotection.
Organism species: Homo sapiens (Human)
CATALOG NO. PRODUCT NAME
Proteins RPD250Hu01 Recombinant Ataxin 3 (ATXN3) Customize
Antibodies PAD250Hu01 Polyclonal Antibody to Ataxin 3 (ATXN3) Customize
MAD250Hu21 Monoclonal Antibody to Ataxin 3 (ATXN3) Customize
Assay Kits SED250Hu ELISA Kit for Ataxin 3 (ATXN3) Customize
SCD250Hu CLIA Kit for Ataxin 3 (ATXN3) Customize
Organism species: Mus musculus (Mouse)
CATALOG NO. PRODUCT NAME
Proteins RPD250Mu01 Recombinant Ataxin 3 (ATXN3) Customize
Antibodies PAD250Mu01 Polyclonal Antibody to Ataxin 3 (ATXN3) Customize
MAD250Mu21 Monoclonal Antibody to Ataxin 3 (ATXN3) Customize
Assay Kits SED250Mu ELISA Kit for Ataxin 3 (ATXN3) Customize
SCD250Mu CLIA Kit for Ataxin 3 (ATXN3) Customize
Organism species: Rattus norvegicus (Rat)
CATALOG NO. PRODUCT NAME
Proteins RPD250Ra01 Recombinant Ataxin 3 (ATXN3) Customize
Antibodies PAD250Ra01 Polyclonal Antibody to Ataxin 3 (ATXN3) Customize
MAD250Ra21 Monoclonal Antibody to Ataxin 3 (ATXN3) Customize
Assay Kits SED250Ra ELISA Kit for Ataxin 3 (ATXN3) Customize
SCD250Ra CLIA Kit for Ataxin 3 (ATXN3) Customize