B-Cell Scaffold Protein With Ankyrin Repeats Protein 1 (BANK1)
BANK1 is a B-cell-specific scaffold protein that functions in B-cell receptor-induced calcium mobilization from intracellular stores. This protein can also promote Lyn-mediated tyrosine phosphorylation of inositol 1,4,5-trisphosphate receptors. Polymorphisms in this gene are associated with susceptibility to systemic lupus erythematosus. Alternative splicing results in multiple transcript variants.
The deduced 755-amino acid protein has a calculated molecular mass of 85.5 kD. BANK1 shares amino acid homology with mouse Bcap (PIK3AP1) especially over the ankyrin repeat motifs and predicted coiled-coil regions. BANK1 contains 23 tyrosine residues that may be phosphorylated including several potential SH2 domain binding sites.
Organism species: Homo sapiens (Human)
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Organism species: Mus musculus (Mouse)
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- Customized Service n/a Monoclonal Antibody to B-Cell Scaffold Protein With Ankyrin Repeats Protein 1 (BANK1) Monoclonal Antibody Customized Service Offer
- Customized Service n/a Polyclonal Antibody to B-Cell Scaffold Protein With Ankyrin Repeats Protein 1 (BANK1) Polyclonal Antibody Customized Service Offer
- Customized Service n/a CLIA Kit for B-Cell Scaffold Protein With Ankyrin Repeats Protein 1 (BANK1) CLIA Kit Customized Service Offer
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Organism species: Rattus norvegicus (Rat)
- Customized Service n/a Recombinant B-Cell Scaffold Protein With Ankyrin Repeats Protein 1 (BANK1) Recombinant Protein Customized Service Offer
- Customized Service n/a Monoclonal Antibody to B-Cell Scaffold Protein With Ankyrin Repeats Protein 1 (BANK1) Monoclonal Antibody Customized Service Offer
- Customized Service n/a Polyclonal Antibody to B-Cell Scaffold Protein With Ankyrin Repeats Protein 1 (BANK1) Polyclonal Antibody Customized Service Offer
- Customized Service n/a CLIA Kit for B-Cell Scaffold Protein With Ankyrin Repeats Protein 1 (BANK1) CLIA Kit Customized Service Offer
- Customized Service n/a ELISA Kit for B-Cell Scaffold Protein With Ankyrin Repeats Protein 1 (BANK1) ELISA Kit Customized Service Offer