Bcl10 Associated Gene Protein (BAG)
C1orf52; Chromosome 1 Open Reading Frame 52
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BCL10 Associated Gene Protein (BAG) Expressed in all tissues tested including heart, placenta, liver, skeletal muscle, kidney and pancreas. Weak expression in brain and lung. BCL10 contains a caspase recruitment domain (CARD), and has been shown to induce apoptosis and to activate NF-kappaB. This protein is reported to interact with other CARD domain containing proteins including CARD9, 10, 11 and 14, which are thought to function as upstream regulators in NF-kappaB signaling. This protein is found to form a complex with MALT1, a protein encoded by another gene known to be translocated in MALT lymphoma. MALT1 and this protein are thought to synergize in the activation of NF-kappaB, and the deregulation of either of them may contribute to the same pathogenetic process that leads to the malignancy.
Organism species: Homo sapiens (Human)
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Organism species: Mus musculus (Mouse)
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Organism species: Rattus norvegicus (Rat)
- Customized Service n/a Recombinant Bcl10 Associated Gene Protein (BAG) Recombinant Protein Customized Service Offer
- Customized Service n/a Monoclonal Antibody to Bcl10 Associated Gene Protein (BAG) Monoclonal Antibody Customized Service Offer
- Customized Service n/a Polyclonal Antibody to Bcl10 Associated Gene Protein (BAG) Polyclonal Antibody Customized Service Offer
- Customized Service n/a CLIA Kit for Bcl10 Associated Gene Protein (BAG) CLIA Kit Customized Service Offer
- Customized Service n/a ELISA Kit for Bcl10 Associated Gene Protein (BAG) ELISA Kit Customized Service Offer