CHRNA7-FAM7A Fusion Protein (CHRFAM7A)

CHRNA7; CHRNA7-DR1; D-10; CHRNA7(cholinergic receptor,nicotinic,alpha 7,exons 5-10)And FAM7A(family with sequence similarity 7A,exons A-E)Fusion

CHRNA7-FAM7A Fusion Protein (CHRFAM7A)
CHRNA7-FAM7A fusion protein is a protein encoded by the CHRFAM7A gene.The family member CHRNA7, which is located on chromosome 15 in a region associated with several neuropsychiatric disorders, is partially duplicated and forms a hybrid with a novel gene from the family with sequence similarity 7 (FAM7A). Alternative splicing has been observed, and two variants exist, for this hybrid gene. The N-terminally truncated products predicted by the largest open reading frames for each variant would lack the majority of the neurotransmitter-gated ion-channel ligand binding domain but retain the transmembrane region that forms the ion channel. Although current evidence supports transcription of this hybrid gene, translation of the nicotinic acetylcholine receptor-like protein-encoding open reading frames has not been confirmed.

Organism species: Homo sapiens (Human)