Ataxin 7 (ATXN7)

SCA7; OPCA3; ADCAII; Spinocerebellar Ataxia 7; Olivopontocerebellar Atrophy With Retinal Degeneration
Ataxin 7 (ATXN7)
ADCAII, which always presents with retinal degeneration (SCA7), and ADCAIII often referred to as the `pure' cerebellar syndrome (SCA5), are most likely homogeneous disorders. Several SCA genes have been cloned and shown to contain CAG repeats in their coding regions. ADCA is caused by the expansion of the CAG repeats, producing an elongated polyglutamine tract in the corresponding protein. The expanded repeats are variable in size and unstable, usually increasing in size when transmitted to successive generations. This locus has been mapped to chromosome 3, and it has been determined that the diseased allele associated with Spinocerebellar ataxia-7, contains 38-130 CAG repeats (near the N-terminus), compared to 7-17 in the normal allele.
Organism species: Homo sapiens (Human)
  • Protein RPD249Hu01Recombinant Ataxin 7 (ATXN7)Customize
  • AntibodyPAD249Hu01Polyclonal Antibody to Ataxin 7 (ATXN7)Customize
  • AntibodyMAD249Hu21Monoclonal Antibody to Ataxin 7 (ATXN7)Customize
  • Assay KitSED249HuELISA Kit for Ataxin 7 (ATXN7)Customize
  • Assay KitSCD249HuCLIA Kit for Ataxin 7 (ATXN7)Customize
Organism species: Mus musculus (Mouse)
  • Protein RPD249Mu01Recombinant Ataxin 7 (ATXN7)Customize
  • AntibodyPAD249Mu01Polyclonal Antibody to Ataxin 7 (ATXN7)Customize
  • AntibodyMAD249Mu21Monoclonal Antibody to Ataxin 7 (ATXN7)Customize
  • Assay KitSED249MuELISA Kit for Ataxin 7 (ATXN7)Customize
  • Assay KitSCD249MuCLIA Kit for Ataxin 7 (ATXN7)Customize
Organism species: Rattus norvegicus (Rat)
  • Protein RPD249Ra01Recombinant Ataxin 7 (ATXN7)Customize
  • AntibodyPAD249Ra01Polyclonal Antibody to Ataxin 7 (ATXN7)Customize
  • AntibodyMAD249Ra21Monoclonal Antibody to Ataxin 7 (ATXN7)Customize
  • Assay KitSED249RaELISA Kit for Ataxin 7 (ATXN7)Customize
  • Assay KitSCD249RaCLIA Kit for Ataxin 7 (ATXN7)Customize
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