Calcium Channel, Voltage Dependent, Gamma Subunit 7 (CACNg7)

CACNg7 is structurally similar to the mouse stargazin protein and is a member of the neuronal calcium channel gamma subunit protein family. However, it appears unlikely that the encoded protein is part of a functional calcium channel. Rather, it appears to inhibit the expression of a specific calcium channel subunit.

The deduced 248-amino acid CACNG7 protein contains 4 transmembrane segments and a highly conserved N-glycosylation site in the first extracellular loop. RT-PCR analysis of 24 adult and fetal tissues detected CACNG7 expression in all tissues tested except heart, uterus, placenta, pancreas, and salivary gland.Phylogenetic analysis indicated that CACNG7 is most related to CACNG5.