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ITEM PROTEIN ANTIBODY ASSAY KIT CELL
CDGSH Iron Sulfur Domain Protein 2 (CISD2)
ZCD2; WFS2; Miner1; ERIS; Zinc Finger,CDGSH-Type Domain 2; Wolfram Syndrome 2; MitoNEET Related 1; Endoplasmic Reticulum Intermembrane Small Protein
CISD2 is a zinc finger protein that localizes to the endoplasmic reticulum. The encoded protein binds an iron/sulfur cluster and may be involved in calcium homeostasis. Defects in this gene are a cause of Wolfram syndrome 2 (WFS2).
The mutation disrupted the mRNA splicing by eliminating exon 2, and resulted in the introduction of a premature stop codon. Like wolframin, the CISD2-encoded protein, ERIS (endoplasmic reticulum intermembrane small protein), also localizes to the endoplasmic reticulum.Cisd2 gene is involved in mammalian life span control. In mice, Cisd2 was primarily localized to the mitochondria and associated with the outer mitochondrial membrane. Cisd2-null mice showed early senescence and shortened life span compared to wildtype mice.
Organism species: Homo sapiens (Human)
CATALOG NO. PRODUCT NAME
Proteins RPL120Hu01 Recombinant CDGSH Iron Sulfur Domain Protein 2 (CISD2) Customize
Antibodies PAL120Hu01 Polyclonal Antibody to CDGSH Iron Sulfur Domain Protein 2 (CISD2) Customize
MAL120Hu21 Monoclonal Antibody to CDGSH Iron Sulfur Domain Protein 2 (CISD2) Customize
Assay Kits SEL120Hu ELISA Kit for CDGSH Iron Sulfur Domain Protein 2 (CISD2) Customize
SCL120Hu CLIA Kit for CDGSH Iron Sulfur Domain Protein 2 (CISD2) Customize
Organism species: Mus musculus (Mouse)
CATALOG NO. PRODUCT NAME
Proteins RPL120Mu01 Recombinant CDGSH Iron Sulfur Domain Protein 2 (CISD2) Customize
Antibodies PAL120Mu01 Polyclonal Antibody to CDGSH Iron Sulfur Domain Protein 2 (CISD2) Customize
MAL120Mu21 Monoclonal Antibody to CDGSH Iron Sulfur Domain Protein 2 (CISD2) Customize
Assay Kits SEL120Mu ELISA Kit for CDGSH Iron Sulfur Domain Protein 2 (CISD2) Customize
SCL120Mu CLIA Kit for CDGSH Iron Sulfur Domain Protein 2 (CISD2) Customize
Organism species: Rattus norvegicus (Rat)
CATALOG NO. PRODUCT NAME
Proteins RPL120Ra01 Recombinant CDGSH Iron Sulfur Domain Protein 2 (CISD2) Customize
Antibodies PAL120Ra01 Polyclonal Antibody to CDGSH Iron Sulfur Domain Protein 2 (CISD2) Customize
MAL120Ra21 Monoclonal Antibody to CDGSH Iron Sulfur Domain Protein 2 (CISD2) Customize
Assay Kits SEL120Ra ELISA Kit for CDGSH Iron Sulfur Domain Protein 2 (CISD2) Customize
SCL120Ra CLIA Kit for CDGSH Iron Sulfur Domain Protein 2 (CISD2) Customize