Bcl2 Like Protein 14 (BCL2L14)
BCLG; BCL-G; Apoptosis regulator Bcl-G; Apoptosis facilitator Bcl-2-like protein 14
BCL2L14 belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities.Three alternatively spliced transcript variants encoding two distinct isoforms have been reported for this gene.BCLGS had a more potent activity that was dependent on its BH3 domain. BCLGL with a deleted BH2 domain was as potent as BCLGS, suggesting that the BH2 domain negatively regulates BCLGL proapoptotic activity. Coimmunoprecipitation and yeast 2-hybrid analysis showed that BCLGS interacts with antiapoptotic BCL2 family members, such as BCLXL, through its BH3 domain. Confocal microscopy and cellular fractionation analysis demonstrated that BCLGS colocalizes with mitochondria independently of the BH3 domain.
Organism species: Homo sapiens (Human)
- Customized Service n/a Recombinant Bcl2 Like Protein 14 (BCL2L14) Recombinant Protein Customized Service Offer
- Customized Service n/a Monoclonal Antibody to Bcl2 Like Protein 14 (BCL2L14) Monoclonal Antibody Customized Service Offer
- Customized Service n/a Polyclonal Antibody to Bcl2 Like Protein 14 (BCL2L14) Polyclonal Antibody Customized Service Offer
- Customized Service n/a CLIA Kit for Bcl2 Like Protein 14 (BCL2L14) CLIA Kit Customized Service Offer
- Customized Service n/a ELISA Kit for Bcl2 Like Protein 14 (BCL2L14) ELISA Kit Customized Service Offer
Organism species: Mus musculus (Mouse)
- Customized Service n/a Recombinant Bcl2 Like Protein 14 (BCL2L14) Recombinant Protein Customized Service Offer
- Customized Service n/a Monoclonal Antibody to Bcl2 Like Protein 14 (BCL2L14) Monoclonal Antibody Customized Service Offer
- Customized Service n/a Polyclonal Antibody to Bcl2 Like Protein 14 (BCL2L14) Polyclonal Antibody Customized Service Offer
- Customized Service n/a CLIA Kit for Bcl2 Like Protein 14 (BCL2L14) CLIA Kit Customized Service Offer
- Customized Service n/a ELISA Kit for Bcl2 Like Protein 14 (BCL2L14) ELISA Kit Customized Service Offer
Organism species: Rattus norvegicus (Rat)
- Customized Service n/a Recombinant Bcl2 Like Protein 14 (BCL2L14) Recombinant Protein Customized Service Offer
- Customized Service n/a Monoclonal Antibody to Bcl2 Like Protein 14 (BCL2L14) Monoclonal Antibody Customized Service Offer
- Customized Service n/a Polyclonal Antibody to Bcl2 Like Protein 14 (BCL2L14) Polyclonal Antibody Customized Service Offer
- Customized Service n/a CLIA Kit for Bcl2 Like Protein 14 (BCL2L14) CLIA Kit Customized Service Offer
- Customized Service n/a ELISA Kit for Bcl2 Like Protein 14 (BCL2L14) ELISA Kit Customized Service Offer