CDK5 Regulatory Subunit Associated Protein 1 (CDK5RAP1)
C42; CGI-05; HSPC167; C20orf34; CDK5 activator-binding protein C42
Neuronal CDC2-like kinase, which is involved in the regulation of neuronal differentiation, is composed of a catalytic subunit, CDK5, and an activating subunit, p25NCK5A. The protein encoded by this gene binds to p25NCK5A and therefore may be involved in neuronal differentiation. Multiple transcript variants exist for this gene, but the full-length natures of only two have been determined.
Full-length Cdk5rap1 inhibited the kinase activity of the dimer. A C-terminal fragment of mammalian Cdk5rap1 bound with high affinity but was not inhibitory. Ectopic expression of Cdk5rap1 suppressed the differentiation of rat neuroblastoma cells, and expression of the C-terminal fragment had significantly less effect.
Organism species: Homo sapiens (Human)
- Customized Service n/a Recombinant CDK5 Regulatory Subunit Associated Protein 1 (CDK5RAP1) Recombinant Protein Customized Service Offer
- Customized Service n/a Monoclonal Antibody to CDK5 Regulatory Subunit Associated Protein 1 (CDK5RAP1) Monoclonal Antibody Customized Service Offer
- Customized Service n/a Polyclonal Antibody to CDK5 Regulatory Subunit Associated Protein 1 (CDK5RAP1) Polyclonal Antibody Customized Service Offer
- Customized Service n/a CLIA Kit for CDK5 Regulatory Subunit Associated Protein 1 (CDK5RAP1) CLIA Kit Customized Service Offer
- Customized Service n/a ELISA Kit for CDK5 Regulatory Subunit Associated Protein 1 (CDK5RAP1) ELISA Kit Customized Service Offer
Organism species: Mus musculus (Mouse)
- Customized Service n/a Recombinant CDK5 Regulatory Subunit Associated Protein 1 (CDK5RAP1) Recombinant Protein Customized Service Offer
- Customized Service n/a Monoclonal Antibody to CDK5 Regulatory Subunit Associated Protein 1 (CDK5RAP1) Monoclonal Antibody Customized Service Offer
- Customized Service n/a Polyclonal Antibody to CDK5 Regulatory Subunit Associated Protein 1 (CDK5RAP1) Polyclonal Antibody Customized Service Offer
- Customized Service n/a CLIA Kit for CDK5 Regulatory Subunit Associated Protein 1 (CDK5RAP1) CLIA Kit Customized Service Offer
- Customized Service n/a ELISA Kit for CDK5 Regulatory Subunit Associated Protein 1 (CDK5RAP1) ELISA Kit Customized Service Offer
Organism species: Rattus norvegicus (Rat)
- Customized Service n/a Recombinant CDK5 Regulatory Subunit Associated Protein 1 (CDK5RAP1) Recombinant Protein Customized Service Offer
- Customized Service n/a Monoclonal Antibody to CDK5 Regulatory Subunit Associated Protein 1 (CDK5RAP1) Monoclonal Antibody Customized Service Offer
- Customized Service n/a Polyclonal Antibody to CDK5 Regulatory Subunit Associated Protein 1 (CDK5RAP1) Polyclonal Antibody Customized Service Offer
- Customized Service n/a CLIA Kit for CDK5 Regulatory Subunit Associated Protein 1 (CDK5RAP1) CLIA Kit Customized Service Offer
- Customized Service n/a ELISA Kit for CDK5 Regulatory Subunit Associated Protein 1 (CDK5RAP1) ELISA Kit Customized Service Offer