Breakpoint Cluster Region (BCR)
ALL; BCR/FGFR1; BCR1; CML; FGFR1/BCR; PHL; Renal carcinoma antigen NY-REN-26
The BCR gene is one of the two genes in the bcr-abl complex, which is associated with the Philadelphia chromosome.A reciprocal translocation between chromosomes 22 and 9 produces the Philadelphia chromosome, which is often found in patients with chronic myelogenous leukemia. The chromosome 22 breakpoint for this translocation is located within the BCR gene. The translocation produces a fusion protein which is encoded by sequence from both BCR and ABL, the gene at the chromosome 9 breakpoint. Although the BCR-ABL fusion protein has been extensively studied, the function of the normal BCR gene product is not clear. The protein has serine/threonine kinase activity and is a GTPase-activating protein for p21rac. Two transcript variants encoding different isoforms have been found for this gene.
Organism species: Homo sapiens (Human)
- Recombinant protein RPC328Hu01 Recombinant Breakpoint Cluster Region (BCR) In Stock
- Polyclonal antibody PAC328Hu01 Polyclonal Antibody to Breakpoint Cluster Region (BCR) In Stock
- Sandwich ELISA SEC328Hu ELISA Kit for Breakpoint Cluster Region (BCR) In Stock
Organism species: Mus musculus (Mouse)
- Recombinant protein RPC328Mu01 Recombinant Breakpoint Cluster Region (BCR) In Stock
- Polyclonal antibody PAC328Mu01 Polyclonal Antibody to Breakpoint Cluster Region (BCR) In Stock
- Sandwich ELISA SEC328Mu ELISA Kit for Breakpoint Cluster Region (BCR) In Stock
Organism species: Rattus norvegicus (Rat)
- Customized Service n/a Recombinant Breakpoint Cluster Region (BCR) Recombinant Protein Customized Service Offer
- Customized Service n/a Monoclonal Antibody to Breakpoint Cluster Region (BCR) Monoclonal Antibody Customized Service Offer
- Customized Service n/a Polyclonal Antibody to Breakpoint Cluster Region (BCR) Polyclonal Antibody Customized Service Offer
- Customized Service n/a CLIA Kit for Breakpoint Cluster Region (BCR) CLIA Kit Customized Service Offer
- Customized Service n/a ELISA Kit for Breakpoint Cluster Region (BCR) ELISA Kit Customized Service Offer