Calcium Activated Nucleotidase 1 (CANT1)

SCAN1; SHAPY; CAN1; Soluble Ca-Activated Nucleotidase,Isozyme 1; Apyrase homolog; Putative MAPK-activating protein PM09; Putative NF-kappa-B-activating protein 107
Calcium Activated Nucleotidase 1 (CANT1)
It has long been known that the salivary glands of hematophagous (blood-feeding) arthropods secrete soluble apyrases, which are potent nucleotide hydrolyzing enzymes capable of hydrolyzing extracellular ATP and ADP, the latter being a major agonist contributing to platelet aggregation. Only recently, however, has the identification of proteins homologous to these apyrases been reported in non-blood-feeding organisms such as rodents and humans.
SCAN-1 is the homologue of soluble apyrases found in blood-sucking insects. This family of nucleotidases is unrelated in sequence to more well-studied nucleotidases, and very little is known about the enzymatic mechanism. By multiple sequence alignment, eight regions that are highly conserved in the hSCAN-1 family were identified and named.
Organism species: Homo sapiens (Human)
Organism species: Mus musculus (Mouse)
Organism species: Rattus norvegicus (Rat)
  • Protein RPC357Ra01Recombinant Calcium Activated Nucleotidase 1 (CANT1)Customize
  • AntibodyPAC357Ra01Polyclonal Antibody to Calcium Activated Nucleotidase 1 (CANT1)Customize
  • AntibodyMAC357Ra21Monoclonal Antibody to Calcium Activated Nucleotidase 1 (CANT1)Customize
  • Assay KitSEC357RaELISA Kit for Calcium Activated Nucleotidase 1 (CANT1)Customize
  • Assay KitSCC357RaCLIA Kit for Calcium Activated Nucleotidase 1 (CANT1)Customize
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