Bcl2 Associated Athanogene 4 (BAG4)
SODD; Silencer Of Death Domains; BAG family molecular chaperone regulator 4
BAG4 encoded by this gene is a member of the BAG1-related protein family. BAG1 is an anti-apoptotic protein that functions through interactions with a variety of cell apoptosis and growth related proteins including BCL-2, Raf-protein kinase, steroid hormone receptors, growth factor receptors and members of the heat shock protein 70 kDa family. This protein contains a BAG domain near the C-terminus, which could bind and inhibit the chaperone activity of Hsc70/Hsp70. This protein was found to be associated with the death domain of tumor necrosis factor receptor type 1 (TNF-R1) and death receptor-3 (DR3), and thereby negatively regulates downstream cell death signaling. The regulatory role of this protein in cell death was demonstrated in epithelial cells which undergo apoptosis while integrin mediated matrix contacts are lost.
Organism species: Homo sapiens (Human)
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- Customized Service n/a Monoclonal Antibody to Bcl2 Associated Athanogene 4 (BAG4) Monoclonal Antibody Customized Service Offer
- Customized Service n/a Polyclonal Antibody to Bcl2 Associated Athanogene 4 (BAG4) Polyclonal Antibody Customized Service Offer
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Organism species: Mus musculus (Mouse)
- Recombinant protein RPF226Mu01 Recombinant Bcl2 Associated Athanogene 4 (BAG4) In Stock
- Polyclonal antibody PAF226Mu01 Polyclonal Antibody to Bcl2 Associated Athanogene 4 (BAG4) In Stock
- Customized Service n/a CLIA Kit for Bcl2 Associated Athanogene 4 (BAG4) CLIA Kit Customized Service Offer
- Customized Service n/a ELISA Kit for Bcl2 Associated Athanogene 4 (BAG4) ELISA Kit Customized Service Offer
Organism species: Rattus norvegicus (Rat)
- Customized Service n/a Recombinant Bcl2 Associated Athanogene 4 (BAG4) Recombinant Protein Customized Service Offer
- Customized Service n/a Monoclonal Antibody to Bcl2 Associated Athanogene 4 (BAG4) Monoclonal Antibody Customized Service Offer
- Customized Service n/a Polyclonal Antibody to Bcl2 Associated Athanogene 4 (BAG4) Polyclonal Antibody Customized Service Offer
- Customized Service n/a CLIA Kit for Bcl2 Associated Athanogene 4 (BAG4) CLIA Kit Customized Service Offer
- Customized Service n/a ELISA Kit for Bcl2 Associated Athanogene 4 (BAG4) ELISA Kit Customized Service Offer