Bradykinin Receptor B1 (BDKRB1)
B1BKR; B1R; BKB1R; BKR1; BRADYB1; BDKR-B1
) is a G-protein coupled receptor encoded by the BDKRB1 gene in humans. Its principal ligand is bradykinin, a 9 amino acid peptide generated in pathophysiologic conditions such as inflammation, trauma, burns, shock, and allergy. The B1 receptor is one of two of G protein-coupled receptors that have been found which bind bradykinin and mediate responses to these pathophysiologic conditions.
B1 protein is synthesized de novo following tissue injury and receptor binding leads to an increase in the cytosolic calcium ion concentration, ultimately resulting in chronic and acute inflammatory responses.
Organism species: Homo sapiens (Human)
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Organism species: Mus musculus (Mouse)
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Organism species: Rattus norvegicus (Rat)
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- Customized Service n/a Monoclonal Antibody to Bradykinin Receptor B1 (BDKRB1) Monoclonal Antibody Customized Service Offer
- Customized Service n/a Polyclonal Antibody to Bradykinin Receptor B1 (BDKRB1) Polyclonal Antibody Customized Service Offer
- Customized Service n/a CLIA Kit for Bradykinin Receptor B1 (BDKRB1) CLIA Kit Customized Service Offer
- Customized Service n/a ELISA Kit for Bradykinin Receptor B1 (BDKRB1) ELISA Kit Customized Service Offer