BRCA1 Associated ATM Activator 1 (BRAT1)

BAAT1; C7orf27; BRCA1-associated protein required for ATM activation protein 1
BRCA1 Associated ATM Activator 1 (BRAT1)
BRAT1 Contains 2 HEAT repeats. Ubiquitously expressed. Required for activation of ATM following ionizing radiation. May act by regulating dephosphorylation of ATM.The HEAT repeat is a tandemly repeated, 37-47 amino acid long module occurring in a number of cytoplasmic proteins, including the four name-giving proteins huntingtin, elongation factor 3 (EF3), the 65 Kd alpha regulatory subunit of protein phosphatase 2A (PP2A) and the yeast PI3-kinase TOR1. Arrays of HEAT repeats consists of 3 to 36 units forming a rod-like helical structure and appear to function as protein-protein interaction surfaces. It has been noted that many HEAT repeat-containing proteins are involved in intracellular transport processes. In the crystal structure of PP2A PR65/A, the HEAT repeats consist of pairs of antiparallel alpha helices.
Organism species: Homo sapiens (Human)
  • Protein RPU066Hu01Recombinant BRCA1 Associated ATM Activator 1 (BRAT1)Customize
  • AntibodyPAU066Hu01Polyclonal Antibody to BRCA1 Associated ATM Activator 1 (BRAT1)Customize
  • AntibodyMAU066Hu21Monoclonal Antibody to BRCA1 Associated ATM Activator 1 (BRAT1)Customize
  • Assay KitSEU066HuELISA Kit for BRCA1 Associated ATM Activator 1 (BRAT1)Customize
  • Assay KitSCU066HuCLIA Kit for BRCA1 Associated ATM Activator 1 (BRAT1)Customize
Organism species: Mus musculus (Mouse)
  • Protein RPU066Mu01Recombinant BRCA1 Associated ATM Activator 1 (BRAT1)Customize
  • AntibodyPAU066Mu01Polyclonal Antibody to BRCA1 Associated ATM Activator 1 (BRAT1)Customize
  • AntibodyMAU066Mu21Monoclonal Antibody to BRCA1 Associated ATM Activator 1 (BRAT1)Customize
  • Assay KitSEU066MuELISA Kit for BRCA1 Associated ATM Activator 1 (BRAT1)Customize
  • Assay KitSCU066MuCLIA Kit for BRCA1 Associated ATM Activator 1 (BRAT1)Customize
Organism species: Rattus norvegicus (Rat)
  • Protein RPU066Ra01Recombinant BRCA1 Associated ATM Activator 1 (BRAT1)Customize
  • AntibodyPAU066Ra01Polyclonal Antibody to BRCA1 Associated ATM Activator 1 (BRAT1)Customize
  • AntibodyMAU066Ra21Monoclonal Antibody to BRCA1 Associated ATM Activator 1 (BRAT1)Customize
  • Assay KitSEU066RaELISA Kit for BRCA1 Associated ATM Activator 1 (BRAT1)Customize
  • Assay KitSCU066RaCLIA Kit for BRCA1 Associated ATM Activator 1 (BRAT1)Customize
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