Ret Proto-Oncogene (RET)
CDHR16; CRet; PTC; CDHF12; HSCR1; MEN2A; MEN2B; MTC1; RET-ELE1; RET51; C-Ret; Multiple Endocrine Neoplasia And Medullary Thyroid Carcinoma 1; Cadherin-Related 16
c-Ret is a member of the cadherin superfamily, encodes one of the receptor tyrosine kinases, which are cell-surface molecules that transduce signals for cell growth and differentiation. This gene plays a crucial role in neural crest development, and it can undergo oncogenic activation in vivo and in vitro by cytogenetic rearrangement.
Mutations in this gene are associated with the disorders multiple endocrine neoplasia, type IIA, multiple endocrine neoplasia, type IIB, Hirschsprung disease, and medullary thyroid carcinoma. Two transcript variants encoding different isoforms have been found for this gene. Additional transcript variants have been described but their biological validity has not been confirmed.
Organism species: Homo sapiens (Human)
- Recombinant protein RPB293Hu01 Recombinant Ret Proto-Oncogene (RET) In Stock
- Customized Service n/a Monoclonal Antibody to Ret Proto-Oncogene (RET) Monoclonal Antibody Customized Service Offer
- Customized Service n/a Polyclonal Antibody to Ret Proto-Oncogene (RET) Polyclonal Antibody Customized Service Offer
- Customized Service n/a CLIA Kit for Ret Proto-Oncogene (RET) CLIA Kit Customized Service Offer
- Customized Service n/a ELISA Kit for Ret Proto-Oncogene (RET) ELISA Kit Customized Service Offer
Organism species: Mus musculus (Mouse)
- Recombinant protein RPB293Mu01 Recombinant Ret Proto-Oncogene (RET) In Stock
- Monoclonal antibody MAB293Mu21 Monoclonal Antibody to Ret Proto-Oncogene (RET) In Stock
- Customized Service n/a CLIA Kit for Ret Proto-Oncogene (RET) CLIA Kit Customized Service Offer
- Customized Service n/a ELISA Kit for Ret Proto-Oncogene (RET) ELISA Kit Customized Service Offer
Organism species: Rattus norvegicus (Rat)
- Customized Service n/a Recombinant Ret Proto-Oncogene (RET) Recombinant Protein Customized Service Offer
- Customized Service n/a Monoclonal Antibody to Ret Proto-Oncogene (RET) Monoclonal Antibody Customized Service Offer
- Customized Service n/a Polyclonal Antibody to Ret Proto-Oncogene (RET) Polyclonal Antibody Customized Service Offer
- Customized Service n/a CLIA Kit for Ret Proto-Oncogene (RET) CLIA Kit Customized Service Offer
- Customized Service n/a ELISA Kit for Ret Proto-Oncogene (RET) ELISA Kit Customized Service Offer