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ITEM PROTEIN ANTIBODY ASSAY KIT CELL
Ataxin 7 (ATXN7)
SCA7; OPCA3; ADCAII; Spinocerebellar Ataxia 7; Olivopontocerebellar Atrophy With Retinal Degeneration
ADCAII, which always presents with retinal degeneration (SCA7), and ADCAIII often referred to as the `pure' cerebellar syndrome (SCA5), are most likely homogeneous disorders. Several SCA genes have been cloned and shown to contain CAG repeats in their coding regions. ADCA is caused by the expansion of the CAG repeats, producing an elongated polyglutamine tract in the corresponding protein.
The expanded repeats are variable in size and unstable, usually increasing in size when transmitted to successive generations. This locus has been mapped to chromosome 3, and it has been determined that the diseased allele associated with Spinocerebellar ataxia-7, contains 38-130 CAG repeats (near the N-terminus), compared to 7-17 in the normal allele.
Organism species: Homo sapiens (Human)
CATALOG NO. PRODUCT NAME
Proteins RPD249Hu01 Recombinant Ataxin 7 (ATXN7) Customize
Antibodies PAD249Hu01 Polyclonal Antibody to Ataxin 7 (ATXN7) Customize
MAD249Hu21 Monoclonal Antibody to Ataxin 7 (ATXN7) Customize
Assay Kits SED249Hu ELISA Kit for Ataxin 7 (ATXN7) Customize
SCD249Hu CLIA Kit for Ataxin 7 (ATXN7) Customize
Organism species: Mus musculus (Mouse)
CATALOG NO. PRODUCT NAME
Proteins RPD249Mu01 Recombinant Ataxin 7 (ATXN7) Customize
Antibodies PAD249Mu01 Polyclonal Antibody to Ataxin 7 (ATXN7) Customize
MAD249Mu21 Monoclonal Antibody to Ataxin 7 (ATXN7) Customize
Assay Kits SED249Mu ELISA Kit for Ataxin 7 (ATXN7) Customize
SCD249Mu CLIA Kit for Ataxin 7 (ATXN7) Customize
Organism species: Rattus norvegicus (Rat)
CATALOG NO. PRODUCT NAME
Proteins RPD249Ra01 Recombinant Ataxin 7 (ATXN7) Customize
Antibodies PAD249Ra01 Polyclonal Antibody to Ataxin 7 (ATXN7) Customize
MAD249Ra21 Monoclonal Antibody to Ataxin 7 (ATXN7) Customize
Assay Kits SED249Ra ELISA Kit for Ataxin 7 (ATXN7) Customize
SCD249Ra CLIA Kit for Ataxin 7 (ATXN7) Customize