CDGSH Iron Sulfur Domain Protein 2 (CISD2)

ZCD2; WFS2; CDGSH2; Miner1; NAF-1; ERIS; Nutrient-deprivation autophagy factor-1; Wolfram Syndrome 2; Endoplasmic Reticulum Intermembrane Small Protein
CDGSH Iron Sulfur Domain Protein 2 (CISD2)
CISD2 is a zinc finger protein that localizes to the endoplasmic reticulum. The encoded protein binds an iron/sulfur cluster and may be involved in calcium homeostasis. Defects in this gene are a cause of Wolfram syndrome 2 (WFS2).
The mutation disrupted the mRNA splicing by eliminating exon 2, and resulted in the introduction of a premature stop codon. Like wolframin, the CISD2-encoded protein, ERIS (endoplasmic reticulum intermembrane small protein), also localizes to the endoplasmic reticulum.Cisd2 gene is involved in mammalian life span control. In mice, Cisd2 was primarily localized to the mitochondria and associated with the outer mitochondrial membrane. Cisd2-null mice showed early senescence and shortened life span compared to wildtype mice.
Organism species: Homo sapiens (Human)
  • Protein RPL120Hu01Recombinant CDGSH Iron Sulfur Domain Protein 2 (CISD2)Customize
  • AntibodyPAL120Hu01Polyclonal Antibody to CDGSH Iron Sulfur Domain Protein 2 (CISD2)Customize
  • AntibodyMAL120Hu21Monoclonal Antibody to CDGSH Iron Sulfur Domain Protein 2 (CISD2)Customize
  • Assay KitSEL120HuELISA Kit for CDGSH Iron Sulfur Domain Protein 2 (CISD2)Customize
  • Assay KitSCL120HuCLIA Kit for CDGSH Iron Sulfur Domain Protein 2 (CISD2)Customize
Organism species: Mus musculus (Mouse)
  • Protein RPL120Mu01Recombinant CDGSH Iron Sulfur Domain Protein 2 (CISD2)Customize
  • AntibodyPAL120Mu01Polyclonal Antibody to CDGSH Iron Sulfur Domain Protein 2 (CISD2)Customize
  • AntibodyMAL120Mu21Monoclonal Antibody to CDGSH Iron Sulfur Domain Protein 2 (CISD2)Customize
  • Assay KitSEL120MuELISA Kit for CDGSH Iron Sulfur Domain Protein 2 (CISD2)Customize
  • Assay KitSCL120MuCLIA Kit for CDGSH Iron Sulfur Domain Protein 2 (CISD2)Customize
Organism species: Rattus norvegicus (Rat)
  • Protein RPL120Ra01Recombinant CDGSH Iron Sulfur Domain Protein 2 (CISD2)Customize
  • AntibodyPAL120Ra01Polyclonal Antibody to CDGSH Iron Sulfur Domain Protein 2 (CISD2)Customize
  • AntibodyMAL120Ra21Monoclonal Antibody to CDGSH Iron Sulfur Domain Protein 2 (CISD2)Customize
  • Assay KitSEL120RaELISA Kit for CDGSH Iron Sulfur Domain Protein 2 (CISD2)Customize
  • Assay KitSCL120RaCLIA Kit for CDGSH Iron Sulfur Domain Protein 2 (CISD2)Customize
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