Centrosomal Protein 350kDa (CEP350)

Centrosome-associated protein 350 is a large protein with a CAP-Gly domain typically found in cytoskeleton-associated

proteins. The encoded protein primarily localizes to the centrosome, a non-membraneous organelle that functions as the major microtubule-organizing center in animal cells.

The encoded protein directly interacts with another large centrosomal protein and is required to anchor microtubules at the centrosome. It is also implicated in the regulation of a class of nuclear hormone receptors in the nucleus. Several alternatively spliced transcript variants have been found, but their full-length nature has not been determined.The genomic coordinates used for the transcript record were based on transcript alignments.