Calcium Sensing Receptor (CASR)

CAR; FHH; FIH; GPRC2A; HHC; HHC1; NSHPT; PCAR1; Parathyroid cell calcium-sensing receptor 1; Hypocalciuric Hypercalcemia 1; Severe Neonatal Hyperparathyroidism
Calcium Sensing Receptor (CASR)
Extracellular calcium-sensing receptor is a G-protein coupled receptor which senses extracellular levels of calcium ion. In the parathyroid gland, the calcium-sensing receptor controls calcium homeostasis by regulating the release of parathyroid hormone (PTH).
Mutations that inactivate CASR cause familial hypocalciuric hypercalcemia (FHH) (also known as Familial Benign Hypercalcemia because it is generally asymptomatic and does not require treatment), whereas mutations that activate CASR are the cause of autosomal dominant hypocalcemia. An alternatively spliced transcript variant encoding 1088 aa has been found for this gene, but its full-length nature has not been defined.
Organism species: Homo sapiens (Human)
  • Protein RPC414Hu01Recombinant Calcium Sensing Receptor (CASR)Customize
  • AntibodyPAC414Hu01Polyclonal Antibody to Calcium Sensing Receptor (CASR)Customize
  • AntibodyMAC414Hu21Monoclonal Antibody to Calcium Sensing Receptor (CASR)Customize
  • Assay KitSEC414HuELISA Kit for Calcium Sensing Receptor (CASR)In Stock
  • Assay KitSCC414HuCLIA Kit for Calcium Sensing Receptor (CASR)Customize
Organism species: Mus musculus (Mouse)
Organism species: Rattus norvegicus (Rat)
  • Protein RPC414Ra01Recombinant Calcium Sensing Receptor (CASR)Customize
  • AntibodyPAC414Ra01Polyclonal Antibody to Calcium Sensing Receptor (CASR)Customize
  • AntibodyMAC414Ra21Monoclonal Antibody to Calcium Sensing Receptor (CASR)Customize
  • Assay KitSEC414RaELISA Kit for Calcium Sensing Receptor (CASR)In Stock
  • Assay KitSCC414RaCLIA Kit for Calcium Sensing Receptor (CASR)Customize
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